Gene Symbol | nac-2 |
Entrez Gene ID | 187898 |
Full Name | NADC (Na+-coupled dicarboxylate transporter) family |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » nac-2 cDNA ORF clone
Gene Symbol | nac-2 |
Entrez Gene ID | 187898 |
Full Name | NADC (Na+-coupled dicarboxylate transporter) family |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001268048.1 | NP_001254977.1 | Sodium-dependent high-affinity dicarboxylate transporter 2 |
NM_001268048.2 | NP_001254977.1 | Sodium-dependent high-affinity dicarboxylate transporter 2 |
NM_001268047.2 | NP_001254976.1 | Sodium-dependent high-affinity dicarboxylate transporter 2 |
NM_001268047.1 | NP_001254976.1 | Sodium-dependent high-affinity dicarboxylate transporter 2 |
SLC13A3 | XP_002798175.1 | |
Caenorhabditis elegans (roundworm) | CELE_B0285.6 | NP_497877.1 |
Homo sapiens (human) | SLC13A3 | NP_073740.2 |
Canis lupus familiaris (dog) | SLC13A3 | XP_543034.2 |
Rattus norvegicus (Norway rat) | Slc13a3 | NP_074057.2 |
Danio rerio (zebrafish) | slc13a3 | NP_998067.1 |
Caenorhabditis elegans (roundworm) | nac-2 | NP_001254976.1 |
Xenopus tropicalis (tropical clawed frog) | slc13a3 | NP_001015776.1 |
Bos taurus (cattle) | SLC13A3 | NP_001073757.1 |
Pan troglodytes (chimpanzee) | SLC13A3 | XP_514696.2 |
Mus musculus (house mouse) | Slc13a3 | NP_473396.1 |
Gallus gallus (chicken) | SLC13A3 | XP_003642529.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Knockdown of Indy/CeNAC2 increased life span by 22+/-3 % compared to controls, together with a decrease in whole body fat content by ~50%. Indy/CeNAC2 reduction also increased the activation of the intracellular energy sensor AMPK/aak2.
Title: Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2.
ceNAC-2 mediates the Na+-coupled electrogenic transport of various intermediates of the citric acid cycle. Its loss leads to a significant increase in life span, but also causes a significant decrease in body size and fat content.
Title: Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans.
The following nac-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nac-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340067 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268048.1 , NM_001268048.2 | |
Accession Version | NM_001268048.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Sodium-dependent high-affinity dicarboxylate transporter 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGAAGCCTA GCCCCCAGCG TACGTTAATA AAAAAGCTTC TGGTACTTCT TGGACCACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001254977.1 |
CDS | 1..1656 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268048.1 |
1 | ATGAAGCCTA GCCCCCAGCG TACGTTAATA AAAAAGCTTC TGGTACTTCT TGGACCACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340067 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268048.1 , NM_001268048.2 | |
Accession Version | NM_001268048.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Sodium-dependent high-affinity dicarboxylate transporter 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001268048.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGAAGCCTA GCCCCCAGCG TACGTTAATA AAAAAGCTTC TGGTACTTCT TGGACCACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001254977.1 |
CDS | 1..1656 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268048.2 |
1 | ATGAAGCCTA GCCCCCAGCG TACGTTAATA AAAAAGCTTC TGGTACTTCT TGGACCACTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340523 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268047.2 , NM_001268047.1 | |
Accession Version | NM_001268047.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Sodium-dependent high-affinity dicarboxylate transporter 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001268047.1. |
1 | ATGAAACTAA ATTTTCTAGC AGCTTGTATG AAGAAACTTT TTCGATTTAA TTATGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001254976.1 |
CDS | 152..1909 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268047.2 |
1 | ATGAAACTAA ATTTTCTAGC AGCTTGTATG AAGAAACTTT TTCGATTTAA TTATGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340523 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268047.2 , NM_001268047.1 | |
Accession Version | NM_001268047.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Sodium-dependent high-affinity dicarboxylate transporter 2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGAAACTAA ATTTTCTAGC AGCTTGTATG AAGAAACTTT TTCGATTTAA TTATGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001254976.1 |
CDS | 1..1758 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268047.1 |
1 | ATGAAACTAA ATTTTCTAGC AGCTTGTATG AAGAAACTTT TTCGATTTAA TTATGGAACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |