Gene Symbol | RPH1 |
Entrez Gene ID | 856916 |
Full Name | Rph1p |
Synonyms | KDM4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RPH1 cDNA ORF clone
Gene Symbol | RPH1 |
Entrez Gene ID | 856916 |
Full Name | Rph1p |
Synonyms | KDM4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179059.1 | NP_011096.1 | Rph1p |
Saccharomyces cerevisiae (baker's yeast) | RPH1 | NP_011096.1 |
Eremothecium gossypii | AGOS_AGR117C | NP_986783.2 |
Kluyveromyces lactis | KLLA0C17710g | XP_452991.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
led to the identification of Rph1 as a master transcriptional regulator of autophagy
Title: Rph1 mediates the nutrient-limitation signaling pathway leading to transcriptional activation of autophagy.
Rph1/KDM4 mediates nutrient-limitation signaling that leads to the transcriptional induction of autophagy.
Title: Rph1/KDM4 mediates nutrient-limitation signaling that leads to the transcriptional induction of autophagy.
activity of Rph1 is not essential for its role in the transcriptional response to nutrient signaling
Title: The histone demethylase activity of Rph1 is not essential for its role in the transcriptional response to nutrient signaling.
Our findings confirm the regulatory role of Rph1 as a transcriptional repressor and reveal that Rph1 might be a regulatory node connecting different signaling pathways responding to environmental stresses.
Title: Dissociation of the H3K36 demethylase Rph1 from chromatin mediates derepression of environmental stress-response genes under genotoxic stress in Saccharomyces cerevisiae.
these results show that of the JmjC-containing proteins, Rph1 is the demethylase that is specific for histone H3K36 trimethylation during transcription elongation in vivo.
Title: Role of yeast JmjC-domain containing histone demethylases in actively transcribed regions.
The following RPH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05664 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179059.1 | |
Accession Version | NM_001179059.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2391bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Rph1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGACGAAAC TAATCGCTCC TTCAGAAATC GTGGGCGGAG TGCCCGTCTT CAAACCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011096.1 |
CDS | 1..2391 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACGAAAC TAATCGCTCC TTCAGAAATC GTGGGCGGAG TGCCCGTCTT CAAACCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |