Gene Symbol | SRB4 |
Entrez Gene ID | 856743 |
Full Name | Srb4p |
Synonyms | MED17 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SRB4 cDNA ORF clone
Gene Symbol | SRB4 |
Entrez Gene ID | 856743 |
Full Name | Srb4p |
Synonyms | MED17 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178913.1 | NP_010939.1 | Srb4p |
Kluyveromyces lactis | KLLA0D10802g | XP_453543.1 |
Saccharomyces cerevisiae (baker's yeast) | SRB4 | NP_010939.1 |
Eremothecium gossypii | AGOS_ABR165W | NP_983113.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that Med17(Srb4) are direct targets of mediator histone H4 tail interactions.
Title: Med5(Nut1) and Med17(Srb4) are direct targets of mediator histone H4 tail interactions.
identifed direct physical interaction between the Rpb3 Pol II subunit and the Mediator subunit, Med17; findings suggest a direct interaction between Mediator and Pol II is generally required for transcription of class II genes in eukaryotes
Title: Direct interaction of RNA polymerase II and mediator required for transcription in vivo.
characterize Mediator from cells carrying the srb4-138 allele and find that the Mediator complex consistently breaks apart at the head/middle domain boundary even at lower temperatures
Title: The classical srb4-138 mutant allele causes dissociation of yeast Mediator.
identified as a general transcription factor, comparable in importance to RNA polymerase II and other general factors for the initiation of transcription
Title: Mediator as a general transcription factor.
The following SRB4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SRB4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05511 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178913.1 | |
Accession Version | NM_001178913.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2064bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Srb4p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGACAACGG AAGATCCAGA TTCAAATCAC TTAAGTTCCG AAACTGGCAT TAAATTGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010939.1 |
CDS | 1..2064 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178913.1 |
1 | ATGACAACGG AAGATCCAGA TTCAAATCAC TTAAGTTCCG AAACTGGCAT TAAATTGGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |