Gene Symbol | CDH1 |
Entrez Gene ID | 442858 |
Full Name | cadherin 1 |
Synonyms | Cadherin-1,Uvomorulin |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » CDH1 cDNA ORF clone
Gene Symbol | CDH1 |
Entrez Gene ID | 442858 |
Full Name | cadherin 1 |
Synonyms | Cadherin-1,Uvomorulin |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001287125.1 | NP_001274054.1 | cadherin-1 precursor |
CDH1 | XP_002802562.1 | |
Rattus norvegicus (Norway rat) | Cdh1 | NP_112624.1 |
Danio rerio (zebrafish) | cdh1 | NP_571895.1 |
Homo sapiens (human) | CDH1 | NP_004351.1 |
Danio rerio (zebrafish) | LOC568392 | XP_696808.4 |
Canis lupus familiaris (dog) | CDH1 | XP_536807.3 |
Xenopus tropicalis (tropical clawed frog) | LOC100485633 | XP_002936044.1 |
Bos taurus (cattle) | CDH1 | NP_001002763.1 |
Gallus gallus (chicken) | CDH1 | NP_001034347.2 |
Danio rerio (zebrafish) | si:dkey-173l11.3 | XP_005166659.1 |
Pan troglodytes (chimpanzee) | CDH1 | XP_001168150.1 |
Mus musculus (house mouse) | Cdh1 | NP_033994.1 |
Danio rerio (zebrafish) | si:ch211-206i14.2 | XP_695998.5 |
Danio rerio (zebrafish) | si:busm1-71b9.3 | XP_005166660.1 |
Src- and confinement-dependent FAK activation causes E-cadherin relaxation and ?-catenin activity.
Gayrard C, Bernaudin C, D?jardin T, Seiler C, Borghi N
The Journal of cell biology(2018 Jan)
Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma.
Siret C, Dobric A, Martirosyan A, Terciolo C, Germain S, Bonier R, Dirami T, Dusetti N, Tomasini R, Rubis M, Garcia S, Iovanna J, Lombardo D, Rigot V, Andr? F
British journal of cancer(2017 Nov)
E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape.
Hart KC, Tan J, Siemers KA, Sim JY, Pruitt BL, Nelson WJ, Gloerich M
Proceedings of the National Academy of Sciences of the United States of America114(29)E5845-E5853(2017 Jul)
Immunolocalization of E-cadherin and ?-catenin in the cyclic and early pregnant canine endometrium.
Payan-Carreira R, Pires MA, Santos C, Holst BS, Cola?o J, Rodriguez-Martinez H
Theriogenology86(4)1092-1101(2016 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The results show the existence of a softening of the adherens junctional complex in progestagen-dominated stages favoring embryo-maternal interactions and endometrial invasion during canine implantation.
Title: Immunolocalization of E-cadherin and ?-catenin in the cyclic and early pregnant canine endometrium.
All the hyperplastic samples stained positive for both markers, 100% of adenomas were positive for PTEN and 86% for E-cadherin, and 69% and 34% of carcinomas were positive for PTEN and E-cadherin, respectively.
Title: Co-localization of PTEN and E-cadherin in canine mammary hyperplasias and benign and malignant mammary tumors.
ZEB1 appears to not exert E-cadherin transcriptional repression activity
Title: The Relationship Between E-Cadherin and its Transcriptional Repressors in Spontaneously Arising Canine Invasive Micropapillary Mammary Carcinoma.
the allosteric regulation of cell surface E-cadherin by p120(ctn) dephosphorylation.
Title: Allosteric Regulation of E-Cadherin Adhesion.
Epithelial cells with disrupted E-cadherin gene retain the ability to form cell junctions and apico-basal polarity.
Title: Epithelial DLD-1 Cells with Disrupted E-cadherin Gene Retain the Ability to Form Cell Junctions and Apico-basal Polarity.
The following CDH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe00006 | |
Clone ID Related Accession (Same CDS sequence) | NM_001287125.1 | |
Accession Version | NM_001287125.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2658bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Canis lupus familiaris(dog) | |
Product | cadherin-1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03004114.1. On Nov 27, 2013 this sequence version replaced XM_536807.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN07419784 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCCCTC GGTACGGCGG CGCCCCCGCG CTCCTGCTCC CGCTGCTGCT GCTGCTGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001274054.1 |
CDS | 48..2705 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001287125.1 |
1 | ATGGGCCCTC GGTACGGCGG CGCCCCCGCG CTCCTGCTCC CGCTGCTGCT GCTGCTGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Src- and confinement-dependent FAK activation causes E-cadherin relaxation and ?-catenin activity. |
Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma. |
E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape. |
Immunolocalization of E-cadherin and ?-catenin in the cyclic and early pregnant canine endometrium. |