Gene Symbol | FSHB |
Entrez Gene ID | 281171 |
Full Name | follicle stimulating hormone beta subunit |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
ORF » Species Summary » Bos taurus » FSHB cDNA ORF clone
Gene Symbol | FSHB |
Entrez Gene ID | 281171 |
Full Name | follicle stimulating hormone beta subunit |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_174060.1 | NP_776485.1 | follitropin subunit beta precursor |
Pan troglodytes (chimpanzee) | FSHB | NP_001065282.1 |
FSHB | XP_001087914.1 | |
Danio rerio (zebrafish) | fshb | NP_991187.1 |
Xenopus tropicalis (tropical clawed frog) | fshb | XP_002937726.1 |
Canis lupus familiaris (dog) | FSHB | XP_542546.2 |
Gallus gallus (chicken) | FSHB | NP_989588.1 |
Bos taurus (cattle) | FSHB | NP_776485.1 |
Rattus norvegicus (Norway rat) | Fshb | NP_001007598.1 |
Homo sapiens (human) | FSHB | NP_001018090.1 |
Mus musculus (house mouse) | Fshb | NP_032071.1 |
Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage.
Wang H, Hastings R, Miller WL, Kumar TR
Molecular and cellular endocrinology419124-38(2016 Jan)
Naturally occurring genetic mutations in the 5'-upstream regulatory region of bovine FSHB generate a novel cis-regulatory element that affects its expression.
Dai L, Xu Y, Yu W, Liu S, Gao Y, Zhang L, Yuan B, Chen J, Ma T, Zhang J
Animal genetics46(6)693-6(2015 Dec)
Molecular cloning and sequence analysis of follicle-stimulating hormone beta polypeptide precursor cDNA from the bovine pituitary gland.
Dai LS, Zhao YM, Zhang GL, Zhao RF, Jiang H, Ma TH, Gao Y, Yuan B, Xu YL, Yu WY, Zhao ZH, Zhang JB
Genetics and molecular research : GMR10(3)1504-13(2011)
Effects of novel single nucleotide polymorphisms of the FSH beta-subunit gene on semen quality and fertility in bulls.
Dai L, Zhao Z, Zhao R, Xiao S, Jiang H, Yue X, Li X, Gao Y, Liu J, Zhang J
Animal reproduction science114(1-3)14-22(2009 Aug)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study describes generation and characterization of a new Fshb-iCre deleter strain using 4.7 kb of ovine Fshb promoter sequences driving iCre expression exclusively in the gonadotrope lineage with mice developing normally, and fertile.
Title: Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage.
the novel cis-regulatory element generated by the c.-1539_-1538delGGinsTTAACT mutations might play an important role in repressing FSHB transcription, possibly leading to reduced fertility
Title: Naturally occurring genetic mutations in the 5'-upstream regulatory region of bovine FSHB generate a novel cis-regulatory element that affects its expression.
The effect of a single nucleotide polymorphism of the follicle stimulating hormone beta chain on bull fertility and semen quality is reported.
Title: Effects of novel single nucleotide polymorphisms of the FSH beta-subunit gene on semen quality and fertility in bulls.
The shift in FSH isoforms toward a greater abundance of the less acidic isoforms appears to be a key component in determining the capability for producing a preovulatory rise in estradiol.
Title: Follicle-stimulating hormone isoforms and plasma concentrations of estradiol and inhibin A in dairy cows with ovulatory and non-ovulatory follicles during the first postpartum follicle wave.
A 200-base region in the bovine FSHbeta 3' untranslated region downregulates reporter expression at the translational level via interactions between AREs in both the 3'UTR and transfactors.
Title: The 3' untranslated region of bovine follicle-stimulating hormone beta messenger RNA downregulates reporter expression: involvement of AU-rich elements and transfactors.
The following FSHB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FSHB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41560 | |
Clone ID Related Accession (Same CDS sequence) | NM_174060.1 | |
Accession Version | NM_174060.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | follitropin subunit beta precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M83753.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GQ163481.1, GQ163482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145419, SAMN03145448 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGTCTG TCCAGTTCTG TTTCCTTTTC TGTTGCTGGA GAGCAATCTG CTGCAGAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776485.1 |
CDS | 70..459 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174060.1 |
1 | ATGAAGTCTG TCCAGTTCTG TTTCCTTTTC TGTTGCTGGA GAGCAATCTG CTGCAGAAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage. |
Naturally occurring genetic mutations in the 5'-upstream regulatory region of bovine FSHB generate a novel cis-regulatory element that affects its expression. |
Molecular cloning and sequence analysis of follicle-stimulating hormone beta polypeptide precursor cDNA from the bovine pituitary gland. |
Effects of novel single nucleotide polymorphisms of the FSH beta-subunit gene on semen quality and fertility in bulls. |
A whole-genome assembly of the domestic cow, Bos taurus. |