IGF1R cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	IGF1R
Entrez Gene ID	395889
Full Name	insulin like growth factor 1 receptor
Synonyms	IGF-1R
General protein information	Preferred Names insulin like growth factor 1 receptor Names insulin-like growth factor 1 receptor IGF-I receptor insulin-like growth factor I receptor insulin-like growth factor receptor tyrosine kinase type 1 IGF receptor tyrosine kinase
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205032.1	NP_990363.1	insulin-like growth factor 1 receptor precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	IGF1R	XP_510613.2
Canis lupus familiaris (dog)	IGF1R	XP_545828.2
Mus musculus (house mouse)	Igf1r	NP_034643.2
Gallus gallus (chicken)	IGF1R	NP_990363.1
Bos taurus (cattle)	IGF1R	NP_001231541.1
Danio rerio (zebrafish)	igf1ra	NP_694500.1
Caenorhabditis elegans (roundworm)	daf-2	NP_497650.4
Homo sapiens (human)	IGF1R	NP_000866.1
Rattus norvegicus (Norway rat)	Igf1r	NP_434694.1
Danio rerio (zebrafish)	igf1rb	NP_694501.1
Anopheles gambiae (African malaria mosquito)	INR	XP_320130.3
Xenopus tropicalis (tropical clawed frog)	igf1r	XP_002933351.1
	IGF1R	XP_001100407.1
Drosophila melanogaster (fruit fly)	InR	NP_001138093.1

Gene Ontology
Bibliography

Related articles in PubMed

Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens.
Jin S, Chen S, Li H, Lu Y, Xu G, Yang N
Molecular biology reports41(6)3973-9(2014 Jun)

?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation.
Basu S, Rajakaruna S, De Arcangelis A, Zhang L, Georges-Labouesse E, Menko AS
The Journal of biological chemistry289(7)3842-55(2014 Feb)

Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.
Basu S, Rajakaruna S, Menko AS
The Journal of biological chemistry287(11)8384-97(2012 Mar)

Insulin, insulin-like growth factor-1, insulin receptor, and insulin-like growth factor-1 receptor expression in the chick eye and their regulation with imposed myopic or hyperopic defocus.
Penha AM, Schaeffel F, Feldkaemper M
Molecular vision171436-48(2011)

Polymorphisms of the IGF1R gene and their genetic effects on chicken early growth and carcass traits.
Lei M, Peng X, Zhou M, Luo C, Nie Q, Zhang X
BMC genetics970(2008 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Rs14011780 of IGF1R was strongly associated with body weight (BW), body weight gain and FCR (P < 0.05)
Title: Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens.

alpha6 integrin is an essential upstream regulator of the IGF-1R survival pathway that regulates the activity level of caspase-3 for it to signal differentiation initiation of lens epithelial cells.
Title: ?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation.

the IGF-1R/NFkappaB cell survival signal is a crucial regulator of the level of caspase-3 activation for its non-apoptotic function in signaling cell differentiation.
Title: Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.

The differential regulation of insulin receptor and insulin-like growth factor-1 receptor in the the retinal pigment epithelium (RPE), choroid, and fibrous sclera is consistent with their involvement in a signaling cascade for emmetropization.
Title: Insulin, insulin-like growth factor-1, insulin receptor, and insulin-like growth factor-1 receptor expression in the chick eye and their regulation with imposed myopic or hyperopic defocus.

6 SNPs in the IGF1R gene are associated with chicken early growth and carcass traits.
Title: Polymorphisms of the IGF1R gene and their genetic effects on chicken early growth and carcass traits.

The following IGF1R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IGF1R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00381	NM_205032.1 Latest version!	Gallus gallus insulin like growth factor 1 receptor (IGF1R), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$797.30 $1139.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IGF1R ( NM_205032.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990363.1 Gallus gallus insulin like growth factor 1 receptor (IGF1R), mRNA.

Price & Availability↑

CloneID	OGa00381
Clone ID Related Accession (Same CDS sequence)	NM_205032.1
Accession Version	NM_205032.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-11-05
Organism	Gallus gallus(chicken)
Product	insulin-like growth factor 1 receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ223164.1. ##Evidence-Data-START## Transcript exon combination :: AJ223164.1 [ECO:0000332] ##Evidence-Data-END##

ATGAAGTCTG GCGCTGGAGG AGGGACCCTC GCCGTCTTCT GCGGGTTGCT GCTCGCCTTC 
GCCGCGCTCT GCCTGTGTCC GACAAATGGG GAAATTTGTG GGCCAAACGT TGACATTCGC 
AATGATATCC ATGAGCTGAA ACGCCTGGAG AACTGTACGG TCGTTGAGGG TTTCCTTCAG 
ATCCTGCTCA TCTCTAAAGC AGAGGATTAC CGCAACTTCC GCTTCCCGAA ACTGACCGTC 
ATAACTGACT ACTTGCTGCT GTTCCGTGTG GCGGGCTTGG AAAGCCTCAG CGATCTCTTC 
CCCAACCTCA CGGTCATTCG CGGGAGGAAC CTCTTCTACA ACTATGCCTT GGTGATCTTC 
GAAATGACAA ATCTGAAGGA GATCGGGCTT CACAACTTGA GGAACATAAC CCGCGGGGCC 
ATACGGATTG AGAAGAACTC TGACCTGTGT TACCTCTCCA CAGTGGACTG GTCTCTCATC 
CTAGATGCGG TCTCTAATAA CTACATTGTT GGAAATAAGC CTCCGAAGGA GTGCGGGGAC 
TTGTGTCCAG GAACGATGGA GGAGAAGCCG TTGTGCGAGA AGACCTCCAT TAACAACGAG 
TACAACTACC GCTGCTGGAC CACCAACCAC TGCCAGAAAA TGTGCCCCAG CTCATGTGGC 
AAGAGAGCCT GCACAGACCA GAATGAGTGT TGCCATCCTG AGTGCCTGGG GAGCTGCACA 
GCACCCGACA ACAACACTGC TTGCGTGGCC TGCCGCAATT ACTACTACGA AGGCGTCTGC 
ATGCCCACCT GCCCTCCCAA CACGTACAAG TTTGAGGGCT GGCGCTGTGT GACCAAGGAG 
TTCTGCTCCA AAGTCCCTGC CACTGAAACA AGTGACTACG AGAGGTTTGT GATTCACAAC 
GATGAGTGCA TGGCAGAGTG CCCCTCTGGA TTCATACGCA ATGGGAGCCA AAGTATGTTC 
TGCAGTCCTT GTGAGGGGCC TTGCCCCAAA ATTTGTGAGG ATGGGAAAAC GAAGACCATY 
GACTCTGTCA CGTCAGCACA AATGTTGCAG GGATGCACAA TTCTCAAGGG AAATTTGCTG 
ATCAACATCC GTCGTGGAAA TAACATCGCT TCAGAACTGG AGAATTTCAT GGGTCTGATT 
GAGACAGTGA CGGGATATGT GAAGATTCGC CATTCCCATG CATTAGTTTC CCTGTCTTTC 
TTGAAGAACC TGCGGTATAT TCTGGGAGAG GAGCAGGTGG ATGGGAATTA TTCTTTTTAT 
GTGCTTGATA ACCACAATCT GCAGCAACTG TGGGACTGGA ACCATCATAA CTTGACGATC 
AAGGAGGGGA AAATGTACTT TGCATTTAAT CCTAAACTGT GTGTTTCTGA GATCTACCGT 
ATGGAGGAAG TTTCAGGAAC CAAAGGGCGA CAGAGCAAAG GAGATATAAA TCCAAGGAAC 
AATGGGGAGA GAGCCTCTTG TGAAAGCCAC ATTCTGCGTT TTGTTTCCAA CACAACACTG 
AAGAATCGGA TTAAACTGAC GTGGGAGCGG TATCGCCCTC CAGATTACAG AGATCTCATT 
AGCTTCACTG TTTACTACAA AGAAGCGCCG TTCAAAAATG TGACAGAGTA TGATGGACAA 
GATGCGTGCG GCTCCAATAG CTGGAATATG GTTGATGTTG ACTTGCCACC AAACAAGGAG 
AATGACCCTG GAATCTTACT GCAGGGATTG AAACCTTGGA CTCAGTATGC CATTTATGTC 
AAGGCTGTTA CCCTCACAAT GATGGAGAAC CATCACATTC ATGGAGCAAA AAGTGAAATT 
GTGTATATAC GAACCAATGC TGCAGTACCA TCCATTCCCT TAGATGTTAT TTCAGCATCC 
AACTCCTCTT CCCAATTGAT TGTGAAATGG AATCCTCCCT CTCTTCCCAA TGGCAACCTC 
TCATACTATA TTGTACGATG GCAGCAGCAA CCTCAGGACA GTTACCTTTA CAGACACAAT 
TACTGCTCCA AAGATAAAGT CCCAATTCGA AGATATGCTG ATGGTACCAT TGATACAGAA 
GAAGCTACTG AACCCACCAA GCCAGAGGGC TGTGGGGGAG AAAAAGGACC TTGTTGTGCT 
TGTCCCAAGA CAGAGGCAGA AAAACAAGCT GAGAAGGAGG AAGCGGAGTA CCGGAAAGTC 
TTTGAGAACT TCCTTCACAA CTCCATCTTT GTCCCCAGAC CTGATCGGAA GCGGAGGGAT 
GTGTTCCGAA TTGCAAATGC CACTTTGGCC ACTCGAAACA GGAACATAAC TGGGGCAGAT 
CACTTCACCA ATGCTTCTGA CGCAGAGGAG AGTGAGGTGG AATACCCGTT CTTTGAGACC 
AAAGTGGATG GCAAGGAGAG AACTGTGATC TCCCATCTCC AGCCTTTTAC TCTTTACCGC 
ATTGATATTC ACAGCTGCAA CCATGAAGCT GACACGCTTG GTTGCAGCGC TTCCAACTTT 
GTCTTTGCAA GAACCATGCC TTCAGAGGGA GCAGATAACA TTCCAGGAAC AGTAGCATGG 
GAAGCAAAAG AAGAAAATAC TGTCTACCTG AAGTGGTTAG AGCCTACAAA TCCAAATGGG 
CTGATACTGA TGTATGAAAT CAAGTATGGG CAGCATGGGG AGGAGAAACG AGAATGTGTT 
TCGAGACAGG AGTACAAGAA GCTTGGAGGG GCAAAGCTGA CACATCTGAA CCCCGGAAAC 
TATTCTGCTA GAGTTCAGGC CACGTCATTG GCTGGAAATG GATCTTGGAC TGAGCCAGTC 
TCTTTCTATG TACAACCCAA ATCAGCAAAC TATGACAACT TCCTCCATTT GATAATTGTG 
CTCCCCATTG CTTTCCTGCT CATCATTGGG GGTTTGCTGA TAATGCTGTA TGTCTTTAAC 
AAGAAGAGGA ACAGTGACAG ACTGGGCAAT GGAGTACTTT ATGCATCTGT GAACCCTGAG 
TACTTCAGTG CTTCGGATGT GTACGTTCCA GACGAATGGG AGGTGCCCCG CGAGAAGATC 
ACCATGTGCC GTGAGCTTGG GCAGGGCTCT TTTGGGATGG TGTATGAGGG AATAGCCAAG 
GGAGTGGTGA AGGATGAGCC GGAGACCCGG GTGGCCATCA AAACRGTCAA TGAGTCTGCA 
AGCATGCGTG AGAGGATAGA GTTCTTAAAT GAGGCCTCGG TGATGAAGGA GTTCAATTGT 
CACCACGTGG TTCGCCTGCT AGGTGTTGTT TCTCAGGGCC AGCCTACCCT AGTTATCATG 
GAGCTGATGA CACGTGGGGA CCTCAAAAGT TACCTGAGAT CATTGAGGCC AGACACAGAG 
AGTAATCCTG GCCAAGCACC TCCAACTCTG AAGAAGATGA TTCAAATGGC AGGAGAGATT 
GCTGATGGGA TGGCATACCT CAACGCCAAC AAATTTGTTC ACAGAGATCT TGCTGCGAGG 
AACTGCATGG TGGCAGAAGA TTTCACGGTG AAAATCGGAG ATTTTGGCAT GACAAGAGAT 
ATCTACGAGA CAGATTATTA CCGGAAAGGA GGGAAAGGTT TGCTGCCCGT CCGCTGGATG 
TCCCCGGAAT CACTGAAGGA TGGAGTCTTC ACAACACACT CCGATGTCTG GTCTTTTGGT 
GTTGTACTTT GGGAGATCGC AACATTAGCA GAGCAGCCGT ACCAAGGCAT GACCAATGAG 
CAAGTGCTCC GCTTTGTGAT GGAAGGAGGT CTGCTGGAAA AACCAGACAA TTGCCCTGAT 
ATGCTGTTTG AACTGATGCG CATGTGCTGG CAGTACAACC CGAAGATGAG GCCGTCCTTC 
CTGGAAATCA TCAGCAGCAT TAAGGACGAG CTGGATCCGG CGTTCAAAGA GGTCTCCTTC 
TTCTACAGCG AAGAGAACAA GCCTCCGGAC ACAGAGGAGC TTGACCTGGA GACTGAGAAC 
ATGGAGAGCA TTCCTTTAGA TCCCTCCTCT ACCCTCCAAC CCACTGACAA GCACTCAGGA 
CACAAAGCCG AGAACGGCCC GGGCGTGGTG GTCCTTCGGG CCAGCTTCGA GGAGAGACAG 
CCGTACGCAC ACATGAACGG GGGACGCAAG AACGAGAGGG CCTTACCGCT GCCCCAGTCT 
TCGGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990363.1
CDS	146..4237
Translation	MKSGAGGGTLAVFCGLLLAFAALCLCPTNGEICGPNVDIRNDIHELKRLENCTVVEGFLQILLISKAEDYRNFRFPKLTVITDYLLLFRVAGLESLSDLFPNLTVIRGRNLFYNYALVIFEMTNLKEIGLHNLRNITRGAIRIEKNSDLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPLCEKTSINNEYNYRCWTTNHCQKMCPSSCGKRACTDQNECCHPECLGSCTAPDNNTACVACRNYYYEGVCMPTCPPNTYKFEGWRCVTKEFCSKVPATETSDYERFVIHNDECMAECPSGFIRNGSQSMFCSPCEGPCPKICEDGKTKTnullDSVTSAQMLQGCTILKGNLLINIRRGNNIASELENFMGLIETVTGYVKIRHSHALVSLSFLKNLRYILGEEQVDGNYSFYVLDNHNLQQLWDWNHHNLTIKEGKMYFAFNPKLCVSEIYRMEEVSGTKGRQSKGDINPRNNGERASCESHILRFVSNTTLKNRIKLTWERYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKENDPGILLQGLKPWTQYAIYVKAVTLTMMENHHIHGAKSEIVYIRTNAAVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQDSYLYRHNYCSKDKVPIRRYADGTIDTEEATEPTKPEGCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPDRKRRDVFRIANATLATRNRNITGADHFTNASDAEESEVEYPFFETKVDGKERTVISHLQPFTLYRIDIHSCNHEADTLGCSASNFVFARTMPSEGADNIPGTVAWEAKEENTVYLKWLEPTNPNGLILMYEIKYGQHGEEKRECVSRQEYKKLGGAKLTHLNPGNYSARVQATSLAGNGSWTEPVSFYVQPKSANYDNFLHLIIVLPIAFLLIIGGLLIMLYVFNKKRNSDRLGNGVLYASVNPEYFSASDVYVPDEWEVPREKITMCRELGQGSFGMVYEGIAKGVVKDEPETRVAIKnullVNESASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPDTESNPGQAPPTLKKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATLAEQPYQGMTNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKDELDPAFKEVSFFYSEENKPPDTEELDLETENMESIPLDPSSTLQPTDKHSGHKAENGPGVVVLRASFEERQPYAHMNGGRKNERALPLPQSSAC

Target ORF information:

RefSeq Version	NM_205032.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus insulin like growth factor 1 receptor (IGF1R), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205032.1

ORF Insert Sequence:

ATGAAGTCTG GCGCTGGAGG AGGGACCCTC GCCGTCTTCT GCGGGTTGCT GCTCGCCTTC 
GCCGCGCTCT GCCTGTGTCC GACAAATGGG GAAATTTGTG GGCCAAACGT TGACATTCGC 
AATGATATCC ATGAGCTGAA ACGCCTGGAG AACTGTACGG TCGTTGAGGG TTTCCTTCAG 
ATCCTGCTCA TCTCTAAAGC AGAGGATTAC CGCAACTTCC GCTTCCCGAA ACTGACCGTC 
ATAACTGACT ACTTGCTGCT GTTCCGTGTG GCGGGCTTGG AAAGCCTCAG CGATCTCTTC 
CCCAACCTCA CGGTCATTCG CGGGAGGAAC CTCTTCTACA ACTATGCCTT GGTGATCTTC 
GAAATGACAA ATCTGAAGGA GATCGGGCTT CACAACTTGA GGAACATAAC CCGCGGGGCC 
ATACGGATTG AGAAGAACTC TGACCTGTGT TACCTCTCCA CAGTGGACTG GTCTCTCATC 
CTAGATGCGG TCTCTAATAA CTACATTGTT GGAAATAAGC CTCCGAAGGA GTGCGGGGAC 
TTGTGTCCAG GAACGATGGA GGAGAAGCCG TTGTGCGAGA AGACCTCCAT TAACAACGAG 
TACAACTACC GCTGCTGGAC CACCAACCAC TGCCAGAAAA TGTGCCCCAG CTCATGTGGC 
AAGAGAGCCT GCACAGACCA GAATGAGTGT TGCCATCCTG AGTGCCTGGG GAGCTGCACA 
GCACCCGACA ACAACACTGC TTGCGTGGCC TGCCGCAATT ACTACTACGA AGGCGTCTGC 
ATGCCCACCT GCCCTCCCAA CACGTACAAG TTTGAGGGCT GGCGCTGTGT GACCAAGGAG 
TTCTGCTCCA AAGTCCCTGC CACTGAAACA AGTGACTACG AGAGGTTTGT GATTCACAAC 
GATGAGTGCA TGGCAGAGTG CCCCTCTGGA TTCATACGCA ATGGGAGCCA AAGTATGTTC 
TGCAGTCCTT GTGAGGGGCC TTGCCCCAAA ATTTGTGAGG ATGGGAAAAC GAAGACCATY 
GACTCTGTCA CGTCAGCACA AATGTTGCAG GGATGCACAA TTCTCAAGGG AAATTTGCTG 
ATCAACATCC GTCGTGGAAA TAACATCGCT TCAGAACTGG AGAATTTCAT GGGTCTGATT 
GAGACAGTGA CGGGATATGT GAAGATTCGC CATTCCCATG CATTAGTTTC CCTGTCTTTC 
TTGAAGAACC TGCGGTATAT TCTGGGAGAG GAGCAGGTGG ATGGGAATTA TTCTTTTTAT 
GTGCTTGATA ACCACAATCT GCAGCAACTG TGGGACTGGA ACCATCATAA CTTGACGATC 
AAGGAGGGGA AAATGTACTT TGCATTTAAT CCTAAACTGT GTGTTTCTGA GATCTACCGT 
ATGGAGGAAG TTTCAGGAAC CAAAGGGCGA CAGAGCAAAG GAGATATAAA TCCAAGGAAC 
AATGGGGAGA GAGCCTCTTG TGAAAGCCAC ATTCTGCGTT TTGTTTCCAA CACAACACTG 
AAGAATCGGA TTAAACTGAC GTGGGAGCGG TATCGCCCTC CAGATTACAG AGATCTCATT 
