NPC1 cDNA ORF clone, Capra hircus(goat)

Gene
Clones
gRNAs

Summary

Gene Symbol	NPC1
Entrez Gene ID	102189363
Full Name	NPC intracellular cholesterol transporter 1
Gene Type	protein-coding
Organism	Capra hircus(goat)

mRNA and Protein(s)

mRNA	Protein	Name
XM_018039477.1	XP_017894966.1	LOW QUALITY PROTEIN: Niemann-Pick C1 protein

Pathways from BioSystems
Gene Ontology

The following NPC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NPC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCa139747	XM_018039477.1 Latest version!	Capra hircus NPC intracellular cholesterol transporter 1 (NPC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$713.30 $1019.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NPC1 ( XM_018039477.1 ) cDNA ORF clone, Capra hircus(goat) -> XP_017894966.1 Capra hircus NPC intracellular cholesterol transporter 1 (NPC1), mRNA.

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CloneID	OCa139747
Clone ID Related Accession (Same CDS sequence)	XM_018039477.1
Accession Version	XM_018039477.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3834bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-09-07
Organism	Capra hircus(goat)
Product	LOW QUALITY PROTEIN: Niemann-Pick C1 protein
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_030831.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Capra hircus Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END##

ATGAGCGTGC GCGGCCCAGC CCTCGGCCTC CTCCTGCTGC TCTTCTGCCC GGCGCAGGTA 
TTTTCACAAT CCTGCATTTG GTATGGGGAG TGTGGAATCG CATCTGGAGA TAAGAGATAC 
AACTGCAGAT ATTCTGGGCC ACCAAATCCA TTGCCACATA ATGGCTATGA CCTAGTGCAG 
GAGCTCTGTC CAGGGTTCTT CTTTGGCGAA GTCAGGCTTT GCTGTGATGT CCAGCAGCTT 
CACACACTGA AAGACAACCT GCAGCTGCCT CTGCAGTTTC TGTCCAGATG TCCATCCTGT 
TTTTATAACC TAGTGAACCT GTTTTGTGAG CTGACATGTA GCCCTCGACA AAGTCAGTTT 
CTGAATGTTA CAGTGGCTGA AGATTATGTT GATCCTACTA CGAATGAGAC GAGAACAAAT 
GTAAAAGAAT TACAGTACTA TGTTGGAGAG CGTTTTGCCA ATGCCATGTA CAACGCCTGC 
CGGGATGTGG AGGCCCCCTC GAGCAACGAG AAGGCCCTGG GGCTGCTGTG TGGGCGTGAG 
GCCAGCGCCT GCAACGCTAC CAACTGGATC GAGTACATGT TCAACAAGGA CAATGGCCAG 
GCGCCCTTCA CCATCACCCC TGTCTTTTCA GATCTTCCGA CCCATGGGAT GCAGCCCATG 
AACAATGCCA CCAAGGGCTG TGACGAGTCG GTGGACGAGG TCACGGGGCC GTGCAGCTGC 
CAGGACTGCT CGGCTGTCTG CGGCCCCAAG CCCCAGCCCC CGCCCCCTCC CGTTCCCTGG 
AGAATCCTGG GTCTCGACGC CATGTACGTC ATCATGTGGA GCACCTACAT GGCTTTCCTG 
CTCGTGTTTT TTGGAGCGTT CTTTGCTGTG TGGTGCTACA GAAAACGGTA TTTTGTCTCT 
GAGTTTACCC CCATTGATGG CAATATACCT TTCNTTATAA ACGCTAGTGA CAAAGGGGGG 
CCAACCTGCT GTGACCCTCT GGGCGCCGCC TTGGAGGCCC ATCTGCGGCG GCTCTTCGAA 
CGGTGGGGTT CCTTCTGTGT GAGGTACCCC GGCTGTGTCG TGTTCTTCTC CGTGGCCTTC 
ATCGCCACCT GTTCCTCAGG CCTGGTGTTC ATCCAGGTCA CAACCGACCC GGTGGACCTC 
TGGTCGGCCC CCGGCAGCCA GGCCCGCCAG GAGAAGGAGT ACTTCGACAC GCACTTCGGG 
CCCTTCTTCC GCACCGAGCA GCTCATCATC CGGGCCCCCA ACACCCCGCC GCACACATAC 
GAGCCCTACC CCTCCGGAGC CGACGTGCCC TTCGGGCCTC CCCTCGCCAT AGACATTCTG 
CACCAGGTCC TTGACTTACA AACCGCCATC GAGAGCATCA CTGCTTCTTA CAACAACGAG 
ACTGTGACCC TGCGGGACAT CTGTGTGGCG CCCCTCTCGC CATACAACCA GAACTGCACC 
GTCCTGAGCG TGCTGAATTA CTTCCAGAAC AGCCACTCCG TTCTGGACCA TCAGGTCGGG 
GACGACTTCT TTGTGTACGC GGATTACCAC ACGCACTTCC TCTACTGTGT CCGGGCTCCT 
GCTTCCCTGA ATGACACCAG TTTGCTCCAC GATCCTTGCC TGGGGACGTT TGGTGGCCCA 
GTGTTTCCAT GGCTTGTGCT TGGAGGCTAT GATGATCAAA ACTACAATAA CGCCACAGCC 
CTTGTGATCA CTTTTCCTGT CAATAATTAC TATAACGATA CAGAGAAGCT CCAGAGGGCC 
CAGGCCTGGG AAAGAGAGTT CATTAATTTT GTGAAAAACT ACGAGAATCC CAATCTGACC 
ATTTCTTTTA AGGCTGAACG AAGCATTGAA GATGAACTAA ACCGTGAAAG TAACAGTGAC 
GTCTTCACTG TTCTGATCAG CTATGGCGTC ATGTTTTTAT ATATTTCCAT AGCCTTGGGG 
CATATCAAAA GCTGTCGCAG GCTTCTGGTG GATTCGAAAA TCTCCCTGGG CATTGCCGGG 
GTCCTGATTG TGTTGAGCTC AGTGGCCTGC TCCTTGGGCA TCTTCAGCTA CATCGGGGTG 
CCCCTGACCC TCATTGTGAT CGAAGTCATC CCATTCCTCG TGCTGGCTGT GGGGGTGGAC 
AACATCTTCA TCCTGGTCCA GACCTACCAG AGAGATGAAC GTCTTCAAGG GGAAACCCTG 
GACCAACAGG TGGGCCGGGT CCTGGGAGAA GTGGCTCCCA GCATGTTCCT CTCATCCTTC 
GCAGAGACGG TAGCGTTTTT CTTAGGAGGC CTGTCCGTGA TGCCGGCCGT GCACACGTTC 
TCCCTCTTCG CGGGCATGGC GGTCCTCATC GACTTCCTCC TGCAGATCAC CTGCTTCGTG 
AGCCTCCTGG GCTTGGACAT TAAGCGGCAA GAGAAGAACC AGCTGGACGT TCTCTGCTGT 
GTCAAGGGGG CGGCAGACGA CACAGGCATC CAGGCCTCCG AGAGCTGCTT GTTCCGCTTC 
TTCAGAAACT CCTATGCCCC GCTTCTGCTC AAGGACTGGA TGCGGCCCCT CGTGGTAGCA 
GTATTTGTGG GTGTGCTGTC GTTCAGCATC GCAGTCCTGA ACAAAGTAGA GATCGGATTG 
GATCAGTCTC TTTCAATGCC GGATGACTCC TACATGACGG ATTACTTCCA GTCCCTGAAT 
CAGTACCTGC ACGCAGGCCC ACCTGTGTAC TTCGTGCTGG AGGAGGGCCA CGACTACACG 
TCCACAAAGG GTCAGAACAT GGTGTGTGGG GGCCTCGGCT GCAACAACGA CTCGCTGGTG 
CAGCAGGTCT TCACGGCCGC CCAGCTGGAC AACTACACCC GGATAGGCTT TGCCCCGTCG 
TCCTGGATTG ACGATTACTT TGACTGGGTC AAGCCTCAAT CATCTTGCTG TCGCATCTAC 
AACAGCACGG AGCAGTTCTG CAATGCGTCG GTGGTCGACC CTGCCTGTGT CCGCTGCCGG 
CCGCTGACTC CGGAGGGCAA GCAGAGACCT CAGGGCGCAG ACTTCATGAG GTTCCTGCCC 
ATGTTCCTCT CCGACAACCC GAACCCCAAG TGTGGCAAAG GGGGACATGC TGCCTACAGC 
GCGGCCGTCA ACATCCTGGA CAACGGCACG AGCGTGGGAG CCACATATTT CATGACCTAC 
CACACGGTGC TGCAGACCTC GGCTGACTTC ATCGATGCCA TGGAGAAGGC CCGCCTCATC 
GCCAACAACA TCACCAGGAC CATGAACCAG CAAGGGGGTG ATCACCGGGT GTTCCCATAC 
AGCGTGTTCT ACGTCTTCTA TGAGCAGTAC CTGACCATGA TTGACGACAC CGTCTTCAAC 
CTCGGCGTGT CCCTGGGCGC CATCTTCCTG GTGGCCGTGG GCCTCCTGGG CTGTGAGCTG 
TGGGCCGCGG GCATCATGTG CGCCACCATC GCCATGATCC TCGTCAACAT GTTCGGCGTC 
ATGTGGCTGT GGGGCATCAG CCTGAACGCG GTTTCTCTGG TCAACCTGGT CATGAGCTGC 
GGCATCTCCG TGGAGTTCTG TAGCCACATC ACGAGGGCGT TCACGGTGAG CACAAAGGGC 
AGCCGCGTGG AGCGGGCAGA GGAGGCGCTC TCCCACATGG GCAGCTCTGT ATTCAGTGGA 
ATCACACTAA CGAAATTTGG AGGCATTATC GTGTTGGCCT TTGCCAAATC TCAAATTTTC 
CAGATATTTT ACTTCAGGAT GTATTTAGCT ATGGTCTTAC TGGGAGCCAG TCATGGACTA 
ATATTCCTCC CTGTCTTACT CAGTTACATA GGACCATCAA TAAATAAAGC CAAAAGTCTG 
ACCACGCAGC AGCGATACAG AGGTACAGAG CGAGAACAGC TCCTCAACTT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017894966.1
CDS	149..3982
Translation	MSVRGPALGLLLLLFCPAQVFSQSCIWYGECGIASGDKRYNCRYSGPPNPLPHNGYDLVQELCPGFFFGEVRLCCDVQQLHTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTVAEDYVDPTTNETRTNVKELQYYVGERFANAMYNACRDVEAPSSNEKALGLLCGREASACNATNWIEYMFNKDNGQAPFTITPVFSDLPTHGMQPMNNATKGCDESVDEVTGPCSCQDCSAVCGPKPQPPPPPVPWRILGLDAMYVIMWSTYMAFLLVFFGAFFAVWCYRKRYFVSEFTPIDGNIPFnullINASDKGGPTCCDPLGAALEAHLRRLFERWGSFCVRYPGCVVFFSVAFIATCSSGLVFIQVTTDPVDLWSAPGSQARQEKEYFDTHFGPFFRTEQLIIRAPNTPPHTYEPYPSGADVPFGPPLAIDILHQVLDLQTAIESITASYNNETVTLRDICVAPLSPYNQNCTVLSVLNYFQNSHSVLDHQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEREFINFVKNYENPNLTISFKAERSIEDELNRESNSDVFTVLISYGVMFLYISIALGHIKSCRRLLVDSKISLGIAGVLIVLSSVACSLGIFSYIGVPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQGETLDQQVGRVLGEVAPSMFLSSFAETVAFFLGGLSVMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNQLDVLCCVKGAADDTGIQASESCLFRFFRNSYAPLLLKDWMRPLVVAVFVGVLSFSIAVLNKVEIGLDQSLSMPDDSYMTDYFQSLNQYLHAGPPVYFVLEEGHDYTSTKGQNMVCGGLGCNNDSLVQQVFTAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRIYNSTEQFCNASVVDPACVRCRPLTPEGKQRPQGADFMRFLPMFLSDNPNPKCGKGGHAAYSAAVNILDNGTSVGATYFMTYHTVLQTSADFIDAMEKARLIANNITRTMNQQGGDHRVFPYSVFYVFYEQYLTMIDDTVFNLGVSLGAIFLVAVGLLGCELWAAGIMCATIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSTKGSRVERAEEALSHMGSSVFSGITLTKFGGIIVLAFAKSQIFQIFYFRMYLAMVLLGASHGLIFLPVLLSYIGPSINKAKSLTTQQRYRGTEREQLLNF

Target ORF information:

RefSeq Version	XM_018039477.1
Organism	Capra hircus(goat)
Definition	Capra hircus NPC intracellular cholesterol transporter 1 (NPC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_018039477.1

ORF Insert Sequence:

ATGAGCGTGC GCGGCCCAGC CCTCGGCCTC CTCCTGCTGC TCTTCTGCCC GGCGCAGGTA 
TTTTCACAAT CCTGCATTTG GTATGGGGAG TGTGGAATCG CATCTGGAGA TAAGAGATAC 
AACTGCAGAT ATTCTGGGCC ACCAAATCCA TTGCCACATA ATGGCTATGA CCTAGTGCAG 
GAGCTCTGTC CAGGGTTCTT CTTTGGCGAA GTCAGGCTTT GCTGTGATGT CCAGCAGCTT 
CACACACTGA AAGACAACCT GCAGCTGCCT CTGCAGTTTC TGTCCAGATG TCCATCCTGT 
TTTTATAACC TAGTGAACCT GTTTTGTGAG CTGACATGTA GCCCTCGACA AAGTCAGTTT 
CTGAATGTTA CAGTGGCTGA AGATTATGTT GATCCTACTA CGAATGAGAC GAGAACAAAT 
GTAAAAGAAT TACAGTACTA TGTTGGAGAG CGTTTTGCCA ATGCCATGTA CAACGCCTGC 
CGGGATGTGG AGGCCCCCTC GAGCAACGAG AAGGCCCTGG GGCTGCTGTG TGGGCGTGAG 
GCCAGCGCCT GCAACGCTAC CAACTGGATC GAGTACATGT TCAACAAGGA CAATGGCCAG 
GCGCCCTTCA CCATCACCCC TGTCTTTTCA GATCTTCCGA CCCATGGGAT GCAGCCCATG 
AACAATGCCA CCAAGGGCTG TGACGAGTCG GTGGACGAGG TCACGGGGCC GTGCAGCTGC 
CAGGACTGCT CGGCTGTCTG CGGCCCCAAG CCCCAGCCCC CGCCCCCTCC CGTTCCCTGG 
AGAATCCTGG GTCTCGACGC CATGTACGTC ATCATGTGGA GCACCTACAT GGCTTTCCTG 
CTCGTGTTTT TTGGAGCGTT CTTTGCTGTG TGGTGCTACA GAAAACGGTA TTTTGTCTCT 
GAGTTTACCC CCATTGATGG CAATATACCT TTCNTTATAA ACGCTAGTGA CAAAGGGGGG 
CCAACCTGCT GTGACCCTCT GGGCGCCGCC TTGGAGGCCC ATCTGCGGCG GCTCTTCGAA 
CGGTGGGGTT CCTTCTGTGT GAGGTACCCC GGCTGTGTCG TGTTCTTCTC CGTGGCCTTC 
ATCGCCACCT GTTCCTCAGG CCTGGTGTTC ATCCAGGTCA CAACCGACCC GGTGGACCTC 
TGGTCGGCCC CCGGCAGCCA GGCCCGCCAG GAGAAGGAGT ACTTCGACAC GCACTTCGGG 
CCCTTCTTCC GCACCGAGCA GCTCATCATC CGGGCCCCCA ACACCCCGCC GCACACATAC 
GAGCCCTACC CCTCCGGAGC CGACGTGCCC TTCGGGCCTC CCCTCGCCAT AGACATTCTG 
CACCAGGTCC TTGACTTACA AACCGCCATC GAGAGCATCA CTGCTTCTTA CAACAACGAG 
ACTGTGACCC TGCGGGACAT CTGTGTGGCG CCCCTCTCGC CATACAACCA GAACTGCACC 
GTCCTGAGCG TGCTGAATTA CTTCCAGAAC AGCCACTCCG TTCTGGACCA TCAGGTCGGG 
GACGACTTCT TTGTGTACGC GGATTACCAC ACGCACTTCC TCTACTGTGT CCGGGCTCCT 
GCTTCCCTGA ATGACACCAG TTTGCTCCAC GATCCTTGCC TGGGGACGTT TGGTGGCCCA 
GTGTTTCCAT GGCTTGTGCT TGGAGGCTAT GATGATCAAA ACTACAATAA CGCCACAGCC 
CTTGTGATCA CTTTTCCTGT CAATAATTAC TATAACGATA CAGAGAAGCT CCAGAGGGCC 
CAGGCCTGGG AAAGAGAGTT CATTAATTTT GTGAAAAACT ACGAGAATCC CAATCTGACC 
ATTTCTTTTA AGGCTGAACG AAGCATTGAA GATGAACTAA ACCGTGAAAG TAACAGTGAC 
GTCTTCACTG TTCTGATCAG CTATGGCGTC ATGTTTTTAT ATATTTCCAT AGCCTTGGGG 
CATATCAAAA GCTGTCGCAG GCTTCTGGTG GATTCGAAAA TCTCCCTGGG CATTGCCGGG 
GTCCTGATTG TGTTGAGCTC AGTGGCCTGC TCCTTGGGCA TCTTCAGCTA CATCGGGGTG 
CCCCTGACCC TCATTGTGAT CGAAGTCATC CCATTCCTCG TGCTGGCTGT GGGGGTGGAC 
AACATCTTCA TCCTGGTCCA GACCTACCAG AGAGATGAAC GTCTTCAAGG GGAAACCCTG 
GACCAACAGG TGGGCCGGGT CCTGGGAGAA GTGGCTCCCA GCATGTTCCT CTCATCCTTC 
GCAGAGACGG TAGCGTTTTT CTTAGGAGGC CTGTCCGTGA TGCCGGCCGT GCACACGTTC 
TCCCTCTTCG CGGGCATGGC GGTCCTCATC GACTTCCTCC TGCAGATCAC CTGCTTCGTG 
AGCCTCCTGG GCTTGGACAT TAAGCGGCAA GAGAAGAACC AGCTGGACGT TCTCTGCTGT 
GTCAAGGGGG CGGCAGACGA CACAGGCATC CAGGCCTCCG AGAGCTGCTT GTTCCGCTTC 
TTCAGAAACT CCTATGCCCC GCTTCTGCTC AAGGACTGGA TGCGGCCCCT CGTGGTAGCA 
GTATTTGTGG GTGTGCTGTC GTTCAGCATC GCAGTCCTGA ACAAAGTAGA GATCGGATTG 
GATCAGTCTC TTTCAATGCC GGATGACTCC TACATGACGG ATTACTTCCA GTCCCTGAAT 
CAGTACCTGC ACGCAGGCCC ACCTGTGTAC TTCGTGCTGG AGGAGGGCCA CGACTACACG 
TCCACAAAGG GTCAGAACAT GGTGTGTGGG GGCCTCGGCT GCAACAACGA CTCGCTGGTG 
CAGCAGGTCT TCACGGCCGC CCAGCTGGAC AACTACACCC GGATAGGCTT TGCCCCGTCG 
TCCTGGATTG ACGATTACTT TGACTGGGTC AAGCCTCAAT CATCTTGCTG TCGCATCTAC 
AACAGCACGG AGCAGTTCTG CAATGCGTCG GTGGTCGACC CTGCCTGTGT CCGCTGCCGG 
CCGCTGACTC CGGAGGGCAA GCAGAGACCT CAGGGCGCAG ACTTCATGAG GTTCCTGCCC 
ATGTTCCTCT CCGACAACCC GAACCCCAAG TGTGGCAAAG GGGGACATGC TGCCTACAGC 
GCGGCCGTCA ACATCCTGGA CAACGGCACG AGCGTGGGAG CCACATATTT CATGACCTAC 
CACACGGTGC TGCAGACCTC GGCTGACTTC ATCGATGCCA TGGAGAAGGC CCGCCTCATC 
GCCAACAACA TCACCAGGAC CATGAACCAG CAAGGGGGTG ATCACCGGGT GTTCCCATAC 
AGCGTGTTCT ACGTCTTCTA TGAGCAGTAC CTGACCATGA TTGACGACAC CGTCTTCAAC 
CTCGGCGTGT CCCTGGGCGC CATCTTCCTG GTGGCCGTGG GCCTCCTGGG CTGTGAGCTG 
TGGGCCGCGG GCATCATGTG CGCCACCATC GCCATGATCC TCGTCAACAT GTTCGGCGTC 
ATGTGGCTGT GGGGCATCAG CCTGAACGCG GTTTCTCTGG TCAACCTGGT CATGAGCTGC 
GGCATCTCCG TGGAGTTCTG TAGCCACATC ACGAGGGCGT TCACGGTGAG CACAAAGGGC 
AGCCGCGTGG AGCGGGCAGA GGAGGCGCTC TCCCACATGG GCAGCTCTGT ATTCAGTGGA 
ATCACACTAA CGAAATTTGG AGGCATTATC GTGTTGGCCT TTGCCAAATC TCAAATTTTC 
CAGATATTTT ACTTCAGGAT GTATTTAGCT ATGGTCTTAC TGGGAGCCAG TCATGGACTA 
ATATTCCTCC CTGTCTTACT CAGTTACATA GGACCATCAA TAAATAAAGC CAAAAGTCTG 
ACCACGCAGC AGCGATACAG AGGTACAGAG CGAGAACAGC TCCTCAACTT CTAG