Gene Symbol | pha-4 |
Entrez Gene ID | 180357 |
Full Name | Defective pharyngeal development protein 4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pha-4 cDNA ORF clone
Gene Symbol | pha-4 |
Entrez Gene ID | 180357 |
Full Name | Defective pharyngeal development protein 4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001047649.3 | NP_001041114.1 | Defective pharyngeal development protein 4 |
NM_001047650.3 | NP_001041115.1 | Defective pharyngeal development protein 4 |
NM_001047651.4 | NP_001041116.1 | Defective pharyngeal development protein 4 |
NM_001047651.3 | NP_001041116.1 | Defective pharyngeal development protein 4 |
NM_001047649.2 | NP_001041114.1 | Defective pharyngeal development protein 4 |
NM_001047650.2 | NP_001041115.1 | Defective pharyngeal development protein 4 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Reduced signaling through the insulin-like receptor daf-2/InsR in the maternal soma causes constitutively large progeny, and its effector daf-16/FoxO is required for this effect. nhr-49/Hnf4, pha-4/FoxA, and skn-1/Nrf also regulate progeny-size plasticity. Genetic analysis suggests that insulin-like signaling controls progeny size in part through regulation of nhr-49/Hnf4, and that pha-4/FoxA and skn-1/Nrf function
Title: Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance.
these results suggest that Pol II recruitment, in addition to chromatin opening, is an important feature of PHA-4 pioneer factor activity.
Title: TRANSCRIPTION. Recruitment of RNA polymerase II by the pioneer transcription factor PHA-4.
A network analysis of aging-associated miRNAs connected to transcription factors PHA-4/FOXA and SKN-1/Nrf revealed extensive regulatory interactions between PHA-4, SKN-1, and miRNAs undergoing dietary restriction.
Title: MicroRNAs mediate dietary-restriction-induced longevity through PHA-4/FOXA and SKN-1/Nrf transcription factors.
results suggest that PHA-4 employs feed-forward loops to fine-tune gene expression and instil robustness in the system during energy crisis.
Title: PHA-4/FOXA-regulated microRNA feed forward loops during Caenorhabditis elegans dietary restriction.
Suppression of misfolding in muscle cells is achieved not only by enhanced expression of HSP90 in muscle cells but also by elevated expression of HSP90 (Daf-21) in intestine or neuronal cells. This cell-nonautonomous control of HSP90 expression relies upon transcriptional feedback between somatic tissues that is regulated by the FoxA transcription factor PHA-4.
Title: Regulation of organismal proteostasis by transcellular chaperone signaling.
The following pha-4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pha-4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa346028 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047650.3 , NM_001047650.2 | |
Accession Version | NM_001047650.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Defective pharyngeal development protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001047650.2. COMPLETENESS: incomplete on the 5' end. |
1 | ATGTTGCCAA ATGGAACCAC TTCTGGGACC TCCGACACGG GAAATCAGGT GCCTGCCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041115.1 |
CDS | 1..1329 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047650.3 |
1 | ATGTTGCCAA ATGGAACCAC TTCTGGGACC TCCGACACGG GAAATCAGGT GCCTGCCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346028 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047650.3 , NM_001047650.2 | |
Accession Version | NM_001047650.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Defective pharyngeal development protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_001047650.1. COMPLETENESS: incomplete on both ends. |
1 | ATGTTGCCAA ATGGAACCAC TTCTGGGACC TCCGACACGG GAAATCAGGT GCCTGCCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041115.1 |
CDS | 1..1329 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047650.2 |
1 | ATGTTGCCAA ATGGAACCAC TTCTGGGACC TCCGACACGG GAAATCAGGT GCCTGCCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346029 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047651.4 , NM_001047651.3 | |
Accession Version | NM_001047651.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1236bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Defective pharyngeal development protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001047651.3. |
1 | ATGAACGCTC AGGACTATCT GCCGACGTAT TCTAATACTA CGTTAAACTA CCAACCATAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041116.1 |
CDS | 4..1239 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047651.4 |
1 | ATGAACGCTC AGGACTATCT GCCGACGTAT TCTAATACTA CGTTAAACTA CCAACCATAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346029 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047651.4 , NM_001047651.3 | |
Accession Version | NM_001047651.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1236bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Defective pharyngeal development protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_001047651.2. COMPLETENESS: incomplete on both ends. |
1 | ATGAACGCTC AGGACTATCT GCCGACGTAT TCTAATACTA CGTTAAACTA CCAACCATAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041116.1 |
CDS | 1..1236 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047651.3 |
1 | ATGAACGCTC AGGACTATCT GCCGACGTAT TCTAATACTA CGTTAAACTA CCAACCATAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa345948 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047649.3 , NM_001047649.2 | |
Accession Version | NM_001047649.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Defective pharyngeal development protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001047649.2. COMPLETENESS: incomplete on the 5' end. |
1 | ATGACATCGC CATCCAGTGA TGAGGACATT ATTGATATAA GGGTCATCAA AGAGGAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041114.1 |
CDS | 1..1521 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047649.3 |
1 | ATGACATCGC CATCCAGTGA TGAGGACATT ATTGATATAA GGGTCATCAA AGAGGAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa345948 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047649.3 , NM_001047649.2 | |
Accession Version | NM_001047649.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Defective pharyngeal development protein 4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_001047649.1. COMPLETENESS: incomplete on both ends. |
1 | ATGACATCGC CATCCAGTGA TGAGGACATT ATTGATATAA GGGTCATCAA AGAGGAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001041114.1 |
CDS | 1..1521 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047649.2 |
1 | ATGACATCGC CATCCAGTGA TGAGGACATT ATTGATATAA GGGTCATCAA AGAGGAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |