Gene Symbol | ECL1 |
Entrez Gene ID | 9406964 |
Full Name | extender of the chronological lifespan protein Ecl1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe 972h- |
ORF » Species Summary » Schizosaccharomyces pombe 972h- » ECL1 cDNA ORF clone
Gene Symbol | ECL1 |
Entrez Gene ID | 9406964 |
Full Name | extender of the chronological lifespan protein Ecl1 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe 972h- |
mRNA | Protein | Name |
---|---|---|
XM_002788906.2 | XP_002788952.1 | extender of the chronological lifespan protein Ecl1 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
mutated Ecl1 proteins nearly lost the function to extend the chronological life span, suggesting that these four cysteine residues are essential for the Ecl1 protein
Title: Ecl1 is a zinc-binding protein involved in the zinc-limitation-dependent extension of chronological life span in fission yeast.
Ecl1 family proteins may function as zinc sensors in the process of sexual development.
Title: Sexual development of Schizosaccharomyces pombe is induced by zinc or iron limitation through Ecl1 family genes.
we propose that Ecl1-family proteins conduct H2O2 stress resistance and chronological lifespan extension in ctt1+- and prr1+-dependent manner, respectively
Title: Chronological lifespan extension by Ecl1 family proteins depends on Prr1 response regulator in fission yeast.
Hsf1 binds to the upstream DNA region of ecl2 (+) after heat shock in S. pombe.
Title: hsf1 (+) extends chronological lifespan through Ecl1 family genes in fission yeast.
From these results we propose that the effect of Ecl1 overproduction may be mainly linked to and negatively affects the Pka1-dependent pathway.
Title: A novel gene, ecl1(+), extends the chronological lifespan in fission yeast.
The following ECL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ECL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSj00146 | |
Clone ID Related Accession (Same CDS sequence) | XM_002788906.2 | |
Accession Version | XM_002788906.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 243bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2012-12-10 | |
Organism | Schizosaccharomyces pombe 972h- | |
Product | extender of the chronological lifespan protein Ecl1 | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). On Dec 10, 2012 this sequence version replaced XM_002788906.1. Notes: S. pombe (fission yeast) sequence and annotation are available from: (URL, http://www.genedb.org/genedb/pombe/index.jsp) (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CDS are numbered using the following system eg SPAC5H10.01c. SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), .01 (first CDS), c (complementary strand). However, clones may have been reorientated since the original submission, therefore the complementary strand notation may be invalid for strand inference. |
1 | ATGGATTTGG ATTTTTGCAC AGTGTGTGGA GCCACCACTC AGGATGGCAG TTTGTACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_002788952.1 |
CDS | 2784..3026 |
Translation |
Target ORF information:
Target ORF information:
|
XM_002788906.2 |
1 | ATGGATTTGG ATTTTTGCAC AGTGTGTGGA GCCACCACTC AGGATGGCAG TTTGTACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |