Loaded IL-22R alpha 1 hFc Chimera, Rat, hFc Tag on ProA-Biosensor can bind Human IL-22, His Tag with an affinity constant of 0.31 μM as determined in BLI assay (Gator® Prime).
Immobilized Human IL-22, His Tag at 5 μg /ml (100 μl/well) on the plate. Dose response curve for IL-22R alpha 1 hFc Chimera, Rat, hFc Tag with the EC50 of 36.6ng/ml determined by ELISA.
The purity of IL-22R alpha 1 hFc Chimera, Rat 1 is greater than 95% as determined by SEC-HPLC.
IL-22R alpha 1 hFc Chimera, Rat on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
IL-22R alpha 1 hFc Chimera, Rat
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3.
| Z06424 | |
|
|
|
| ¥72,752.00 | |
|
|
|
|
|
|
| Ask us a question | |
