Gene Symbol | PRL |
Entrez Gene ID | 280901 |
Full Name | prolactin |
Synonyms | GHA1,Prol |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » PRL cDNA ORF clone
Gene Symbol | PRL |
Entrez Gene ID | 280901 |
Full Name | prolactin |
Synonyms | GHA1,Prol |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_173953.2 | NP_776378.2 | prolactin precursor |
Rattus norvegicus (Norway rat) | Prl | NP_036761.1 |
Gallus gallus (chicken) | PRL | NP_990797.2 |
Canis lupus familiaris (dog) | PRL | NP_001008276.2 |
Xenopus tropicalis (tropical clawed frog) | prl.1 | NP_001093699.1 |
Homo sapiens (human) | PRL | NP_001157030.1 |
Pan troglodytes (chimpanzee) | PRL | XP_518264.1 |
PRL | NP_001040593.1 | |
Bos taurus (cattle) | PRL | NP_776378.2 |
Mus musculus (house mouse) | Prl | NP_035294.2 |
Curated eutherian third party data gene data sets.
Premzl M
Data in brief6208-13(2016 Mar)
Non-classical effects of prolactin on the innate immune response of bovine mammary epithelial cells: Implications during Staphylococcus aureus internalization.
Medina-Estrada I, Alva-Murillo N, L?pez-Meza JE, Ochoa-Zarzosa A
Microbial pathogenesis8943-53(2015 Dec)
Third party data gene data set of eutherian growth hormone genes.
Premzl M
Genomics data6166-9(2015 Dec)
Identification of bovine prolactin in seminal fluid, and expression and localization of the prolactin receptor and prolactin-inducible protein in the testis and epididymis of bulls exposed to ergot alkaloids.
Pratt SL, Calcatera SM, Stowe HM, Dimmick MA, Schrick FN, Duckett SK, Andrae JG
Theriogenology83(4)662-9(2015 Mar)
Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle.
Littlejohn MD, Henty KM, Tiplady K, Johnson T, Harland C, Lopdell T, Sherlock RG, Li W, Lukefahr SD, Shanks BC, Garrick DJ, Snell RG, Spelman RJ, Davis SR
Nature communications55861(2014 12)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Taken together, these results support novel functions of prolactin as a modulator of the innate immune response that do not involve the classical prolactin pathway.
Title: Non-classical effects of prolactin on the innate immune response of bovine mammary epithelial cells: Implications during Staphylococcus aureus internalization.
The presence and localization of prolactin receptor are consistent with expression data reported for other species, and the presence of PIP and prolactin in seminal fluid is consistent with data generated in humans.
Title: Identification of bovine prolactin in seminal fluid, and expression and localization of the prolactin receptor and prolactin-inducible protein in the testis and epididymis of bulls exposed to ergot alkaloids.
Functionally reciprocal mutations of the prolactin signaling pathway define hairy and slick cattle.
Title: Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle.
The single nucleotide polymorphism rs42646708 of cattle XKR4 was significantly associated with serum prolactin concentrations and explained 2.45% of the phenotypic variation.
Title: A polymorphism in XKR4 is significantly associated with serum prolactin concentrations in beef cows grazing tall fescue.
this study identifies a biochemical mechanism for the regulation of SCFAs on bovine GH and PRL gene transcription in dairy cow anterior pituitary cells
Title: Short-chain fatty acids inhibit growth hormone and prolactin gene transcription via cAMP/PKA/CREB signaling pathway in dairy cow anterior pituitary cells.
The following PRL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01413 | |
Clone ID Related Accession (Same CDS sequence) | NM_173953.2 | |
Accession Version | NM_173953.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Bos taurus(cattle) | |
Product | prolactin precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from V00112.1. On Apr 28, 2004 this sequence version replaced NM_173953.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: V00112.1, BC148124.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145448, SAMN03145451 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACAGCA AAGGTTCGTC GCAGAAAGGG TCCCGCCTGC TCCTGCTGCT GGTGGTGTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776378.2 |
CDS | 68..757 |
Translation |
Target ORF information:
Target ORF information:
|
NM_173953.2 |
1 | ATGGACAGCA AAGGTTCGTC GCAGAAAGGG TCCCGCCTGC TCCTGCTGCT GGTGGTGTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Curated eutherian third party data gene data sets. |
Non-classical effects of prolactin on the innate immune response of bovine mammary epithelial cells: Implications during Staphylococcus aureus internalization. |
Third party data gene data set of eutherian growth hormone genes. |
Identification of bovine prolactin in seminal fluid, and expression and localization of the prolactin receptor and prolactin-inducible protein in the testis and epididymis of bulls exposed to ergot alkaloids. |
Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle. |