ORF » Species Summary » Canis lupus familiaris » Reactome

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Canis lupus familiaris (dog)

Browse by Letter Index, Genomic Locus


Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Recycling of eIF2:GDP
L13a-mediated translational silencing of Ceruloplasmin expression Eukaryotic Translation Elongation
Post-translational protein modification Gamma carboxylation, hypusine formation and arylsulfatase activation
Hypusine synthesis from eIF5A-lysine Sialic acid metabolism
Reactions specific to the hybrid N-glycan synthesis pathway Termination of O-glycan biosynthesis
Processing and activation of SUMO SUMO is transferred from E1 to E2 (UBE2I, UBC9)
Mitochondrial protein import Incretin synthesis, secretion, and inactivation
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Unfolded Protein Response (UPR)
Surfactant metabolism Programmed Cell Death
Caspase activation via extrinsic apoptotic signalling pathway Intrinsic Pathway for Apoptosis
Activation of BH3-only proteins Activation of BMF and translocation to mitochondria
Activation and oligomerization of BAK protein Activation of caspases through apoptosome-mediated cleavage
Apoptotic execution phase Apoptotic cleavage of cell adhesion proteins
Regulation of necroptotic cell death Platelet homeostasis
Platelet Adhesion to exposed collagen Platelet activation, signaling and aggregation
Platelet Aggregation (Plug Formation) GRB2:SOS provides linkage to MAPK signaling for Integrins
Tie2 Signaling Vesicle-mediated transport
trans-Golgi Network Vesicle Budding Golgi Associated Vesicle Biogenesis
Gap junction trafficking and regulation Transport of connexons to the plasma membrane
Formation of annular gap junctions Endosomal Sorting Complex Required For Transport (ESCRT)
Scavenging by Class A Receptors Scavenging by Class H Receptors
Cell-extracellular matrix interactions DSCAM interactions
Transmission across Chemical Synapses Acetylcholine Binding And Downstream Events
Presynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII
GABA A (rho) receptor activation Ca2+ activated K+ channels
Phase 4 - resting membrane potential HDACs deacetylate histones
GAB1 signalosome EGFR downregulation
FGFR1 ligand binding and activation FGFR1b ligand binding and activation
PI-3K cascade:FGFR1 Downstream signaling of activated FGFR2
Signaling by FGFR4 SHC-mediated cascade:FGFR4
PI-3K cascade:FGFR4 PKB-mediated events
NRAGE signals death through JNK p75NTR regulates axonogenesis
Axonal growth inhibition (RHOA activation) TRKA activation by NGF
Signalling to RAS p38MAPK events
Signalling to p38 via RIT and RIN Prolonged ERK activation events
ARMS-mediated activation Signalling to ERK5
Neurophilin interactions with VEGF and VEGFR Signaling by SCF-KIT
GRB2 events in ERBB2 signaling GRB7 events in ERBB2 signaling
Downregulation of ERBB2:ERBB3 signaling Signaling by ERBB4
MAPK1/MAPK3 signaling RAF-independent MAPK1/3 activation
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 RHO GTPases regulate CFTR trafficking
RHO GTPases Activate NADPH Oxidases Signaling by TGF-beta Receptor Complex
TGF-beta receptor signaling activates SMADs TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
Downregulation of SMAD2/3:SMAD4 transcriptional activity Signaling by NOTCH
Signaling by NOTCH4 GPCR ligand binding
Orexin and neuropeptides FF and QRFP bind to their respective receptors Formyl peptide receptors bind formyl peptides and many other ligands
Relaxin receptors Hydroxycarboxylic acid-binding receptors
G alpha (q) signalling events Opioid Signalling
Gastrin-CREB signalling pathway via PKC and MAPK Beta-catenin phosphorylation cascade
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