IL-13Ra2, His, Rat
IL-13Ra2, His, Rat

Loaded Human IL-13, hFc Tag on ProA-Biosensor can bind IL-13Ra2, His, Rat, His Tag with an affinity constant of 3.61 nM as determined in BLI assay (Gator® Prime).

IL-13Ra2, His, Rat

Immobilized IL-13Ra2, His, Rat, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-13, hFc Tag with the EC50 of 17.3ng/ml determined by ELISA.

IL-13Ra2, His, Rat

The purity of IL-13Ra2, His, Rat is greater than 95% as determined by SEC-HPLC.

IL-13Ra2, His, Rat

IL-13Ra2, His, Rat on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-13Ra2, His, Rat

Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
Z06422
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Product Introduction
Species Rat
Protein Construction
IL-13Ra2 (Leu24-Lys336)_x000D_
Accession # Q8VHK6
His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 37.51 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-13Ra2, His, Rat
  • IL-13Ra2, His, Rat

    Loaded Human IL-13, hFc Tag on ProA-Biosensor can bind IL-13Ra2, His, Rat, His Tag with an affinity constant of 3.61 nM as determined in BLI assay (Gator® Prime).

  • IL-13Ra2, His, Rat
  • IL-13Ra2, His, Rat

    Immobilized IL-13Ra2, His, Rat, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-13, hFc Tag with the EC50 of 17.3ng/ml determined by ELISA.

  • IL-13Ra2, His, Rat
  • IL-13Ra2, His, Rat

    The purity of IL-13Ra2, His, Rat is greater than 95% as determined by SEC-HPLC.

  • IL-13Ra2, His, Rat
  • IL-13Ra2, His, Rat

    IL-13Ra2, His, Rat on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
Synonyms CD213a2; IL-13 R alpha 2; IL13BP; IL13R; IL13RA2; IL-13R subunit alpha-2; IL-13Ra2

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.