PTK7/CCK4, His, Mouse
PTK7/CCK4, His, Mouse

The purity ofPTK7/CCK4, His, Mouse is greater than 95% as determined by SEC-HPLC.

PTK7/CCK4, His, Mouse

PTK7/CCK4, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

PTK7/CCK4, His, Mouse

Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling.
Z06330
¥72,752.00

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Product Introduction
Species Mouse
Protein Construction
PTK7/CCK4 (Ala23-Thr696)_x000D_
Accession # Q8BKG3		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1 EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 75.67 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • PTK7/CCK4, His, Mouse
    • PTK7/CCK4, His, Mouse

    The purity ofPTK7/CCK4, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • PTK7/CCK4, His, Mouse
    • PTK7/CCK4, His, Mouse

    PTK7/CCK4, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Protein Tyrosine Kinase 7 (PTK7) is as a critical regulator of canonical and non-canonical Wnt-signaling during embryonic development and cancer cell formation. Disrupting PTK7 activity perturbs vertebrate nervous system development, and also promotes human cancer formation. Observations in different model systems suggest a complex cross-talk between PTK7 protein and Wnt signaling.
Synonyms CCK-4; PTK7

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.