STAR cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	STAR
Entrez Gene ID	281507
Full Name	steroidogenic acute regulatory protein
General protein information	Preferred Names steroidogenic acute regulatory protein Names steroidogenic acute regulatory protein, mitochondrial START domain-containing protein 1 stARD1 steroidogenic acute regulator
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174189.2	NP_776614.1	steroidogenic acute regulatory protein, mitochondrial precursor
NM_174189.3	NP_776614.2	steroidogenic acute regulatory protein, mitochondrial precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	STAR	XP_001170375.1
Canis lupus familiaris (dog)	STAR	NP_001091011.1
Rattus norvegicus (Norway rat)	Star	NP_113746.1
Homo sapiens (human)	STAR	NP_000340.2
	STAR	XP_001090472.1
Danio rerio (zebrafish)	star	NP_571738.1
Xenopus tropicalis (tropical clawed frog)	LOC100492318	XP_002932770.1
Bos taurus (cattle)	STAR	NP_776614.1
Mus musculus (house mouse)	Star	NP_035615.2
Gallus gallus (chicken)	STAR	NP_990017.1

Gene Ontology
Bibliography

Related articles in PubMed

Angiotensin II-induced protein kinase D activates the ATF/CREB family of transcription factors and promotes StAR mRNA expression.
Olala LO, Choudhary V, Johnson MH, Bollag WB
Endocrinology155(7)2524-33(2014 Jul)

Escherichia coli lipopolysaccharide administration transiently suppresses luteal structure and function in diestrous cows.
Herzog K, Str?ve K, Kastelic JP, Piechotta M, Ulbrich SE, Pfarrer C, Shirasuna K, Shimizu T, Miyamoto A, Bollwein H
Reproduction (Cambridge, England)144(4)467-76(2012 Oct)

Luteinizing hormone (LH) regulates production of androstenedione and progesterone via control of histone acetylation of StAR and CYP17 promoters in ovarian theca cells.
Murayama C, Miyazaki H, Miyamoto A, Shimizu T
Molecular and cellular endocrinology350(1)1-9(2012 Mar)

BMP-4 suppresses progesterone production by inhibiting histone H3 acetylation of StAR in bovine granulosa cells in vitro.
Yamashita H, Murayama C, Takasugi R, Miyamoto A, Shimizu T
Molecular and cellular biochemistry348(1-2)183-90(2011 Feb)

c-Fos mediates angiotensin II-induced aldosterone production and protein synthesis in bovine adrenal glomerulosa cells.
Rincon Garriz JM, Suarez C, Capponi AM
Endocrinology150(3)1294-302(2009 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that Ser738/742-to-glutamate protein kinase D mutant increased AngII-induced CREB protein and activating transcription factor 2 phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein promoter.
Title: Angiotensin II-induced protein kinase D activates the ATF/CREB family of transcription factors and promotes StAR mRNA expression.

Data suggest that Escherichia coli infections (here, administration of LPS) provokes luteolysis in diestrus, non-lactating cows and down-regulation of expression of StAR in corpus luteum but has no effect on luteinization in the following cycle.
Title: Escherichia coli lipopolysaccharide administration transiently suppresses luteal structure and function in diestrous cows.

The binding of SF-1 to the CYP17 and StAR promoter regions increased in theca cells incubated with low levels of luteinizing hormone.
Title: Luteinizing hormone (LH) regulates production of androstenedione and progesterone via control of histone acetylation of StAR and CYP17 promoters in ovarian theca cells.

Inhibition of the acetylation of histone H3 associated with the StAR promoter region by BMP-4 may be one of the inhibitory molecular mechanisms of progesterone synthesis in granulosa cells.
Title: BMP-4 suppresses progesterone production by inhibiting histone H3 acetylation of StAR in bovine granulosa cells in vitro.

c-Fos/c-Jun complex binds to the proximal StAR promoter in glomerulosa cells, thus activating StAR gene expression and acute aldosterone biosynthesis.
Title: c-Fos mediates angiotensin II-induced aldosterone production and protein synthesis in bovine adrenal glomerulosa cells.

The following STAR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa238846	NM_174189.3 Latest version!	Bos taurus steroidogenic acute regulatory protein (STAR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OBa41515	NM_174189.2 Latest version!	Bos taurus steroidogenic acute regulatory protein (STAR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STAR ( NM_174189.3 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776614.2 Bos taurus steroidogenic acute regulatory protein (STAR), mRNA.

Price & Availability↑

CloneID	OBa238846
Clone ID Related Accession (Same CDS sequence)	NM_174189.3
Accession Version	NM_174189.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-13
Organism	Bos taurus(cattle)
Product	steroidogenic acute regulatory protein, mitochondrial precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DAAA02060845.1. On Jan 18, 2018 this sequence version replaced NM_174189.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: Y17259.1, EH175874.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145433, SAMN03145439 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGCTTCTCG CGACGTTTAA GCTGTGTGCC GGAAGCTCCT ACAGACATGT GCGCAGCATG 
AAGGGGCTGC AGCAGCAGGC TGTGCTGGCC ATCGGCCAGG AGCTGAACCG GAGGGCCCTA 
GGGGGCCCGG CCCCAGCTGC GTGGATTAAC CAGGTTCGGC GTCGCGGCTC TCTCCTAGGT 
TCTCAGCTGG AAGACCCTCT CTACAGCGAC CAAGAGCTGG CCTATATCCA GCAGGGAGAG 
GAGGCCATGC AGAGGGCCCT GGGCATCCTC AAAGACCAGG AGGGCTGGAA GAAGGAGAGC 
CGGCAGGCCA ATGGGGACGA GGTGCTGAGT AAAGTGATCC CTGACGTGGG CAAGGTGTTC 
CGGTTGGAGG TGGTGGTGGA CCAGCCCATG GAGAGGCTTT ATGAAGAGCT TGTGGAGCGC 
ATGGAGGCCA TGGGCGAGTG GAATCCCAAC GTCAAGGAGA TCAAGGTCCT GCAGAAGATT 
GGAAAAGACA CGGTCATCAC TCACGAGTTG GCTGCAGAGG TGGCAGGAAA CCTTGTGGGG 
CCCCGAGACT TTGTGAGCGT ACGCTGTACC AAGCGCCGGG GCTCCATGTG TGTGCTGGCT 
GGCATGGCCA CACTCTATGA GGAGATGCCC CAGCAGAAGG GTGTCATCAG AGCGGAGCAC 
GGCCCCACCT GCATGGTGCT CCGCCCCTTG GCTGGAAGTC CCTCAAGGAC CAAACTCACC 
TGGCTGCTCA GCATTGACCT CAAGGGATGG CTGCCGAAGA CCATCATCAA CCAGGTCCTC 
TCGCAGACCC AGGTGGATTT TGCCAATCAC CTGCGCAAGC GCCTGGAGTC CTGCCCTGCT 
CTTGAAGCTA GGTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776614.2
CDS	137..994
Translation	MLLATFKLCAGSSYRHVRSMKGLQQQAVLAIGQELNRRALGGPAPAAWINQVRRRGSLLGSQLEDPLYSDQELAYIQQGEEAMQRALGILKDQEGWKKESRQANGDEVLSKVIPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTVITHELAAEVAGNLVGPRDFVSVRCTKRRGSMCVLAGMATLYEEMPQQKGVIRAEHGPTCMVLRPLAGSPSRTKLTWLLSIDLKGWLPKTIINQVLSQTQVDFANHLRKRLESCPALEARC

Target ORF information:

RefSeq Version	NM_174189.3
Organism	Bos taurus(cattle)
Definition	Bos taurus steroidogenic acute regulatory protein (STAR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174189.3

ORF Insert Sequence:

ATGCTTCTCG CGACGTTTAA GCTGTGTGCC GGAAGCTCCT ACAGACATGT GCGCAGCATG 
AAGGGGCTGC AGCAGCAGGC TGTGCTGGCC ATCGGCCAGG AGCTGAACCG GAGGGCCCTA 
GGGGGCCCGG CCCCAGCTGC GTGGATTAAC CAGGTTCGGC GTCGCGGCTC TCTCCTAGGT 
TCTCAGCTGG AAGACCCTCT CTACAGCGAC CAAGAGCTGG CCTATATCCA GCAGGGAGAG 
GAGGCCATGC AGAGGGCCCT GGGCATCCTC AAAGACCAGG AGGGCTGGAA GAAGGAGAGC 
CGGCAGGCCA ATGGGGACGA GGTGCTGAGT AAAGTGATCC CTGACGTGGG CAAGGTGTTC 
CGGTTGGAGG TGGTGGTGGA CCAGCCCATG GAGAGGCTTT ATGAAGAGCT TGTGGAGCGC 
ATGGAGGCCA TGGGCGAGTG GAATCCCAAC GTCAAGGAGA TCAAGGTCCT GCAGAAGATT 
GGAAAAGACA CGGTCATCAC TCACGAGTTG GCTGCAGAGG TGGCAGGAAA CCTTGTGGGG 
CCCCGAGACT TTGTGAGCGT ACGCTGTACC AAGCGCCGGG GCTCCATGTG TGTGCTGGCT 
GGCATGGCCA CACTCTATGA GGAGATGCCC CAGCAGAAGG GTGTCATCAG AGCGGAGCAC 
GGCCCCACCT GCATGGTGCT CCGCCCCTTG GCTGGAAGTC CCTCAAGGAC CAAACTCACC 
TGGCTGCTCA GCATTGACCT CAAGGGATGG CTGCCGAAGA CCATCATCAA CCAGGTCCTC 
TCGCAGACCC AGGTGGATTT TGCCAATCAC CTGCGCAAGC GCCTGGAGTC CTGCCCTGCT 
CTTGAAGCTA GGTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STAR ( NM_174189.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776614.1 Bos taurus steroidogenic acute regulatory protein (STAR), mRNA.

Price & Availability↑

CloneID	OBa41515
Clone ID Related Accession (Same CDS sequence)	NM_174189.2
Accession Version	NM_174189.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-21
Organism	Bos taurus(cattle)
Product	steroidogenic acute regulatory protein, mitochondrial precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y17259.1. On Jun 3, 2003 this sequence version replaced NM_174189.1. ##Evidence-Data-START## Transcript exon combination :: Y17259.1, EH175874.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02403646, SAMN04019679 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGCTGCTCG CGACGTTTAA GCTGTGTGCC GGAAGCTCCT ACAGACATGT GCGCAGCATG 
AAGGGGCTGC AGCAGCAGGC TGTGCTGGCC ATCGGCCAGG AGCTGAACCG GAGGGCCCTA 
GGGGGCCCGG CCCCAGCTGC GTGGATTAAC CAGGTTCGGC GTCGCGGCTC TCTCCTAGGT 
TCTCAGCTGG AAGACCCTCT CTACAGCGAC CAAGAGCTGG CCCATATCCA GCAGGGAGAG 
GAGGCCATGC AGTGGGCCCT GGGCATCCTC AAAGACCAGG AGGGCTGGAA GAAGGAGAGC 
CGGCAGGCCA ATGGGGACGA GGTGCTGAGT AAAGTGATCC CTGACGTGGG CAAGGTGTTC 
CGGTTGGAGG TGGTGGTGGA CCAGCCCATG GAGAGGCTTT ATGAAGAGCT TGTGGAGCGC 
ATGGAGGCCA TGGGCGAGTG GAATCCCAAT GTCAAGGAGA TCAAGGTCCT GCAGAAGATT 
GGAAAAGACA CGGTCATCAC TCACGAGTTG GCTGCAGAGG CGGCAGGAAA CCTCGTGGGG 
CCCCGAGACT TTGTGAGCGT ACGCTGTACC AAGCGCCGGG GCTCCATGTG TGTGCTGGCT 
GGCATGGCCA CACTCTATGA GGAGATGCCC CAGCAGAAGG GTGTCATCAG AGCGGAGCAC 
GGCCCCACCT GCATGGTGCT CCGCCCCTTG GCTGGAAGTC CCTCAAGGAC CAAACTCACC 
TGGCTGCTCA GCATTGACCT CAAGGGATGG CTGCCGAAGA CCATCATCAA CCAGGTCCTC 
TCGCAGACCC AGGTGGATTT TGCCAATCAC CTGCGCAAGC GCCTGGAGTC CTGCCCTGCT 
CTTGAAGCTA GGTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776614.1
CDS	137..994
Translation	MLLATFKLCAGSSYRHVRSMKGLQQQAVLAIGQELNRRALGGPAPAAWINQVRRRGSLLGSQLEDPLYSDQELAHIQQGEEAMQWALGILKDQEGWKKESRQANGDEVLSKVIPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTVITHELAAEAAGNLVGPRDFVSVRCTKRRGSMCVLAGMATLYEEMPQQKGVIRAEHGPTCMVLRPLAGSPSRTKLTWLLSIDLKGWLPKTIINQVLSQTQVDFANHLRKRLESCPALEARC

Target ORF information:

RefSeq Version	NM_174189.2
Organism	Bos taurus(cattle)
Definition	Bos taurus steroidogenic acute regulatory protein (STAR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174189.2

ORF Insert Sequence:

ATGCTGCTCG CGACGTTTAA GCTGTGTGCC GGAAGCTCCT ACAGACATGT GCGCAGCATG 
AAGGGGCTGC AGCAGCAGGC TGTGCTGGCC ATCGGCCAGG AGCTGAACCG GAGGGCCCTA 
GGGGGCCCGG CCCCAGCTGC GTGGATTAAC CAGGTTCGGC GTCGCGGCTC TCTCCTAGGT 
TCTCAGCTGG AAGACCCTCT CTACAGCGAC CAAGAGCTGG CCCATATCCA GCAGGGAGAG 
GAGGCCATGC AGTGGGCCCT GGGCATCCTC AAAGACCAGG AGGGCTGGAA GAAGGAGAGC 
CGGCAGGCCA ATGGGGACGA GGTGCTGAGT AAAGTGATCC CTGACGTGGG CAAGGTGTTC 
CGGTTGGAGG TGGTGGTGGA CCAGCCCATG GAGAGGCTTT ATGAAGAGCT TGTGGAGCGC 
ATGGAGGCCA TGGGCGAGTG GAATCCCAAT GTCAAGGAGA TCAAGGTCCT GCAGAAGATT 
GGAAAAGACA CGGTCATCAC TCACGAGTTG GCTGCAGAGG CGGCAGGAAA CCTCGTGGGG 
CCCCGAGACT TTGTGAGCGT ACGCTGTACC AAGCGCCGGG GCTCCATGTG TGTGCTGGCT 
GGCATGGCCA CACTCTATGA GGAGATGCCC CAGCAGAAGG GTGTCATCAG AGCGGAGCAC 
GGCCCCACCT GCATGGTGCT CCGCCCCTTG GCTGGAAGTC CCTCAAGGAC CAAACTCACC 
TGGCTGCTCA GCATTGACCT CAAGGGATGG CTGCCGAAGA CCATCATCAA CCAGGTCCTC 
TCGCAGACCC AGGTGGATTT TGCCAATCAC CTGCGCAAGC GCCTGGAGTC CTGCCCTGCT 
CTTGAAGCTA GGTGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Angiotensin II-induced protein kinase D activates the ATF/CREB family of transcription factors and promotes StAR mRNA expression.
Endocrinology155(7)2524-33(2014 Jul)
Olala LO,Choudhary V,Johnson MH,Bollag WB

Escherichia coli lipopolysaccharide administration transiently suppresses luteal structure and function in diestrous cows.
Reproduction (Cambridge, England)144(4)467-76(2012 Oct)
Herzog K,Str?ve K,Kastelic JP,Piechotta M,Ulbrich SE,Pfarrer C,Shirasuna K,Shimizu T,Miyamoto A,Bollwein H

Luteinizing hormone (LH) regulates production of androstenedione and progesterone via control of histone acetylation of StAR and CYP17 promoters in ovarian theca cells.
Molecular and cellular endocrinology350(1)1-9(2012 Mar)
Murayama C,Miyazaki H,Miyamoto A,Shimizu T

BMP-4 suppresses progesterone production by inhibiting histone H3 acetylation of StAR in bovine granulosa cells in vitro.
Molecular and cellular biochemistry348(1-2)183-90(2011 Feb)
Yamashita H,Murayama C,Takasugi R,Miyamoto A,Shimizu T

c-Fos mediates angiotensin II-induced aldosterone production and protein synthesis in bovine adrenal glomerulosa cells.
Endocrinology150(3)1294-302(2009 Mar)
Rincon Garriz JM,Suarez C,Capponi AM

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STAR cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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