ORF » Species Summary » Canis lupus familiaris » Reactome

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Canis lupus familiaris (dog)

Browse by Letter Index, Genomic Locus


Miscellaneous substrates FMO oxidises nucleophiles
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB Glucuronidation
Aflatoxin activation and detoxification Abacavir transport and metabolism
Abacavir metabolism Reversible hydration of carbon dioxide
Mitochondrial translation elongation Cargo trafficking to the periciliary membrane
Trafficking of myristoylated proteins to the cilium Base Excision Repair
Depurination Resolution of Abasic Sites (AP sites)
Resolution of AP sites via the single-nucleotide replacement pathway Abasic sugar-phosphate removal via the single-nucleotide replacement pathway
Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH
Translesion synthesis by POLK DNA Double-Strand Break Repair
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks HDR through Homologous Recombination (HRR)
Nucleotide Excision Repair DNA Damage Recognition in GG-NER
Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
ABC transporters in lipid homeostasis Transport of inorganic cations/anions and amino acids/oligopeptides
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Facilitative Na+-independent glucose transporters
Inositol transporters Zinc efflux and compartmentalization by the SLC30 family
Na+/Cl- dependent neurotransmitter transporters Vasopressin regulates renal water homeostasis via Aquaporins
Ligand-gated ion channel transport Regulation of Hypoxia-inducible Factor (HIF) by oxygen
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oncogene Induced Senescence
DNA Damage/Telomere Stress Induced Senescence Autodegradation of the E3 ubiquitin ligase COP1
G2/M Checkpoints G2/M DNA damage checkpoint
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Inactivation of APC/C via direct inhibition of the APC/C complex
Activation of the pre-replicative complex Orc1 removal from chromatin
Unwinding of DNA Establishment of Sister Chromatid Cohesion
Loss of Nlp from mitotic centrosomes M Phase
Golgi Cisternae Pericentriolar Stack Reorganization Clearance of Nuclear Envelope Membranes from Chromatin
Mitotic Prometaphase Assembly of the pre-replicative complex
Phosphorylation of Emi1 Phosphorylation of the APC/C
Nucleosome assembly Removal of the Flap Intermediate from the C-strand
Generation of second messenger molecules CD28 co-stimulation
PD-1 signaling Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
AKT phosphorylates targets in the cytosol Class I MHC mediated antigen processing & presentation
Cross-presentation of soluble exogenous antigens (endosomes) Trafficking and processing of endosomal TLR
TAK1 activates NFkB by phosphorylation and activation of IKKs complex MAP3K8 (TPL2)-dependent MAPK1/3 activation
ERK/MAPK targets Toll Like Receptor 5 (TLR5) Cascade
MyD88 dependent cascade initiated on endosome TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Complement cascade TRAF3-dependent IRF activation pathway
TRAF6 mediated NF-kB activation Defensins
STING mediated induction of host immune responses Role of phospholipids in phagocytosis
RAF activation Negative regulation of MAPK pathway
Negative feedback regulation of MAPK pathway PKA activation
C-type lectin receptors (CLRs) CLEC7A/inflammasome pathway
Interferon Signaling Interferon alpha/beta signaling
Interleukin receptor SHC signaling IL-6-type cytokine receptor ligand interactions
Interleukin-7 signaling TNFs bind their physiological receptors
Sema4D induced cell migration and growth-cone collapse Other semaphorin interactions
NCAM1 interactions DCC mediated attractive signaling
EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells
CDO in myogenesis Regulation of beta-cell development
Transcriptional regulation of white adipocyte differentiation LGI-ADAM interactions
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