Gene Symbol | DIA2 |
Entrez Gene ID | 854247 |
Full Name | DNA-binding SCF ubiquitin ligase subunit DIA2 |
Synonyms | YOR29-31 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » DIA2 cDNA ORF clone
Gene Symbol | DIA2 |
Entrez Gene ID | 854247 |
Full Name | DNA-binding SCF ubiquitin ligase subunit DIA2 |
Synonyms | YOR29-31 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183499.1 | NP_014723.2 | DNA-binding SCF ubiquitin ligase subunit DIA2 |
Saccharomyces cerevisiae (baker's yeast) | DIA2 | NP_014723.2 |
Kluyveromyces lactis | KLLA0A07579g | XP_451337.1 |
Eremothecium gossypii | AGOS_ADR230W | NP_984326.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Dia2-dependent degradation of Mrc1 is required for replication fork restart in a pathway that includes Sgs1 and Mph1.
Title: Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks.
The tethering of SCF(Dia2) to the replisome progression complex increases the efficiency of ubiquitylation of the Mcm7 subunit of CMG. Correspondingly, loss of tethering is synthetic lethal in combination with a disassembly-defective allele of CDC48.
Title: Tethering of SCF(Dia2) to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase.
the ubiquitin ligase known as SCF(Dia2) promotes ubiquitylation of CMG helicase during the final stages of chromosome replication in Saccharomyces cerevisiae.
Title: Cdc48 and a ubiquitin ligase drive disassembly of the CMG helicase at the end of DNA replication.
Dia2 mediates Mrc1 degradation to help cells resume the cell cycle during recovery from MMS-induced DNA damage in S-phase.
Title: The Saccharomyces cerevisiae F-box protein Dia2 is a mediator of S-phase checkpoint recovery from DNA damage.
Tom1 and the Dia2 control Cdc6 degradation in G1 phase.
Title: The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phase.
The following DIA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DIA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03387 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183499.1 | |
Accession Version | NM_001183499.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2199bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | DNA-binding SCF ubiquitin ligase subunit DIA2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTTCCC CAGGGAATTC AGGCGTGGCT ATAGATTCTA CCGTTCTGAA AGCAATTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014723.2 |
CDS | 1..2199 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTCTTCCC CAGGGAATTC AGGCGTGGCT ATAGATTCTA CCGTTCTGAA AGCAATTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |