Gene Symbol | CRN1 |
Entrez Gene ID | 851148 |
Full Name | Crn1p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CRN1 cDNA ORF clone
Gene Symbol | CRN1 |
Entrez Gene ID | 851148 |
Full Name | Crn1p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182317.1 | NP_013533.1 | Crn1p |
Danio rerio (zebrafish) | coro1cb | XP_005172017.1 |
Pan troglodytes (chimpanzee) | CORO1C | XP_003313960.1 |
Bos taurus (cattle) | CORO1C | NP_001075059.1 |
Gallus gallus (chicken) | CORO1C | NP_001264798.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005891 | XP_001688746.1 |
Eremothecium gossypii | AGOS_AER114W | NP_984974.1 |
Neurospora crassa | NCU00202 | XP_956587.1 |
Xenopus tropicalis (tropical clawed frog) | coro1c | NP_989383.1 |
Danio rerio (zebrafish) | coro1ca | NP_958452.1 |
Caenorhabditis elegans (roundworm) | cor-1 | NP_741270.1 |
Kluyveromyces lactis | KLLA0D02530g | XP_453181.1 |
Drosophila melanogaster (fruit fly) | coro | NP_001260743.1 |
Saccharomyces cerevisiae (baker's yeast) | CRN1 | NP_013533.1 |
Schizosaccharomyces pombe (fission yeast) | crn1 | NP_593175.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06389 | XP_003717184.1 |
Homo sapiens (human) | CORO1C | NP_001098707.1 |
CORO1C | XP_002798812.1 | |
Canis lupus familiaris (dog) | CORO1C | XP_003433441.1 |
Mus musculus (house mouse) | Coro1c | NP_035909.2 |
Rattus norvegicus (Norway rat) | Coro1c | NP_001102797.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Johnston M, Hillier L, Riles L, Albermann K, Andr? B, Ansorge W, Benes V, Br?ckner M, Delius H, Dubois E, D?sterh?ft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, K?tter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD
Nature387(6632 Suppl)87-90(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Using multi-color total internal reflection fluorescence microscopy, the study shows that Crn1 enhances Cof1-mediated severing by accelerating Cof1 binding to actin filament sides.
Title: Coronin Enhances Actin Filament Severing by Recruiting Cofilin to Filament Sides and Altering F-Actin Conformation.
The study reports cryo-EM structures for ADP-bound and ADP-beryllium fluoride (ADP-BeFx, an ADP-Pi mimic)-bound actin filaments in complex with the beta-propeller domain of yeast coronin 1 (crn1), at 8.6-A resolution.
Title: Cryo-EM reveals different coronin binding modes for ADP- and ADP-BeFx actin filaments.
development of a direct tethering recruitment model for activation of Arp2/3 complex by Crn1
Title: Mechanism of a concentration-dependent switch between activation and inhibition of Arp2/3 complex by coronin.
Conservation of the actin-binding surfaces across distant species and in all three major classes of coronin isoforms suggests that the nature of the coronin-actin association may be similar in other family members.
Title: Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis.
Results suggest that that coronin polarizes the spatial distribution and activity of cofilin to promote selective disassembly of older actin filaments.
Title: Coronin switches roles in actin disassembly depending on the nucleotide state of actin.
The following CRN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CRN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00742 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182317.1 | |
Accession Version | NM_001182317.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1956bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Crn1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001144). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGTGGAA AATTTGTTCG TGCTTCTAAA TATAGACACG TCTTTGGCCA AGCGGCCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013533.1 |
CDS | 1..1956 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182317.1 |
1 | ATGAGTGGAA AATTTGTTCG TGCTTCTAAA TATAGACACG TCTTTGGCCA AGCGGCCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. |
Life with 6000 genes. |