
The purity of TMEM106B hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

TMEM106B hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
TMEM106B hFc Chimera, Mouse
TMEM106B is a well-recognised risk factor for FTD caused by GRN mutation. Elegant experiments have suggested that increased risk for FTD is due to elevated levels of TMEM106B (Nicholson et al, 2013; Gallagher et al, 2017). Therefore, recent work has explored the therapeutic potential of reducing TMEM106B levels, with initial results looking encouraging, as crossing a Grn-deficient mouse to a Tmem106b knockout showed a rescue in FTD-related behavioural defects and specific aspects of lysosome dysfunction (Klein et al, 2017).
Z06379 | |
|
|
¥63,425.00 | |
|
|
|
|
Ask us a question |