Gene Symbol | SEI1 |
Entrez Gene ID | 851120 |
Full Name | seipin |
Synonyms | FLD1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SEI1 cDNA ORF clone
Gene Symbol | SEI1 |
Entrez Gene ID | 851120 |
Full Name | seipin |
Synonyms | FLD1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182292.3 | NP_013508.3 | seipin |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Johnston M, Hillier L, Riles L, Albermann K, Andr? B, Ansorge W, Benes V, Br?ckner M, Delius H, Dubois E, D?sterh?ft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, K?tter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD
Nature387(6632 Suppl)87-90(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Proper droplet formation requires the collaboration of Sei1p and Ldb16.
Title: Dissecting seipin function: the localized accumulation of phosphatidic acid at ER/LD junctions in the absence of seipin is suppressed by Sei1p(?Nterm) only in combination with Ldb16p.
The Fld1/Ldb16 complex facilitates the establishment of lipid droplet (LD) identity by acting as a diffusion barrier at the endoplasmic reticulum-LD contact sites.
Title: The seipin complex Fld1/Ldb16 stabilizes ER-lipid droplet contact sites.
Fld1(seipin)-Ldb16 complex affects phosphatidic acid homeostasis at an lipid droplets-forming subdomain of the nuclear envelope.
Title: Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast.
Seipin has dissectible roles in both promoting early lipid droplet (LD) initiation and in regulating LD morphology.
Title: Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology.
The stability of Ldb16 requires Fld1, as Ldb16 is subjected to ER-associated degradation (ERAD) in the absence of Fld1 but is stabilized when Fld1 is present.
Title: Control of lipid droplet size in budding yeast requires the collaboration between Fld1 and Ldb16.
The following SEI1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SEI1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00717 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182292.3 | |
Accession Version | NM_001182292.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | seipin | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001144). On Jul 30, 2012 this sequence version replaced NM_001182292.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAAAATCA ATGTATCCCG TCCATTACAG TTTTTACAAT GGAGTTCATA TATTGTTGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013508.3 |
CDS | 1..858 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182292.3 |
1 | ATGAAAATCA ATGTATCCCG TCCATTACAG TTTTTACAAT GGAGTTCATA TATTGTTGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. |
Life with 6000 genes. |