FGF3 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	FGF3
Entrez Gene ID	396267
Full Name	fibroblast growth factor 3
Synonyms	INT-2
General protein information	Preferred Names fibroblast growth factor 3 Names fibroblast growth factor 3 FGF-3 HBGF-3 Int-2 proto-oncogene protein fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) heparin-binding growth factor 3
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205327.1	NP_990658.1	fibroblast growth factor 3 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	FGF3	NP_005238.1
	FGF3	XP_001100658.1
Rattus norvegicus (Norway rat)	Fgf3	NP_570830.1
Xenopus tropicalis (tropical clawed frog)	fgf3	NP_001008154.1
Bos taurus (cattle)	FGF3	XP_002699485.1
Mus musculus (house mouse)	Fgf3	NP_032033.2
Pan troglodytes (chimpanzee)	FGF3	XP_522092.2
Gallus gallus (chicken)	FGF3	NP_990658.1
Danio rerio (zebrafish)	fgf3	NP_571366.1

Gene Ontology
Bibliography

Related articles in PubMed

Fgf3 and Fgf16 expression patterns define spatial and temporal domains in the developing chick inner ear.
Olaya-S?nchez D, S?nchez-Guardado L?, Ohta S, Chapman SC, Schoenwolf GC, Puelles L, Hidalgo-S?nchez M
Brain structure & function222(1)131-149(2017 01)

Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis.
Liu F, Pogoda HM, Pearson CA, Ohyama K, L?hr H, Hammerschmidt M, Placzek M
Development (Cambridge, England)140(5)1111-22(2013 Mar)

FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway.
Aragon F, Pujades C
BMC developmental biology961(2009 Dec)

Boundary cells regulate a switch in the expression of FGF3 in hindbrain rhombomeres.
Sela-Donenfeld D, Kayam G, Wilkinson DG
BMC developmental biology916(2009 Feb)

Int-2 influences the development of the nodose ganglion.
Qin F, Kirby ML
Pediatric research38(4)485-92(1995 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FGF3 and FGF16 seem to be key signaling pathways that control the inner ear plan by defining epithelial identities within the developing otic epithelium.
Title: Fgf3 and Fgf16 expression patterns define spatial and temporal domains in the developing chick inner ear.

Fgf10 and Fgf3 secreted from the forming neurohypophysis exert direct guidance effects on hypothalamic neurosecretory axons.
Title: Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis.

Study shows that in the chick hindbrain, Fgf3 is transcriptionally activated as early as 30 min after mvHnf1 electroporation, suggesting that it is a direct target of this transcription factor.
Title: FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway.

These findings suggest that hindbrain boundary cells are required for the downregulation of segmental FGF3, presumably mediated by a soluble factor(s) that emanates from boundaries.
Title: Boundary cells regulate a switch in the expression of FGF3 in hindbrain rhombomeres.

The following FGF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27086	NM_205327.1 Latest version!	Gallus gallus fibroblast growth factor 3 (FGF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FGF3 ( NM_205327.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990658.1 Gallus gallus fibroblast growth factor 3 (FGF3), mRNA.

Price & Availability↑

CloneID	OGa27086
Clone ID Related Accession (Same CDS sequence)	NM_205327.1
Accession Version	NM_205327.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Gallus gallus(chicken)
Product	fibroblast growth factor 3 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z47555.1. ##Evidence-Data-START## Transcript exon combination :: Z47555.1, BU262770.1 [ECO:0000332] ##Evidence-Data-END##

ATGCTCGTGA TCTGGCTCCT GCTGCTCGCC CTGCTGCCCG AGCCGCGCGT CCCGGCCGCT 
ACGGCCTCCC CGAGGGCCCC GCGGGATGCG GGGGGGCGCG GCGGCGTCTA CGAGCACCTC 
GGGGGAGCGC CCCGCCGCAG GAAGCTCTAC TGTGCCACCA AGTACCACCT GCAGATCCAC 
CCCGGCGGCA AGATCAACGG CACCTTGGAG AAAAACAGCG TCTTCAGTAT CCTTGAAATA 
ACTGCTGTTG ATGTCGGGAT CGTCGCTATC AAGGGCTTGT TCTCTGGCAG ATACCTGGCC 
ATGAACAAAA GGGGCAGGCT TTATGCATCA GAGAACTATA ACACAGAATG TGAGTTTGTG 
GAGAGGATTC ATGAACTGGG CTACAACACC TATGCATCCC GTCTGTACCG AACTGTACCC 
AGTGGAGCCA GCACCAAGCG CAAAGCCAGT GCGGAGAGAC TCTGGTACGT CTCAGTCAAT 
GGGAAAGGAC GACCCAGGAG GGGCTTTAAA ACACGCAGGA CACAGAAATC CTCCCTCTTT 
CTGCCCAGAG TATTGGATAG CAAAGACCAT GAAATGGTCC GACTTTTCCA CACAAATGTG 
AGATACCGAG AGAGCCTCCT GAAGCCTCCC AGTAAGAACC AGAGGAGAAG GAGAGGACGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990658.1
CDS	1..663
Translation	MLVIWLLLLALLPEPRVPAATASPRAPRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQIHPGGKINGTLEKNSVFSILEITAVDVGIVAIKGLFSGRYLAMNKRGRLYASENYNTECEFVERIHELGYNTYASRLYRTVPSGASTKRKASAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDSKDHEMVRLFHTNVRYRESLLKPPSKNQRRRRGR

Target ORF information:

RefSeq Version	NM_205327.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus fibroblast growth factor 3 (FGF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205327.1

ORF Insert Sequence:

ATGCTCGTGA TCTGGCTCCT GCTGCTCGCC CTGCTGCCCG AGCCGCGCGT CCCGGCCGCT 
ACGGCCTCCC CGAGGGCCCC GCGGGATGCG GGGGGGCGCG GCGGCGTCTA CGAGCACCTC 
GGGGGAGCGC CCCGCCGCAG GAAGCTCTAC TGTGCCACCA AGTACCACCT GCAGATCCAC 
CCCGGCGGCA AGATCAACGG CACCTTGGAG AAAAACAGCG TCTTCAGTAT CCTTGAAATA 
ACTGCTGTTG ATGTCGGGAT CGTCGCTATC AAGGGCTTGT TCTCTGGCAG ATACCTGGCC 
ATGAACAAAA GGGGCAGGCT TTATGCATCA GAGAACTATA ACACAGAATG TGAGTTTGTG 
GAGAGGATTC ATGAACTGGG CTACAACACC TATGCATCCC GTCTGTACCG AACTGTACCC 
AGTGGAGCCA GCACCAAGCG CAAAGCCAGT GCGGAGAGAC TCTGGTACGT CTCAGTCAAT 
GGGAAAGGAC GACCCAGGAG GGGCTTTAAA ACACGCAGGA CACAGAAATC CTCCCTCTTT 
CTGCCCAGAG TATTGGATAG CAAAGACCAT GAAATGGTCC GACTTTTCCA CACAAATGTG 
AGATACCGAG AGAGCCTCCT GAAGCCTCCC AGTAAGAACC AGAGGAGAAG GAGAGGACGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Fgf3 and Fgf16 expression patterns define spatial and temporal domains in the developing chick inner ear.
Brain structure & function222(1)131-149(2017 01)
Olaya-S?nchez D,S?nchez-Guardado L?,Ohta S,Chapman SC,Schoenwolf GC,Puelles L,Hidalgo-S?nchez M

Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis.
Development (Cambridge, England)140(5)1111-22(2013 Mar)
Liu F,Pogoda HM,Pearson CA,Ohyama K,L?hr H,Hammerschmidt M,Placzek M

FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway.
BMC developmental biology961(2009 Dec)
Aragon F,Pujades C

Boundary cells regulate a switch in the expression of FGF3 in hindbrain rhombomeres.
BMC developmental biology916(2009 Feb)
Sela-Donenfeld D,Kayam G,Wilkinson DG

Int-2 influences the development of the nodose ganglion.
Pediatric research38(4)485-92(1995 Oct)
Qin F,Kirby ML

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FGF3 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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