AGCTTCACTG TTTACTACAA AGAAGCGCCG TTCAAAAATG TGACAGAGTA TGATGGACAA 
GATGCGTGCG GCTCCAATAG CTGGAATATG GTTGATGTTG ACTTGCCACC AAACAAGGAG 
AATGACCCTG GAATCTTACT GCAGGGATTG AAACCTTGGA CTCAGTATGC CATTTATGTC 
AAGGCTGTTA CCCTCACAAT GATGGAGAAC CATCACATTC ATGGAGCAAA AAGTGAAATT 
GTGTATATAC GAACCAATGC TGCAGTACCA TCCATTCCCT TAGATGTTAT TTCAGCATCC 
AACTCCTCTT CCCAATTGAT TGTGAAATGG AATCCTCCCT CTCTTCCCAA TGGCAACCTC 
TCATACTATA TTGTACGATG GCAGCAGCAA CCTCAGGACA GTTACCTTTA CAGACACAAT 
TACTGCTCCA AAGATAAAGT CCCAATTCGA AGATATGCTG ATGGTACCAT TGATACAGAA 
GAAGCTACTG AACCCACCAA GCCAGAGGGC TGTGGGGGAG AAAAAGGACC TTGTTGTGCT 
TGTCCCAAGA CAGAGGCAGA AAAACAAGCT GAGAAGGAGG AAGCGGAGTA CCGGAAAGTC 
TTTGAGAACT TCCTTCACAA CTCCATCTTT GTCCCCAGAC CTGATCGGAA GCGGAGGGAT 
GTGTTCCGAA TTGCAAATGC CACTTTGGCC ACTCGAAACA GGAACATAAC TGGGGCAGAT 
CACTTCACCA ATGCTTCTGA CGCAGAGGAG AGTGAGGTGG AATACCCGTT CTTTGAGACC 
AAAGTGGATG GCAAGGAGAG AACTGTGATC TCCCATCTCC AGCCTTTTAC TCTTTACCGC 
ATTGATATTC ACAGCTGCAA CCATGAAGCT GACACGCTTG GTTGCAGCGC TTCCAACTTT 
GTCTTTGCAA GAACCATGCC TTCAGAGGGA GCAGATAACA TTCCAGGAAC AGTAGCATGG 
GAAGCAAAAG AAGAAAATAC TGTCTACCTG AAGTGGTTAG AGCCTACAAA TCCAAATGGG 
CTGATACTGA TGTATGAAAT CAAGTATGGG CAGCATGGGG AGGAGAAACG AGAATGTGTT 
TCGAGACAGG AGTACAAGAA GCTTGGAGGG GCAAAGCTGA CACATCTGAA CCCCGGAAAC 
TATTCTGCTA GAGTTCAGGC CACGTCATTG GCTGGAAATG GATCTTGGAC TGAGCCAGTC 
TCTTTCTATG TACAACCCAA ATCAGCAAAC TATGACAACT TCCTCCATTT GATAATTGTG 
CTCCCCATTG CTTTCCTGCT CATCATTGGG GGTTTGCTGA TAATGCTGTA TGTCTTTAAC 
AAGAAGAGGA ACAGTGACAG ACTGGGCAAT GGAGTACTTT ATGCATCTGT GAACCCTGAG 
TACTTCAGTG CTTCGGATGT GTACGTTCCA GACGAATGGG AGGTGCCCCG CGAGAAGATC 
ACCATGTGCC GTGAGCTTGG GCAGGGCTCT TTTGGGATGG TGTATGAGGG AATAGCCAAG 
GGAGTGGTGA AGGATGAGCC GGAGACCCGG GTGGCCATCA AAACRGTCAA TGAGTCTGCA 
AGCATGCGTG AGAGGATAGA GTTCTTAAAT GAGGCCTCGG TGATGAAGGA GTTCAATTGT 
CACCACGTGG TTCGCCTGCT AGGTGTTGTT TCTCAGGGCC AGCCTACCCT AGTTATCATG 
GAGCTGATGA CACGTGGGGA CCTCAAAAGT TACCTGAGAT CATTGAGGCC AGACACAGAG 
AGTAATCCTG GCCAAGCACC TCCAACTCTG AAGAAGATGA TTCAAATGGC AGGAGAGATT 
GCTGATGGGA TGGCATACCT CAACGCCAAC AAATTTGTTC ACAGAGATCT TGCTGCGAGG 
AACTGCATGG TGGCAGAAGA TTTCACGGTG AAAATCGGAG ATTTTGGCAT GACAAGAGAT 
ATCTACGAGA CAGATTATTA CCGGAAAGGA GGGAAAGGTT TGCTGCCCGT CCGCTGGATG 
TCCCCGGAAT CACTGAAGGA TGGAGTCTTC ACAACACACT CCGATGTCTG GTCTTTTGGT 
GTTGTACTTT GGGAGATCGC AACATTAGCA GAGCAGCCGT ACCAAGGCAT GACCAATGAG 
CAAGTGCTCC GCTTTGTGAT GGAAGGAGGT CTGCTGGAAA AACCAGACAA TTGCCCTGAT 
ATGCTGTTTG AACTGATGCG CATGTGCTGG CAGTACAACC CGAAGATGAG GCCGTCCTTC 
CTGGAAATCA TCAGCAGCAT TAAGGACGAG CTGGATCCGG CGTTCAAAGA GGTCTCCTTC 
TTCTACAGCG AAGAGAACAA GCCTCCGGAC ACAGAGGAGC TTGACCTGGA GACTGAGAAC 
ATGGAGAGCA TTCCTTTAGA TCCCTCCTCT ACCCTCCAAC CCACTGACAA GCACTCAGGA 
CACAAAGCCG AGAACGGCCC GGGCGTGGTG GTCCTTCGGG CCAGCTTCGA GGAGAGACAG 
CCGTACGCAC ACATGAACGG GGGACGCAAG AACGAGAGGG CCTTACCGCT GCCCCAGTCT 
TCGGCCTGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens.
Molecular biology reports41(6)3973-9(2014 Jun)
Jin S,Chen S,Li H,Lu Y,Xu G,Yang N

?6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation.
The Journal of biological chemistry289(7)3842-55(2014 Feb)
Basu S,Rajakaruna S,De Arcangelis A,Zhang L,Georges-Labouesse E,Menko AS

Insulin-like growth factor receptor-1 and nuclear factor ?B are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.
The Journal of biological chemistry287(11)8384-97(2012 Mar)
Basu S,Rajakaruna S,Menko AS

Insulin, insulin-like growth factor-1, insulin receptor, and insulin-like growth factor-1 receptor expression in the chick eye and their regulation with imposed myopic or hyperopic defocus.
Molecular vision171436-48(2011)
Penha AM,Schaeffel F,Feldkaemper M

Polymorphisms of the IGF1R gene and their genetic effects on chicken early growth and carcass traits.
BMC genetics970(2008 Nov)
Lei M,Peng X,Zhou M,Luo C,Nie Q,Zhang X

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IGF1R cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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