OSCAR hFc Chimera, Mouse
OSCAR HFc Chimera, Mouse

The purity of OSCAR hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

OSCAR HFc Chimera, Mouse

OSCAR hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

OSCAR hFc Chimera, Mouse

Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not differ between the cartilage pannus junction (CPJ) and non-CPJ regions in active RA.
Z06292
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Product Introduction
Species Mouse
Protein Construction
OSCAR (Asp19-Asn228)_x000D_
Accession # Q8VBT3-1		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 49.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • OSCAR HFc Chimera, Mouse
    • OSCAR HFc Chimera, Mouse

    The purity of OSCAR hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

  • OSCAR HFc Chimera, Mouse
    • OSCAR HFc Chimera, Mouse

    OSCAR hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and normal patients. OSCAR and tartrate-resistant acid phosphatase (TRAP) expression levels did not differ between the cartilage pannus junction (CPJ) and non-CPJ regions in active RA.
Synonyms mOSCAR; OSCAR; PIGR3; PIgR-3; Poly-Ig receptor 3; MGC33613

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.