Gene Symbol | CTSV |
Entrez Gene ID | 281108 |
Full Name | cathepsin V |
Synonyms | CTSL,CTSL1,CTSL2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » CTSV cDNA ORF clone
Gene Symbol | CTSV |
Entrez Gene ID | 281108 |
Full Name | cathepsin V |
Synonyms | CTSL,CTSL1,CTSL2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174032.2 | NP_776457.1 | cathepsin L2 precursor |
Arabidopsis thaliana (thale cress) | AT5G43060 | NP_568620.1 |
Canis lupus familiaris (dog) | CTSL | NP_001239115.1 |
Bos taurus (cattle) | CTSV | NP_776457.1 |
Mus musculus (house mouse) | Ctsl | NP_034114.1 |
Caenorhabditis elegans (roundworm) | cpl-1 | NP_001256718.1 |
Arabidopsis thaliana (thale cress) | AT3G19390 | NP_566633.1 |
Xenopus tropicalis (tropical clawed frog) | ctsv | NP_001004869.1 |
Danio rerio (zebrafish) | ctsla | NP_997749.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011828 | XP_001689282.1 |
Arabidopsis thaliana (thale cress) | RD21 | NP_564497.1 |
Oryza sativa (rice) | Os04g0670500 | NP_001054213.1 |
Oryza sativa (rice) | Os04g0670200 | NP_001054211.2 |
Pan troglodytes (chimpanzee) | CTSL2 | XP_520130.2 |
CTSL2 | XP_002800251.1 | |
Homo sapiens (human) | CTSV | NP_001324.2 |
Canis lupus familiaris (dog) | LOC102156614 | XP_005615836.1 |
Rattus norvegicus (Norway rat) | Ctsl1 | NP_037288.1 |
Gallus gallus (chicken) | CTSL2 | NP_001161481.1 |
Drosophila melanogaster (fruit fly) | Cp1 | NP_523735.2 |
Arabidopsis thaliana (thale cress) | AT3G19400 | NP_566634.2 |
Arabidopsis thaliana (thale cress) | AT3G43960 | NP_566867.1 |
Cathepsins S, B and L with aminopeptidases display ?-secretase activity associated with the pathogenesis of Alzheimer's disease.
Schechter I, Ziv E
Biological chemistry392(6)555-69(2011 Apr)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion.
Hwang SR, Garza C, Mosier C, Toneff T, Wunderlich E, Goldsmith P, Hook V
The Journal of biological chemistry282(13)9556-63(2007 Mar)
Characterization of 954 bovine full-CDS cDNA sequences.
Harhay GP, Sonstegard TS, Keele JW, Heaton MP, Clawson ML, Snelling WM, Wiedmann RT, Van Tassell CP, Smith TP
BMC genomics6166(2005 Nov)
Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.
Yasothornsrikul S, Greenbaum D, Medzihradszky KF, Toneff T, Bundey R, Miller R, Schilling B, Petermann I, Dehnert J, Logvinova A, Goldsmith P, Neveu JM, Lane WS, Gibson B, Reinheckel T, Peters C, Bogyo M, Hook V
Proceedings of the National Academy of Sciences of the United States of America100(16)9590-5(2003 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The cathepsin L deserves further evaluation as therapeutic targets to develop disease modifying drugs to treat Alzheimer's disease.
Title: Cathepsins S, B and L with aminopeptidases display ?-secretase activity associated with the pathogenesis of Alzheimer's disease.
Secretory vesicle function of cathepsin L for biosynthesis of active enkephalin opioid peptide contrasts with its function in lysosomes for protein degradation.
Title: Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion.
Cathepsin L has an previously uncharacterized biological role in the production of [Met]enkephalin, an endogenous peptide neurotransmitter
Title: Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.
The following CTSV gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CTSV cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa41621 | |
Clone ID Related Accession (Same CDS sequence) | NM_174032.2 | |
Accession Version | NM_174032.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | cathepsin L2 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X91755.1. On Jun 3, 2003 this sequence version replaced NM_174032.1. ##Evidence-Data-START## CDS exon combination :: X91755.1, BC151425.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMN03145420 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATCCTT CATTCTTCCT GACTGTCCTT TGCTTGGGAG TAGCATCAGC TGCTCCCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776457.1 |
CDS | 88..1092 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174032.2 |
1 | ATGAATCCTT CATTCTTCCT GACTGTCCTT TGCTTGGGAG TAGCATCAGC TGCTCCCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cathepsins S, B and L with aminopeptidases display ?-secretase activity associated with the pathogenesis of Alzheimer's disease. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Cathepsin L expression is directed to secretory vesicles for enkephalin neuropeptide biosynthesis and secretion. |
Characterization of 954 bovine full-CDS cDNA sequences. |
Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter. |