Slc13a3 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc13a3
Entrez Gene ID	114644
Full Name	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
Synonyms	NaDC-3,NaDC3,SDCT2
General protein information	Preferred Names solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 Names solute carrier family 13 member 3 Na(+)/dicarboxylate cotransporter 3 mNaDC3 sodium-dependent high-affinity dicarboxylate transporter 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 2 Map Location: 2\|2 H3

mRNA and Protein(s)

mRNA	Protein	Name
NM_054055.2	NP_473396.1	solute carrier family 13 member 3

Pathways from BioSystems

Homologies

	SLC13A3	XP_002798175.1
Caenorhabditis elegans (roundworm)	CELE_B0285.6	NP_497877.1
Homo sapiens (human)	SLC13A3	NP_073740.2
Canis lupus familiaris (dog)	SLC13A3	XP_543034.2
Rattus norvegicus (Norway rat)	Slc13a3	NP_074057.2
Danio rerio (zebrafish)	slc13a3	NP_998067.1
Caenorhabditis elegans (roundworm)	nac-2	NP_001254976.1
Xenopus tropicalis (tropical clawed frog)	slc13a3	NP_001015776.1
Bos taurus (cattle)	SLC13A3	NP_001073757.1
Pan troglodytes (chimpanzee)	SLC13A3	XP_514696.2
Mus musculus (house mouse)	Slc13a3	NP_473396.1
Gallus gallus (chicken)	SLC13A3	XP_003642529.1

Gene Ontology
Bibliography

Related articles in PubMed

High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H
Nucleic acids research42(Database issue)D802-9(2014 Jan)

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH
PloS one6(2)e17286(2011 Feb)

3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3.
Stellmer F, Keyser B, Burckhardt BC, Koepsell H, Streichert T, Glatzel M, Jabs S, Thiem J, Herdering W, Koeller DM, Goodman SI, Lukacs Z, Ullrich K, Burckhardt G, Braulke T, M?hlhausen C
Journal of molecular medicine (Berlin, Germany)85(7)763-70(2007 Jul)

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Willnow T, Antignac C, Br?ndli A, Christensen E, Cox R, Davidson D, Davies J, Devuyst O, Eichele G, Hastie N, Verroust P, Schedl A, Meij I
Organogenesis2(2)42-7(2005 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

demonstrate the membrane translocation of 3OH-GA mediated by NaDC3 and the cis-inhibitory effect on OCT2-mediated transport of cations
Title: 3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3.

The following Slc13a3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc13a3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09526	NM_054055.2 Latest version!	Mus musculus solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (Slc13a3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$349.30 $499.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc13a3 ( NM_054055.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_473396.1 Mus musculus solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (Slc13a3), mRNA.

Price & Availability↑

CloneID	OMu09526
Clone ID Related Accession (Same CDS sequence)	NM_054055.2
Accession Version	NM_054055.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Mus musculus(house mouse)
Product	solute carrier family 13 member 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL591064.11. On Mar 21, 2007 this sequence version replaced NM_054055.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AF306491.1, AK085326.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCGC TGGCGGCGCT GGCCAAGAAG GTGTGGAGCG CGCGGCGCCT CCTGGTGCTG 
CTGCTGGTGC CGCTGGCTCT GCTGCCCATT CTCTTCGCCC TGCCGCCCAA GGAAGGCCGA 
TGCCTCTATG TCATCCTGCT CATGGCGGTG TACTGGTGCA CAGAGGCCCT GCCCCTGTCA 
GTGACAGCTC TTCTGCCCAT CATCCTCTTC CCCTTCATGG GCATTCTGCC CTCCAGCAAG 
GTCTGCCCCC AGTACTTCCT CGACACCAAC TTCCTCTTCC TTAGCGGCCT GATCATGGCC 
AGCGCCATAG AGGAATGGAA CTTGCACCGG AGAATCGCCC TCAAGGTCCT CATGCTGGTT 
GGGGTCCAGC CTGCAAGGCT CATCCTGGGG ATGATGGTGA CCACGTCATT CCTGTCTATG 
TGGCTGAGCA ACACGGCCTC CACCGCAATG ATGCTACCCA TTGCCAGTGC CATCCTCAAG 
AGCCTCTTTG GCCAGCGCGA AGCTCGGAAG GACCTTCCCC GGGAAGGCGA CGAGAGCACA 
GCTGCTGTGC AGGGAAATGG ACTGCGAACA GTGCCCACGG AGATGCAGTT TCTTGCCAGT 
TCGGAAGGAG GTCACACTGA GGATGCAGAG GCCCCGATGG AGCTGCCTGA TGACTCCAAG 
GAGGAGGAAC ACCGCAGAAA CATCTGGAAG GGCTTCCTCA TTTCCATTCC TTACTCTGCC 
AGCATTGGGG GCACTGCCAC CCTCACGGGC ACCGCCCCCA ACCTCATCCT GCTCGGCCAG 
CTCAAGAGTT TCTTCCCACA GTGTGATGTG GTGAATTTTG GCTCCTGGTT CATCTTCGCC 
TTCCCTCTCA TGCTGTTGTT CCTACTGGTG GGCTGGCTCT GGATCTCCTT CCTCTATGGT 
GGAATGAGCT GGAGAAGTTG GAGGAAGAAG AAATCCAAGA TACGAGCTGA CGCAGAGGAT 
CAGGCTAAAG CGGTGATCCA GGAGGAGTTC CAGAACCTGG GGCCCATCAA GTTTGCTGAA 
CAGGCCGTCT TCATCTTGTT CTGCACGTTT GCCATCCTCC TCTTCTCCCG GGACCCCAAG 
TTCATCCCTG GCTGGGCCAG CCTCTTCGCC CCTGGGTTTG TCTCGGATGC TGTCACCGGT 
GTGGCCATTG TCACCATCCT GTTCTTCTTC CCTTCCCAGA AGCCCTCACT CAAGTGGTGG 
TTTGACTTCA AAGCTCCCAA CTCGGAGACG GAGCCCCTGC TGAGCTGGAA GAAGGCCCAG 
GAGACAGTGC CCTGGAACAT TATCCTTCTT CTAGGAGGTG GCTTTGCCAT GGCCAAGGGC 
TGTGAGGAGT CTGGGCTATC AGCATGGATC GGTGGACAGC TGCACCCCCT GGAGCATGTC 
CCCCCACTGC TGGCAGTGCT GCTCATCACC GTGGTCATCG CCTTCTTCAC GGAGTTTGCC 
AGCAACACGG CCACCATCAT CATCTTCCTG CCCGTCCTGG CAGAGCTGGC CATCCGACTG 
CATGTGCACC CCTTGTACCT GATGATCCCA GGCACGGTCG GCTGCTCCTA CGCCTTCATG 
CTGCCGGTCT CAACACCCCC AAACTCCATT GCCTTCTCTA CTGGACACTT GCTGGTCAAA 
GACATGGTGC GGACGGGCCT GCTGATGAAC CTGATGGGTG TCCTGCTGCT CAGCCTGGCC 
ATGAACACCT GGGCACAGAC CATCTTCCAG CTGGGCACCT TCCCAGACTG GGCCAACACC 
CATGCTGCTA ACGCCACCGC ACTGCCACCA GCCTTGACCA ACAACACAGT TCAAACCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_473396.1
CDS	37..1839
Translation	MAALAALAKKVWSARRLLVLLLVPLALLPILFALPPKEGRCLYVILLMAVYWCTEALPLSVTALLPIILFPFMGILPSSKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKVLMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIASAILKSLFGQREARKDLPREGDESTAAVQGNGLRTVPTEMQFLASSEGGHTEDAEAPMELPDDSKEEEHRRNIWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQCDVVNFGSWFIFAFPLMLLFLLVGWLWISFLYGGMSWRSWRKKKSKIRADAEDQAKAVIQEEFQNLGPIKFAEQAVFILFCTFAILLFSRDPKFIPGWASLFAPGFVSDAVTGVAIVTILFFFPSQKPSLKWWFDFKAPNSETEPLLSWKKAQETVPWNIILLLGGGFAMAKGCEESGLSAWIGGQLHPLEHVPPLLAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLHVHPLYLMIPGTVGCSYAFMLPVSTPPNSIAFSTGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWAQTIFQLGTFPDWANTHAANATALPPALTNNTVQTF

Target ORF information:

RefSeq Version	NM_054055.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (Slc13a3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_054055.2

ORF Insert Sequence:

ATGGCGGCGC TGGCGGCGCT GGCCAAGAAG GTGTGGAGCG CGCGGCGCCT CCTGGTGCTG 
CTGCTGGTGC CGCTGGCTCT GCTGCCCATT CTCTTCGCCC TGCCGCCCAA GGAAGGCCGA 
TGCCTCTATG TCATCCTGCT CATGGCGGTG TACTGGTGCA CAGAGGCCCT GCCCCTGTCA 
GTGACAGCTC TTCTGCCCAT CATCCTCTTC CCCTTCATGG GCATTCTGCC CTCCAGCAAG 
GTCTGCCCCC AGTACTTCCT CGACACCAAC TTCCTCTTCC TTAGCGGCCT GATCATGGCC 
AGCGCCATAG AGGAATGGAA CTTGCACCGG AGAATCGCCC TCAAGGTCCT CATGCTGGTT 
GGGGTCCAGC CTGCAAGGCT CATCCTGGGG ATGATGGTGA CCACGTCATT CCTGTCTATG 
TGGCTGAGCA ACACGGCCTC CACCGCAATG ATGCTACCCA TTGCCAGTGC CATCCTCAAG 
AGCCTCTTTG GCCAGCGCGA AGCTCGGAAG GACCTTCCCC GGGAAGGCGA CGAGAGCACA 
GCTGCTGTGC AGGGAAATGG ACTGCGAACA GTGCCCACGG AGATGCAGTT TCTTGCCAGT 
TCGGAAGGAG GTCACACTGA GGATGCAGAG GCCCCGATGG AGCTGCCTGA TGACTCCAAG 
GAGGAGGAAC ACCGCAGAAA CATCTGGAAG GGCTTCCTCA TTTCCATTCC TTACTCTGCC 
AGCATTGGGG GCACTGCCAC CCTCACGGGC ACCGCCCCCA ACCTCATCCT GCTCGGCCAG 
CTCAAGAGTT TCTTCCCACA GTGTGATGTG GTGAATTTTG GCTCCTGGTT CATCTTCGCC 
TTCCCTCTCA TGCTGTTGTT CCTACTGGTG GGCTGGCTCT GGATCTCCTT CCTCTATGGT 
GGAATGAGCT GGAGAAGTTG GAGGAAGAAG AAATCCAAGA TACGAGCTGA CGCAGAGGAT 
CAGGCTAAAG CGGTGATCCA GGAGGAGTTC CAGAACCTGG GGCCCATCAA GTTTGCTGAA 
CAGGCCGTCT TCATCTTGTT CTGCACGTTT GCCATCCTCC TCTTCTCCCG GGACCCCAAG 
TTCATCCCTG GCTGGGCCAG CCTCTTCGCC CCTGGGTTTG TCTCGGATGC TGTCACCGGT 
GTGGCCATTG TCACCATCCT GTTCTTCTTC CCTTCCCAGA AGCCCTCACT CAAGTGGTGG 
TTTGACTTCA AAGCTCCCAA CTCGGAGACG GAGCCCCTGC TGAGCTGGAA GAAGGCCCAG 
GAGACAGTGC CCTGGAACAT TATCCTTCTT CTAGGAGGTG GCTTTGCCAT GGCCAAGGGC 
TGTGAGGAGT CTGGGCTATC AGCATGGATC GGTGGACAGC TGCACCCCCT GGAGCATGTC 
CCCCCACTGC TGGCAGTGCT GCTCATCACC GTGGTCATCG CCTTCTTCAC GGAGTTTGCC 
AGCAACACGG CCACCATCAT CATCTTCCTG CCCGTCCTGG CAGAGCTGGC CATCCGACTG 
CATGTGCACC CCTTGTACCT GATGATCCCA GGCACGGTCG GCTGCTCCTA CGCCTTCATG 
CTGCCGGTCT CAACACCCCC AAACTCCATT GCCTTCTCTA CTGGACACTT GCTGGTCAAA 
GACATGGTGC GGACGGGCCT GCTGATGAAC CTGATGGGTG TCCTGCTGCT CAGCCTGGCC 
ATGAACACCT GGGCACAGAC CATCTTCCAG CTGGGCACCT TCCCAGACTG GGCCAACACC 
CATGCTGCTA ACGCCACCGC ACTGCCACCA GCCTTGACCA ACAACACAGT TCAAACCTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High-throughput discovery of novel developmental phenotypes.
Nature537(7621)508-514(2016 09)
Dickinson ME,Flenniken AM,Ji X,Teboul L,Wong MD,White JK,Meehan TF,Weninger WJ,Westerberg H,Adissu H,Baker CN,Bower L,Brown JM,Caddle LB,Chiani F,Clary D,Cleak J,Daly MJ,Denegre JM,Doe B,Dolan ME,Edie SM,Fuchs H,Gailus-Durner V,Galli A,Gambadoro A,Gallegos J,Guo S,Horner NR,Hsu CW,Johnson SJ,Kalaga S,Keith LC,Lanoue L,Lawson TN,Lek M,Mark M,Marschall S,Mason J,McElwee ML,Newbigging S,Nutter LM,Peterson KA,Ramirez-Solis R,Rowland DJ,Ryder E,Samocha KE,Seavitt JR,Selloum M,Szoke-Kovacs Z,Tamura M,Trainor AG,Tudose I,Wakana S,Warren J,Wendling O,West DB,Wong L,Yoshiki A,,,,,,,,,MacArthur DG,Tocchini-Valentini GP,Gao X,Flicek P,Bradley A,Skarnes WC,Justice MJ,Parkinson HE,Moore M,Wells S,Braun RE,Svenson KL,de Angelis MH,Herault Y,Mohun T,Mallon AM,Henkelman RM,Brown SD,Adams DJ,Lloyd KC,McKerlie C,Beaudet AL,Bu?an M,Murray SA

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Nucleic acids research42(Database issue)D802-9(2014 Jan)
Koscielny G,Yaikhom G,Iyer V,Meehan TF,Morgan H,Atienza-Herrero J,Blake A,Chen CK,Easty R,Di Fenza A,Fiegel T,Grifiths M,Horne A,Karp NA,Kurbatova N,Mason JC,Matthews P,Oakley DJ,Qazi A,Regnart J,Retha A,Santos LA,Sneddon DJ,Warren J,Westerberg H,Wilson RJ,Melvin DG,Smedley D,Brown SD,Flicek P,Skarnes WC,Mallon AM,Parkinson H

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
PloS one6(2)e17286(2011 Feb)
Thiagarajan RD,Georgas KM,Rumballe BA,Lesieur E,Chiu HS,Taylor D,Tang DT,Grimmond SM,Little MH

3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3.
Journal of molecular medicine (Berlin, Germany)85(7)763-70(2007 Jul)
Stellmer F,Keyser B,Burckhardt BC,Koepsell H,Streichert T,Glatzel M,Jabs S,Thiem J,Herdering W,Koeller DM,Goodman SI,Lukacs Z,Ullrich K,Burckhardt G,Braulke T,M?hlhausen C

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Organogenesis2(2)42-7(2005 Apr)
Willnow T,Antignac C,Br?ndli A,Christensen E,Cox R,Davidson D,Davies J,Devuyst O,Eichele G,Hastie N,Verroust P,Schedl A,Meij I

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Slc13a3 cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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