OSMR beta, His, Mouse
OSMR Beta, His, Mouse

The purity of OSMR beta, His, Mouse is greater than 95% as determined by SEC-HPLC.

OSMR Beta, His, Mouse

OSMR beta, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

OSMR beta, His, Mouse

OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Z06293
¥55,963.00

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Product Introduction
Species Mouse
Protein Construction
OSMR beta (Glu24-Met737)_x000D_
Accession # O70458-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 83.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 115-140 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • OSMR Beta, His, Mouse
    • OSMR Beta, His, Mouse

    The purity of OSMR beta, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • OSMR Beta, His, Mouse
    • OSMR Beta, His, Mouse

    OSMR beta, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.
Synonyms IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ;IL-31R subunit β; IL-31R-β; OSMR β

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.