INHA cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	INHA
Entrez Gene ID	281254
Full Name	inhibin alpha subunit
General protein information	Preferred Names inhibin alpha subunit Names inhibin alpha chain inhibin A inhibin, alpha
Gene Type	protein-coding
Organism	Bos taurus(cattle)
Genome	Chromosome: 2 Map Location: 2q36-q42

mRNA and Protein(s)

mRNA	Protein	Name
NM_174094.4	NP_776519.2	inhibin alpha chain precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Inha	NP_036722.1
Mus musculus (house mouse)	Inha	NP_034694.3
Gallus gallus (chicken)	INHA	NP_001026428.1
Xenopus tropicalis (tropical clawed frog)	inha	NP_001027522.1
Homo sapiens (human)	INHA	NP_002182.1
Canis lupus familiaris (dog)	INHA	XP_545660.1
Danio rerio (zebrafish)	inha	NP_001038669.1
Pan troglodytes (chimpanzee)	INHA	XP_001148064.1
	INHA	NP_001028127.1
Bos taurus (cattle)	INHA	NP_776519.2

Gene Ontology
Bibliography

Related articles in PubMed

Anti-Muellerian hormone, inhibin A, gonadotropins, and gonadotropin receptors in bull calves after partial scrotal resection, orchidectomy, and Burdizzo castration.
Scarlet D, Aurich C, Ille N, Walter I, Weber C, Pieler D, Peinhopf W, Wohlsein P, Aurich J
Theriogenology87242-249(2017 Jan)

Role of activin, inhibin, and follistatin in the pathogenesis of bovine cystic ovarian disease.
Stangaferro ML, Matiller V, D?az PU, Ortega HH, Rey F, Rodr?guez FM, Silva MA, Salvetti NR
Animal reproduction science148(3-4)97-108(2014 Aug)

An MspI polymorphism in the inhibin alpha gene and its associations with superovulation traits in Chinese Holstein cows.
Tang KQ, Li SJ, Yang WC, Yu JN, Han L, Li X, Yang LG
Molecular biology reports38(1)17-21(2011 Jan)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Effect of overexpression of inhibin alpha (1-32) fragment on bovine granulosa cell proliferation, apoptosis, steroidogenesis, and development of co-cultured oocytes.
Geng LY, Fang M, Yi JM, Jiang F, Moeen-ud-Din M, Yang LG
Theriogenology70(1)35-43(2008 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The effects of castration and other surgical intervention on the blood levels of anti-Muellerian hormone, inhibin A, gonadotropins, and gonadotropin receptors in bull calves are reported.
Title: Anti-Muellerian hormone, inhibin A, gonadotropins, and gonadotropin receptors in bull calves after partial scrotal resection, orchidectomy, and Burdizzo castration.

The expression of the components of the activin-inhibin-follistatin system is altered in bovine cystic ovarian disease.
Title: Role of activin, inhibin, and follistatin in the pathogenesis of bovine cystic ovarian disease.

INHA gene can be used as a predictor for superovulation in Chinese Holstein cows.
Title: An MspI polymorphism in the inhibin alpha gene and its associations with superovulation traits in Chinese Holstein cows.

overexpression of inhibin alpha (1-32) fragment regulated granulosa cell development and effects on subsequent oocyte maturation were both time- and stage-dependent
Title: Effect of overexpression of inhibin alpha (1-32) fragment on bovine granulosa cell proliferation, apoptosis, steroidogenesis, and development of co-cultured oocytes.

Inhibin has a negative autocrine or paracrine effect on the in vitro capacity of granulosa cells isolated from dominant or subordinate follicles to produce estradiol.
Title: Evidence for a negative intrafollicular role for inhibin in regulation of estradiol production by granulosa cells.

The following INHA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INHA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa00743	NM_174094.4 Latest version!	Bos taurus inhibin subunit alpha (INHA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

INHA ( NM_174094.4 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776519.2 Bos taurus inhibin subunit alpha (INHA), mRNA.

Price & Availability↑

CloneID	OBa00743
Clone ID Related Accession (Same CDS sequence)	NM_174094.4
Accession Version	NM_174094.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Bos taurus(cattle)
Product	inhibin alpha chain precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC109837.1. On Aug 31, 2012 this sequence version replaced NM_174094.3. ##Evidence-Data-START## Transcript exon combination :: BC109837.1, M13273.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END##

ATGTGGCTTC AGCTGCTCCT CTTGCTGCTG GCCCCTCAGG GCGGGCATGG CTGTCATGGG 
CTGGAGCTGG ACCGGGAACT TGTCCTGGCC AAGGTGAGGG CCCTGTTTCT GGATGCCTTG 
GGGCACCCAC CGGTGACTGG GGAAGGTGGA GATCCTGGAG TCAGGCGTCT GCACCGAAGG 
CATGCCGTGG GGGGCTTCAT GCGCAGGGGC TCTGAGCCCG AGGACCAAGA TGTCTCCCAG 
GCCATCCTTT TTCCGGCTGC AGGTGCCAGC TGCGGGGATG AGCCAGATGC TGGAGAGGCT 
GAGGAGGGCC TCTTCACGTA TGTGTTCCAG CCATCCCAGC ACACACGCAG CCGCCAGGTG 
ACTTCGGCCC AGCTGTGGTT CCACACAGGA CTGGACAGAC AGGAGACCGC TGCCGCCAAC 
AGCTCTGAGC CCCTGCTTGG CCTGCTGGTA CTGACATCCG GGGGTCCCAT GCCTGTGCCC 
ATGTCGCTGG GCCAGGCCCC CCCTCGCTGG GCTGTCCTGC ACCTGGCCAC CTCCGCCTTC 
CCTCTGCTGA CCCATCCTGT CCTGGCGCTC CTGCTGCGTT GTCCTCTCTG TTCCTGCTCC 
ACTCGGCCCG AAGCCACCCC CTTCCTGGTG GCCCACACAC GGGCCAAGCC GCCCAGTGGA 
GGGGAGAGGG CCCGGCGCTC CACGCCCCCA CTGCCCTGGC CTTGGTCTCC CGCTGCGCTG 
CGCCTGCTGC AGAGGCCTCC AGAGGAGCCC GCCGCCCATG CCGACTGCCA CAGAGCCGCC 
CTCAATATCT CCTTCCAGGA GCTGGGCTGG GACCGGTGGA TAGTGCACCC TCCCAGTTTC 
ATCTTCTACT ACTGTCATGG GGGGTGTGGG CTGTCCCCCC CACAGGACCT GCCCCTGCCG 
GTCCCCGGGG TGCCTCCTAC CCCTGTCCAG CCCCTCTCTC TGGTCCCAGG GGCCCAGCCC 
TGTTGCGCTG CCCTCCCGGG AACCATGAGG CCCCTACACG TCCGCACCAC CTCGGATGGA 
GGTTACTCTT TTAAGTATGA GATGGTGCCC AACCTTCTCA CCCAGCACTG TGCTTGCATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776519.2
CDS	16..1098
Translation	MWLQLLLLLLAPQGGHGCHGLELDRELVLAKVRALFLDALGHPPVTGEGGDPGVRRLHRRHAVGGFMRRGSEPEDQDVSQAILFPAAGASCGDEPDAGEAEEGLFTYVFQPSQHTRSRQVTSAQLWFHTGLDRQETAAANSSEPLLGLLVLTSGGPMPVPMSLGQAPPRWAVLHLATSAFPLLTHPVLALLLRCPLCSCSTRPEATPFLVAHTRAKPPSGGERARRSTPPLPWPWSPAALRLLQRPPEEPAAHADCHRAALNISFQELGWDRWIVHPPSFIFYYCHGGCGLSPPQDLPLPVPGVPPTPVQPLSLVPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYEMVPNLLTQHCACI

Target ORF information:

RefSeq Version	NM_174094.4
Organism	Bos taurus(cattle)
Definition	Bos taurus inhibin subunit alpha (INHA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174094.4

ORF Insert Sequence:

ATGTGGCTTC AGCTGCTCCT CTTGCTGCTG GCCCCTCAGG GCGGGCATGG CTGTCATGGG 
CTGGAGCTGG ACCGGGAACT TGTCCTGGCC AAGGTGAGGG CCCTGTTTCT GGATGCCTTG 
GGGCACCCAC CGGTGACTGG GGAAGGTGGA GATCCTGGAG TCAGGCGTCT GCACCGAAGG 
CATGCCGTGG GGGGCTTCAT GCGCAGGGGC TCTGAGCCCG AGGACCAAGA TGTCTCCCAG 
GCCATCCTTT TTCCGGCTGC AGGTGCCAGC TGCGGGGATG AGCCAGATGC TGGAGAGGCT 
GAGGAGGGCC TCTTCACGTA TGTGTTCCAG CCATCCCAGC ACACACGCAG CCGCCAGGTG 
ACTTCGGCCC AGCTGTGGTT CCACACAGGA CTGGACAGAC AGGAGACCGC TGCCGCCAAC 
AGCTCTGAGC CCCTGCTTGG CCTGCTGGTA CTGACATCCG GGGGTCCCAT GCCTGTGCCC 
ATGTCGCTGG GCCAGGCCCC CCCTCGCTGG GCTGTCCTGC ACCTGGCCAC CTCCGCCTTC 
CCTCTGCTGA CCCATCCTGT CCTGGCGCTC CTGCTGCGTT GTCCTCTCTG TTCCTGCTCC 
ACTCGGCCCG AAGCCACCCC CTTCCTGGTG GCCCACACAC GGGCCAAGCC GCCCAGTGGA 
GGGGAGAGGG CCCGGCGCTC CACGCCCCCA CTGCCCTGGC CTTGGTCTCC CGCTGCGCTG 
CGCCTGCTGC AGAGGCCTCC AGAGGAGCCC GCCGCCCATG CCGACTGCCA CAGAGCCGCC 
CTCAATATCT CCTTCCAGGA GCTGGGCTGG GACCGGTGGA TAGTGCACCC TCCCAGTTTC 
ATCTTCTACT ACTGTCATGG GGGGTGTGGG CTGTCCCCCC CACAGGACCT GCCCCTGCCG 
GTCCCCGGGG TGCCTCCTAC CCCTGTCCAG CCCCTCTCTC TGGTCCCAGG GGCCCAGCCC 
TGTTGCGCTG CCCTCCCGGG AACCATGAGG CCCCTACACG TCCGCACCAC CTCGGATGGA 
GGTTACTCTT TTAAGTATGA GATGGTGCCC AACCTTCTCA CCCAGCACTG TGCTTGCATC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Anti-Muellerian hormone, inhibin A, gonadotropins, and gonadotropin receptors in bull calves after partial scrotal resection, orchidectomy, and Burdizzo castration.
Theriogenology87242-249(2017 Jan)
Scarlet D,Aurich C,Ille N,Walter I,Weber C,Pieler D,Peinhopf W,Wohlsein P,Aurich J

Role of activin, inhibin, and follistatin in the pathogenesis of bovine cystic ovarian disease.
Animal reproduction science148(3-4)97-108(2014 Aug)
Stangaferro ML,Matiller V,D?az PU,Ortega HH,Rey F,Rodr?guez FM,Silva MA,Salvetti NR

An MspI polymorphism in the inhibin alpha gene and its associations with superovulation traits in Chinese Holstein cows.
Molecular biology reports38(1)17-21(2011 Jan)
Tang KQ,Li SJ,Yang WC,Yu JN,Han L,Li X,Yang LG

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Effect of overexpression of inhibin alpha (1-32) fragment on bovine granulosa cell proliferation, apoptosis, steroidogenesis, and development of co-cultured oocytes.
Theriogenology70(1)35-43(2008 Jul)
Geng LY,Fang M,Yi JM,Jiang F,Moeen-ud-Din M,Yang LG

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INHA cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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