Gene Symbol | ALE1 |
Entrez Gene ID | 854346 |
Full Name | lysophospholipid acyltransferase |
Synonyms | LCA1,LPT1,SLC4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » ALE1 cDNA ORF clone
Gene Symbol | ALE1 |
Entrez Gene ID | 854346 |
Full Name | lysophospholipid acyltransferase |
Synonyms | LCA1,LPT1,SLC4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183594.1 | NP_014818.1 | lysophospholipid acyltransferase |
Bos taurus (cattle) | MBOAT2 | XP_002691577.3 |
Gallus gallus (chicken) | MBOAT2 | NP_001026261.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007567 | XP_308306.4 |
Magnaporthe oryzae (rice blast fungus) | MGG_08856 | XP_003713879.1 |
Arabidopsis thaliana (thale cress) | AT1G12640 | NP_172724.2 |
Oryza sativa (rice) | Os02g0676000 | NP_001047723.1 |
Homo sapiens (human) | MBOAT2 | NP_620154.2 |
Pan troglodytes (chimpanzee) | MBOAT2 | XP_515289.2 |
Mus musculus (house mouse) | Mboat2 | NP_080313.2 |
Danio rerio (zebrafish) | mboat2b | NP_001265531.1 |
Saccharomyces cerevisiae (baker's yeast) | ALE1 | NP_014818.1 |
Xenopus tropicalis (tropical clawed frog) | mboat2 | NP_001096155.1 |
Rattus norvegicus (Norway rat) | Mboat2 | NP_001101486.2 |
Eremothecium gossypii | AGOS_AGR271C | NP_986937.2 |
Neurospora crassa | NCU06194 | XP_963006.1 |
Arabidopsis thaliana (thale cress) | AT1G63050 | NP_176493.1 |
MBOAT2 | XP_001083917.2 | |
Canis lupus familiaris (dog) | MBOAT2 | XP_005630649.1 |
Danio rerio (zebrafish) | mboat2a | XP_699295.3 |
Caenorhabditis elegans (roundworm) | mboa-3 | NP_508937.1 |
Caenorhabditis elegans (roundworm) | mboa-4 | NP_001255544.1 |
Drosophila melanogaster (fruit fly) | oys | NP_610546.1 |
Caenorhabditis elegans (roundworm) | mboa-5 | NP_503057.1 |
Kluyveromyces lactis | KLLA0F20163g | XP_455985.1 |
Schizosaccharomyces pombe (fission yeast) | SPBC16A3.10 | NP_596779.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
D146 and E297 act in conjunction with H382 as nucleophiles that attack the hydroxyl group in lysophospholipids in a general acid/base mechanism in Lpt1.
Title: Saccharomyces cerevisiae lysophospholipid acyltransferase, Lpt1, requires Asp146 and Glu297 for catalysis.
pology of 1-acyl-sn-glycerol-3-phosphate acyltransferases SLC1 and ALE1 and related membrane-bound O-acyltransferases (MBOATs) of Saccharomyces cerevisiae.
Title: Topology of 1-acyl-sn-glycerol-3-phosphate acyltransferases SLC1 and ALE1 and related membrane-bound O-acyltransferases (MBOATs) of Saccharomyces cerevisiae.
The ELM pathway for lyso-PtdEtn requires the action of Dnf1p and Dnf2p and their requisite beta-subunit, Lem3p, for the active uptake of lyso-PtdEtn. In addition, Ale1p, mediates the acylation of the imported lysolipid to form PtdEtn.
Title: Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation.
in concert with Slc1, Lpt1 plays a central role in Phosphatidic acid biosynthesis, which is essential for cell viability.
Title: LPT1 encodes a membrane-bound O-acyltransferase involved in the acylation of lysophospholipids in the yeast Saccharomyces cerevisiae.
Identification of LCA1 provides an essential molecular tool for further study of Lands cycle in phosphatidylcholine turnover
Title: The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover.
The following ALE1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALE1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03474 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183594.1 | |
Accession Version | NM_001183594.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1860bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | lysophospholipid acyltransferase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTACAATC CTGTGGACGC TGTTTTAACA AAGATAATTA CCAACTATGG GATTGATAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014818.1 |
CDS | 1..1860 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183594.1 |
1 | ATGTACAATC CTGTGGACGC TGTTTTAACA AAGATAATTA CCAACTATGG GATTGATAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |