OX40 Ligand/TNFSF4 hFc Chimera, Mouse

OX40 Ligand/TNFSF4 hFc Chimera, Mouse

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
Z06295
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Product Introduction
Species Mouse
Protein Construction
hFc OX40 Ligand/TNFSF4 (Ser51-Leu198)_x000D_
Accession # P43488
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per ug by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized OX40 Ligand/TNFSF4 hFc Chimera, Mouse at 5μg/ml (100μl/well) on the plate can bind Mouse OX40, His Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 42.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 52-56 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Background
Target Background Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L),which belongs to the tumor necrosis factor family. It is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.
Synonyms OX40L; OX-40L; OX4OL; CD252; TNFSF4; OX40 Ligand; CD134 ligand; CD134L; TXGP1; Glycoprotein Gp34

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.