Gene Symbol | KAR3 |
Entrez Gene ID | 856263 |
Full Name | Kar3p |
Synonyms | OSR11 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » KAR3 cDNA ORF clone
Gene Symbol | KAR3 |
Entrez Gene ID | 856263 |
Full Name | Kar3p |
Synonyms | OSR11 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001184238.1 | NP_015467.1 | Kar3p |
Kluyveromyces lactis | KLLA0B10956g | XP_452016.1 |
Eremothecium gossypii | AGOS_AGR253W | NP_986919.1 |
Saccharomyces cerevisiae (baker's yeast) | KAR3 | NP_015467.1 |
Oryza sativa (rice) | Os03g0862200 | NP_001051987.2 |
Oryza sativa (rice) | Os07g0105700 | NP_001058699.1 |
Schizosaccharomyces pombe (fission yeast) | klp2 | NP_593458.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The kinesin-14 motor protein complex (Cik1-Kar3) cooperates with chromatin remodellers to mediate interactions between subtelomeric double-strand breaks and the Nup84 nuclear pore complex to ensure cell survival via break-induced replication.
Title: Perinuclear tethers license telomeric DSBs for a broad kinesin- and NPC-dependent DNA repair process.
findings provide an example for a non-conventional translocation mechanism and can explain how Kar3 substitutes for key functions of Dynein in the yeast nucleus
Title: Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3.
Cryoelectron microscopy generated 3-D structure of Kar3Cik1 complexed to microtubules in various nucleotide states.
Title: Common mechanistic themes for the powerstroke of kinesin-14 motors.
Kar3, with the help of its light chain, Cik1, is anchored during mating to the SPB component Spc72 that also serves as a nucleator and anchor for microtubules via their minus ends.
Title: Spindle pole body-anchored Kar3 drives the nucleus along microtubules from another nucleus in preparation for nuclear fusion during yeast karyogamy.
Neck rotation and neck mimic docking in Vik1 and Cik1 is a structural mechanism for communication with Kar3.
Title: Neck rotation and neck mimic docking in the noncatalytic Kar3-associated protein Vik1.
The following KAR3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KAR3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05088 | |
Clone ID Related Accession (Same CDS sequence) | NM_001184238.1 | |
Accession Version | NM_001184238.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Kar3p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAATCAC TTCCACGTAC TCCCACAAAA GGCAGATCTA CGCAGCATCT CTCGACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015467.1 |
CDS | 1..2190 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001184238.1 |
1 | ATGGAATCAC TTCCACGTAC TCCCACAAAA GGCAGATCTA CGCAGCATCT CTCGACACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |