CREB1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CREB1
Entrez Gene ID	281713
Full Name	cAMP responsive element binding protein 1
Synonyms	CREB
General protein information	Preferred Names cAMP responsive element binding protein 1 Names cyclic AMP-responsive element-binding protein 1 CREB-1 cyclic AMP-responsive DNA-binding protein
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174285.1	NP_776710.1	cyclic AMP-responsive element-binding protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CREB1	NP_604391.1
Canis lupus familiaris (dog)	CREB1	XP_860219.2
	CREB1	XP_001107192.1
Bos taurus (cattle)	CREB1	NP_776710.1
Rattus norvegicus (Norway rat)	Creb1	NP_112279.1
Pan troglodytes (chimpanzee)	CREB1	XP_516051.2
Mus musculus (house mouse)	Creb1	NP_034082.1
Gallus gallus (chicken)	CREB1	NP_989781.1
Danio rerio (zebrafish)	creb1a	NP_957203.1
Xenopus tropicalis (tropical clawed frog)	creb1	NP_998851.1

Gene Ontology
Bibliography

Related articles in PubMed

Angiotensin II-induced protein kinase D activates the ATF/CREB family of transcription factors and promotes StAR mRNA expression.
Olala LO, Choudhary V, Johnson MH, Bollag WB
Endocrinology155(7)2524-33(2014 Jul)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

CAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular cell adhesion molecule-1 expression in endothelial cells.
Ono H, Ichiki T, Ohtsubo H, Fukuyama K, Imayama I, Iino N, Masuda S, Hashiguchi Y, Takeshita A, Sunagawa K
Hypertension research : official journal of the Japanese Society of Hypertension29(1)39-47(2006 Jan)

Characterization of 954 bovine full-CDS cDNA sequences.
Harhay GP, Sonstegard TS, Keele JW, Heaton MP, Clawson ML, Snelling WM, Wiedmann RT, Van Tassell CP, Smith TP
BMC genomics6166(2005 Nov)

Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells.
Martinson BD, Albert CJ, Corbett JA, Wysolmerski RB, Ford DA
Journal of lipid research44(9)1686-91(2003 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that Ser738/742-to-glutamate protein kinase D mutant increased AngII-induced CREB protein and activating transcription factor 2 phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein promoter.
Title: Angiotensin II-induced protein kinase D activates the ATF/CREB family of transcription factors and promotes StAR mRNA expression.

the p38-MAPK/CREB pathway plays a critical role in TNFalpha-induced VCAM-1 expression
Title: CAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular cell adhesion molecule-1 expression in endothelial cells.

dsRNA as well as other agonists of endothelial cells elicit signaling mechanisms that include in part CREB phosphorylation mediated by calcium-independent phospholipase A2
Title: Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells.

SUMO-1 has a role in modifying cAMP-response element-binding protein CREB in prolonged hypoxia.
Title: Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia.

The following CREB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CREB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43830	NM_174285.1 Latest version!	Bos taurus cAMP responsive element binding protein 1 (CREB1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CREB1 ( NM_174285.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776710.1 Bos taurus cAMP responsive element binding protein 1 (CREB1), mRNA.

Price & Availability↑

CloneID	OBa43830
Clone ID Related Accession (Same CDS sequence)	NM_174285.1
Accession Version	NM_174285.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Bos taurus(cattle)
Product	cyclic AMP-responsive element-binding protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X57031.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X57031.1, AF006042.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END##

ATGGAATCTG GAGCAGAGAA CCAGCAGAGT GGAGATGCAG CTGTAACAGA AGCTGAAAGC 
CAGCAAATGA CAGTTCAAGC CCAGCCACAG ATTGCCACAT TAGCCCAGGT ATCTATGCCA 
GCAGCTCACG CAACATCATC TGCTCCCACC GTAACTTTAG TACAGCTGCC CAATGGGACC 
AAGGTTCAAG TCCATGGAGT TATTCAGGCG GCCCAGCCAT CAGTTATTCA GTCTCCACAA 
GTCCAGACAG TTCAGATTTC AACTATTGCA GAAAGTGAAG ATTCACAGGA GTCAGTGGAT 
AGTGTAACCG ATTCCCAAAA ACGAAGAGAG ATTCTTTCAA GGAGGCCTTC CTACAGGAAA 
ATTTTGAATG ACTTATCTTC TGATGCACCA GGAGTGCCAA GGATTGAAGA AGAGAAATCT 
GAAGAGGAGA CTTCAGCACC TGCCATCACC ACTGTCACGG TGCCAACTCC GATTTATCAG 
ACTAGCAGTG GACAGTATAT TGCCATTACC CAAGGAGGAG CAATACAACT GGCTAACAAT 
GGTACTGATG GGGTACAGGG CCTGCAGACA TTAACCATGA CCAATGCAGC TGCCACTCAG 
CCAGGTACTA CCATCCTGCA GTATGCACAG ACCACTGATG GACAGCAAAT CCTAGTGCCC 
AGCAACCAAG TTGTTGTTCA AGCTGCCTCT GGAGATGTAC AGACATACCA GATTCGCACA 
GCGCCCACTA GCACCATTGC CCCTGGAGTT GTTATGGCGT CTTCCCCAGC ACTTCCTACA 
CAGCCTGCTG AAGAAGCGGC GCGAAAGAGA GAGGTTCGCC TCATGAAGAA CAGGGAAGCA 
GCACGAGAGT GTCGTAGAAA GAAGAAAGAA TATGTGAAAT GTCTAGAAAA CAGAGTGGCA 
GTGCTTGAAA ATCAAAACAA GACACTGATT GAGGAGCTAA AAGCACTTAA GGACCTTTAC 
TGCCACAAAT CAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776710.1
CDS	12..989
Translation	MESGAENQQSGDAAVTEAESQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGTKVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD

