Gene Symbol | DEFB3 |
Entrez Gene ID | 101906662 |
Full Name | defensin beta 3 |
Synonyms | BNBD-3,BNBD-6,BNDB-3,BNDB-6,BNDB3,DEFB103A,DEFB2,DEFB6,bnbd3,defb405 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » DEFB3 cDNA ORF clone
Gene Symbol | DEFB3 |
Entrez Gene ID | 101906662 |
Full Name | defensin beta 3 |
Synonyms | BNBD-3,BNBD-6,BNDB-3,BNDB-6,BNDB3,DEFB103A,DEFB2,DEFB6,bnbd3,defb405 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_001282581.1 | NP_001269510.1 | beta-defensin 3 precursor |
Multiple ?-defensin genes are upregulated by the vitamin D pathway in cattle.
Merriman KE, Kweh MF, Powell JL, Lippolis JD, Nelson CD
The Journal of steroid biochemistry and molecular biology154120-9(2015 Nov)
The synthetic peptides bovine enteric ?-defensin (EBD), bovine neutrophil ?-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells.
Mackenzie-Dyck S, Attah-Poku S, Juillard V, Babiuk LA, van Drunen Littel-van den Hurk S
Veterinary immunology and immunopathology143(1-2)87-107(2011 Sep)
Bovine beta-defensins: identification and characterization of novel bovine beta-defensin genes and their expression in mammary gland tissue.
Roosen S, Exner K, Paul S, Schr?der JM, Kalm E, Looft C
Mammalian genome : official journal of the International Mammalian Genome Society15(10)834-42(2004 Oct)
Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection.
Tarver AP, Clark DP, Diamond G, Russell JP, Erdjument-Bromage H, Tempst P, Cohen KS, Jones DE, Sweeney RW, Wines M, Hwang S, Bevins CL
Infection and immunity66(3)1045-56(1998 Mar)
Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
Selsted ME, Tang YQ, Morris WL, McGuire PA, Novotny MJ, Smith W, Henschen AH, Cullor JS
The Journal of biological chemistry268(9)6641-8(1993 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Bovine DEFB3 gene expression is upregulated by vitamin D and toll-like receptor signaling.
Title: Multiple ?-defensin genes are upregulated by the vitamin D pathway in cattle.
The synthetic peptides bovine enteric beta-defensin (EBD), bovine neutrophil beta-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.
Title: The synthetic peptides bovine enteric ?-defensin (EBD), bovine neutrophil ?-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells.
Beta-defensin antimicrobial peptides DEFB2 and DEFB3.
Title: Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
The following DEFB3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DEFB3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa00720 | |
Clone ID Related Accession (Same CDS sequence) | NM_001282581.1 | |
Accession Version | NM_001282581.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 195bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-13 | |
Organism | Bos taurus(cattle) | |
Product | beta-defensin 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DAAA02059846.1. On Sep 14, 2013 this sequence version replaced XR_240312.1. Sequence Note: The RefSeq transcript was derived from the reference genome assembly. The genomic coordinates were determined from alignments. ##Evidence-Data-START## Transcript exon combination :: EH151999.1, DV805786.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGAGGCTCC ATCACCTGCT CCTCGCACTC CTCTTCCTGG TCCTGTCTGC TGGGTCAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001269510.1 |
CDS | 210..404 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001282581.1 |
1 | ATGAGGCTCC ATCACCTGCT CCTCGCACTC CTCTTCCTGG TCCTGTCTGC TGGGTCAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Multiple ?-defensin genes are upregulated by the vitamin D pathway in cattle. |
The synthetic peptides bovine enteric ?-defensin (EBD), bovine neutrophil ?-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells. |
Bovine beta-defensins: identification and characterization of novel bovine beta-defensin genes and their expression in mammary gland tissue. |
Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection. |
Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. |