Gene Symbol | CYP3A26 |
Entrez Gene ID | 415127 |
Full Name | cytochrome P450 3A26 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » CYP3A26 cDNA ORF clone
Gene Symbol | CYP3A26 |
Entrez Gene ID | 415127 |
Full Name | cytochrome P450 3A26 |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001003338.1 | NP_001003338.1 | cytochrome P450 3A26 |
Canis lupus familiaris (dog) | CYP3A26 | NP_001003338.1 |
Canis lupus familiaris (dog) | LOC489851 | XP_546969.2 |
Gallus gallus (chicken) | CYP3A4 | XP_414782.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012296 | XP_551896.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012292 | XP_001238280.1 |
Caenorhabditis elegans (roundworm) | cyp-25A2 | NP_497776.2 |
Bos taurus (cattle) | CYP3A5 | NP_001069356.1 |
Drosophila melanogaster (fruit fly) | Cyp9f2 | NP_650189.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100487846 | XP_002937898.2 |
Homo sapiens (human) | CYP3A4 | NP_059488.2 |
CYP3A4 | NP_001035504.1 | |
Canis lupus familiaris (dog) | CYP3A4 | XP_536868.2 |
Anopheles gambiae (African malaria mosquito) | CYP9L1 | XP_320243.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000818 | XP_316781.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012850 | XP_561320.5 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012293 | XP_001689238.1 |
Caenorhabditis elegans (roundworm) | cyp-25A3 | NP_001040850.1 |
Caenorhabditis elegans (roundworm) | cyp-25A4 | NP_497779.1 |
Caenorhabditis elegans (roundworm) | cyp-25A6 | NP_500512.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100487054 | XP_002937893.2 |
Canis lupus familiaris (dog) | CYP3A12 | NP_001003340.1 |
Caenorhabditis elegans (roundworm) | cyp-25A1 | NP_497775.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_04911 | XP_003712400.1 |
Pan troglodytes (chimpanzee) | CYP3A4 | NP_001116247.1 |
Bos taurus (cattle) | CYP3A4 | NP_001092837.1 |
Rattus norvegicus (Norway rat) | Cyp3a2 | NP_695224.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012294 | XP_001238278.2 |
Caenorhabditis elegans (roundworm) | cyp-25A5 | NP_500322.1 |
Differential expression of CYP3A12 and CYP3A26 mRNAs in canine liver and intestine.
Mealey KL, Jabbes M, Spencer E, Akey JM
Xenobiotica; the fate of foreign compounds in biological systems38(10)1305-12(2008 Oct)
Importance of amino acid residue 474 for substrate specificity of canine and human cytochrome p450 3A enzymes.
He YQ, Roussel F, Halpert JR
Archives of biochemistry and biophysics389(2)264-70(2001 May)
Use of chimeric enzymes and site-directed mutagenesis for identification of three key residues responsible for differences in steroid hydroxylation between canine cytochromes P-450 3A12 and 3A26.
Fraser DJ, He YQ, Harlow GR, Halpert JR
Molecular pharmacology55(2)241-7(1999 Feb)
Isolation, heterologous expression and functional characterization of a novel cytochrome P450 3A enzyme from a canine liver cDNA library.
Fraser DJ, Feyereisen R, Harlow GR, Halpert JR
The Journal of pharmacology and experimental therapeutics283(3)1425-32(1997 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
In summary, these results represent an important step toward the systematic comparison of human and canine CYP3A enzymes, particularly in relation to oral bioavailability of substrate drugs.
Title: Differential expression of CYP3A12 and CYP3A26 mRNAs in canine liver and intestine.
The following CYP3A26 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP3A26 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe34104 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003338.1 | |
Accession Version | NM_001003338.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-21 | |
Organism | Canis lupus familiaris(dog) | |
Product | cytochrome P450 3A26 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF547269.1. ##Evidence-Data-START## Transcript exon combination :: AF547269.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547745, SAMN00013515 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACTTGA TCCCAAGCTT TTCCACAGAA ACCTGGCTTC TTCTGGCTAT CAGCCTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003338.1 |
CDS | 82..1593 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003338.1 |
1 | ATGGACTTGA TCCCAAGCTT TTCCACAGAA ACCTGGCTTC TTCTGGCTAT CAGCCTGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Differential expression of CYP3A12 and CYP3A26 mRNAs in canine liver and intestine. |
Importance of amino acid residue 474 for substrate specificity of canine and human cytochrome p450 3A enzymes. |
Use of chimeric enzymes and site-directed mutagenesis for identification of three key residues responsible for differences in steroid hydroxylation between canine cytochromes P-450 3A12 and 3A26. |
Isolation, heterologous expression and functional characterization of a novel cytochrome P450 3A enzyme from a canine liver cDNA library. |