Target ORF information:

RefSeq Version	NM_174285.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cAMP responsive element binding protein 1 (CREB1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174285.1

ORF Insert Sequence:

ATGGAATCTG GAGCAGAGAA CCAGCAGAGT GGAGATGCAG CTGTAACAGA AGCTGAAAGC 
CAGCAAATGA CAGTTCAAGC CCAGCCACAG ATTGCCACAT TAGCCCAGGT ATCTATGCCA 
GCAGCTCACG CAACATCATC TGCTCCCACC GTAACTTTAG TACAGCTGCC CAATGGGACC 
AAGGTTCAAG TCCATGGAGT TATTCAGGCG GCCCAGCCAT CAGTTATTCA GTCTCCACAA 
GTCCAGACAG TTCAGATTTC AACTATTGCA GAAAGTGAAG ATTCACAGGA GTCAGTGGAT 
AGTGTAACCG ATTCCCAAAA ACGAAGAGAG ATTCTTTCAA GGAGGCCTTC CTACAGGAAA 
ATTTTGAATG ACTTATCTTC TGATGCACCA GGAGTGCCAA GGATTGAAGA AGAGAAATCT 
GAAGAGGAGA CTTCAGCACC TGCCATCACC ACTGTCACGG TGCCAACTCC GATTTATCAG 
ACTAGCAGTG GACAGTATAT TGCCATTACC CAAGGAGGAG CAATACAACT GGCTAACAAT 
GGTACTGATG GGGTACAGGG CCTGCAGACA TTAACCATGA CCAATGCAGC TGCCACTCAG 
CCAGGTACTA CCATCCTGCA GTATGCACAG ACCACTGATG GACAGCAAAT CCTAGTGCCC 
AGCAACCAAG TTGTTGTTCA AGCTGCCTCT GGAGATGTAC AGACATACCA GATTCGCACA 
GCGCCCACTA GCACCATTGC CCCTGGAGTT GTTATGGCGT CTTCCCCAGC ACTTCCTACA 
CAGCCTGCTG AAGAAGCGGC GCGAAAGAGA GAGGTTCGCC TCATGAAGAA CAGGGAAGCA 
GCACGAGAGT GTCGTAGAAA GAAGAAAGAA TATGTGAAAT GTCTAGAAAA CAGAGTGGCA 
GTGCTTGAAA ATCAAAACAA GACACTGATT GAGGAGCTAA AAGCACTTAA GGACCTTTAC 
TGCCACAAAT CAGATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Angiotensin II-induced protein kinase D activates the ATF/CREB family of transcription factors and promotes StAR mRNA expression.
Endocrinology155(7)2524-33(2014 Jul)
Olala LO,Choudhary V,Johnson MH,Bollag WB

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

CAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular cell adhesion molecule-1 expression in endothelial cells.
Hypertension research : official journal of the Japanese Society of Hypertension29(1)39-47(2006 Jan)
Ono H,Ichiki T,Ohtsubo H,Fukuyama K,Imayama I,Iino N,Masuda S,Hashiguchi Y,Takeshita A,Sunagawa K

Characterization of 954 bovine full-CDS cDNA sequences.
BMC genomics6166(2005 Nov)
Harhay GP,Sonstegard TS,Keele JW,Heaton MP,Clawson ML,Snelling WM,Wiedmann RT,Van Tassell CP,Smith TP

Calcium-independent phospholipase A2 mediates CREB phosphorylation in double-stranded RNA-stimulated endothelial cells.
Journal of lipid research44(9)1686-91(2003 Sep)
Martinson BD,Albert CJ,Corbett JA,Wysolmerski RB,Ford DA

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CREB1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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