Gene Symbol | nse2 |
Entrez Gene ID | 2542312 |
Full Name | Smc5-6 complex non-SMC subunit 2 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
ORF » Species Summary » Schizosaccharomyces pombe » nse2 cDNA ORF clone
Gene Symbol | nse2 |
Entrez Gene ID | 2542312 |
Full Name | Smc5-6 complex non-SMC subunit 2 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe(fission yeast) |
mRNA | Protein | Name |
---|---|---|
XM_001713025.3 | XP_001713077.3 | Smc5-6 complex non-SMC subunit 2 |
NM_001356098.1 | NP_001343015.1 | Smc5-6 complex non-SMC subunit 2 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
role in protecting genome stability against spontaneous Top1-mediated DNA damage
Title: SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability.
Nse2-dependent sumoylation activity has a role in DNA damage responses but not in the essential function of the Smc5-6 complex. [Nse2]
Title: Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.
Nse1, Nse2, and Nse3 are crucial for meiosis. They also play an important role in mitigating the genome destabilizing effects of replication fork stalling. [Nse2]
Title: Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.
Nse1 and Nse2 are non-SMC subunits of the Smc5-6 DNA repair complex. They both interact with Smc5. Nse1 and Nse2 function together with Rhp51 in the homologous recombination repair of DNA double-strand breaks. They are essential proteins. [Nse2]
Title: Novel essential DNA repair proteins Nse1 and Nse2 are subunits of the fission yeast Smc5-Smc6 complex.
The following nse2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nse2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSj03525 | |
Clone ID Related Accession (Same CDS sequence) | XM_001713025.3 | |
Accession Version | XM_001713025.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2013-04-30 | |
Organism | Schizosaccharomyces pombe 972h- | |
Product | Smc5-6 complex non-SMC subunit 2 | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003424). On Dec 10, 2012 this sequence version replaced XM_001713025.2. Notes: S. pombe (fission yeast) sequence and annotation are available from: (URL, http://www.genedb.org/genedb/pombe/index.jsp) (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CDS are numbered using the following system eg SPAC5H10.01c. SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), .01 (first CDS), c (complementary strand). However, clones may have been reorientated since the original submission, therefore the complementary strand notation may be invalid for strand inference. |
1 | ATGAGTGAAG CACAATTAAA AACTTCCTTG GAGGCTTTAA GTCAAAATTT ATTACCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_001713077.3 |
CDS | 202..954 |
Translation |
Target ORF information:
Target ORF information:
|
XM_001713025.3 |
1 | ATGAGTGAAG CACAATTAAA AACTTCCTTG GAGGCTTTAA GTCAAAATTT ATTACCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSc101952 | |
Clone ID Related Accession (Same CDS sequence) | NM_001356098.1 | |
Accession Version | NM_001356098.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | Smc5-6 complex non-SMC subunit 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003424). |
1 | ATGAGTGAAG CACAATTAAA AACTTCCTTG GAGGCTTTAA GTCAAAATTT ATTACCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001343015.1 |
CDS | 202..954 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001356098.1 |
1 | ATGAGTGAAG CACAATTAAA AACTTCCTTG GAGGCTTTAA GTCAAAATTT ATTACCTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |