Gene Symbol | HSPA4 |
Entrez Gene ID | 474680 |
Full Name | heat shock protein family A (Hsp70) member 4 |
Synonyms | APG-2 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
ORF » Species Summary » Canis lupus familiaris » HSPA4 cDNA ORF clone
Gene Symbol | HSPA4 |
Entrez Gene ID | 474680 |
Full Name | heat shock protein family A (Hsp70) member 4 |
Synonyms | APG-2 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(Dog) |
mRNA | Protein | Name |
---|---|---|
NM_001048016.1 | NP_001041481.1 | heat shock 70 kDa protein 4 |
XM_022424911.1 | XP_022280619.1 | heat shock 70 kDa protein 4 isoform X1 |
XM_005626399.2 | XP_005626456.1 | heat shock 70 kDa protein 4 isoform X2 |
XM_005626399.1 | XP_005626456.1 | heat shock 70 kDa protein 4 isoform X1 |
Gallus gallus (chicken) | HSPA4 | XP_414655.2 |
Caenorhabditis elegans (roundworm) | C30C11.4 | NP_498868.1 |
Saccharomyces cerevisiae (baker's yeast) | SSE1 | NP_015219.1 |
Eremothecium gossypii | AGOS_AGR212W | NP_986878.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06065 | XP_003711919.1 |
Arabidopsis thaliana (thale cress) | AT1G79920 | NP_850984.4 |
Oryza sativa (rice) | Os05g0181000 | NP_001054812.1 |
Homo sapiens (human) | HSPA4 | NP_002145.3 |
Mus musculus (house mouse) | Hspa4 | NP_032326.3 |
Danio rerio (zebrafish) | hspa4a | NP_999881.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010331 | XP_315285.3 |
Kluyveromyces lactis | KLLA0E24597g | XP_455059.1 |
Rattus norvegicus (Norway rat) | Hspa4 | NP_705893.1 |
HSPA4 | XP_001106968.1 | |
Danio rerio (zebrafish) | hspa4b | NP_956151.1 |
Drosophila melanogaster (fruit fly) | Hsc70Cb | NP_001189103.1 |
Schizosaccharomyces pombe (fission yeast) | pss1 | XP_001713060.1 |
Xenopus tropicalis (tropical clawed frog) | hspa4 | NP_989252.1 |
Pan troglodytes (chimpanzee) | HSPA4 | XP_517930.2 |
Canis lupus familiaris (dog) | HSPA4 | NP_001041481.1 |
Bos taurus (cattle) | HSPA4 | NP_001107664.1 |
Neurospora crassa | NCU05269 | XP_961759.2 |
Arabidopsis thaliana (thale cress) | HSP91 | NP_178111.1 |
Oryza sativa (rice) | Os01g0180800 | NP_001042210.1 |
Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2.
Aijaz S, Sanchez-Heras E, Balda MS, Matter K
BMC cell biology849(2007 Nov)
The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.
Tsapara A, Matter K, Balda MS
Molecular biology of the cell17(3)1322-30(2006 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Silencing of apg-2 in MDCK cells did not prevent but retarded de novo junction assembly and in 3D matrix gels lead to formation of but poorly organised, irregular structures insted of hollow polarised cysts
Title: Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2.
Apg-2 regulates ZONAB function by competing for binding to the SH3 domain of ZO-1 and suggest that Apg-2 functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress.
Title: The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.
The following HSPA4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSPA4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00214 | |
Clone ID Related Accession (Same CDS sequence) | NM_001048016.1 | |
Accession Version | NM_001048016.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2523bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Canis lupus familiaris(dog) | |
Product | heat shock 70 kDa protein 4 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY911512.1. On or before Sep 14, 2006 this sequence version replaced XM_531906.2, XM_856263.1, XM_856290.1, XM_856313.1, XM_856331.1, XM_856360.1, XM_856388.1, XM_856424.1, XM_856449.1, XM_856478.1, XM_856510.1, XM_856539.1, XM_856565.1, XM_856598.1, XM_856630.1. ##Evidence-Data-START## Transcript exon combination :: AY911512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCGGTCG TGGGGATAGA CCTGGGCTTC CAGAGCTGCT ACGTCGCCGT GGCCCGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041481.1 |
CDS | 226..2748 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001048016.1 |
1 | ATGTCGGTCG TGGGGATAGA CCTGGGCTTC CAGAGCTGCT ACGTCGCCGT GGCCCGCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe14137 | |
Clone ID Related Accession (Same CDS sequence) | XM_005626399.2 , XM_005626399.1 | |
Accession Version | XM_005626399.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2565bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | heat shock 70 kDa protein 4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006593.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005626399.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCATGGGA GTCGCCATCT TAGCGCGGCT GAGCACTGCC GCGCGGGGTT TTGGGAAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005626456.1 |
CDS | 19..2583 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005626399.2 |
1 | ATGCATGGGA GTCGCCATCT TAGCGCGGCT GAGCACTGCC GCGCGGGGTT TTGGGAAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe14137 | |
Clone ID Related Accession (Same CDS sequence) | XM_005626399.2 , XM_005626399.1 | |
Accession Version | XM_005626399.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2565bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-09-16 | |
Organism | Canis lupus familiaris(Dog) | |
Product | heat shock 70 kDa protein 4 isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726080.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCATGGGA GTCGCCATCT TAGCGCGGCT GAGCACTGCC GCGCGGGGTT TTGGGAAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005626456.1 |
CDS | 18..2582 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005626399.1 |
1 | ATGCATGGGA GTCGCCATCT TAGCGCGGCT GAGCACTGCC GCGCGGGGTT TTGGGAAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe291747 | |
Clone ID Related Accession (Same CDS sequence) | XM_022424911.1 | |
Accession Version | XM_022424911.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2643bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-04 | |
Organism | Canis lupus familiaris(dog) | |
Product | heat shock 70 kDa protein 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006593.3) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCATGGGA GTCGCCATCT TAGCGCGGCT GAGCACTGCC GCGCGGGGTT TTGGGAAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_022280619.1 |
CDS | 19..2661 |
Translation |
Target ORF information:
Target ORF information:
|
XM_022424911.1 |
1 | ATGCATGGGA GTCGCCATCT TAGCGCGGCT GAGCACTGCC GCGCGGGGTT TTGGGAAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2. |
The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB. |