Oncostatin M/OSM, His, Mouse
Oncostatin M/OSM, His, Mouse

The purity of Oncostatin M/OSM, His, Mouse is greater than 95% as determined by SEC-HPLC.

Oncostatin M/OSM, His, Mouse

Oncostatin M/OSM, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Oncostatin M/OSM, His, Mouse

OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Z06291
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Product Introduction
Species Mouse
Protein Construction
Oncostatin M/OSM (Asn25-Arg206)_x000D_
Accession # P53347		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 21.64 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • Oncostatin M/OSM, His, Mouse
    • Oncostatin M/OSM, His, Mouse

    The purity of Oncostatin M/OSM, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • Oncostatin M/OSM, His, Mouse
    • Oncostatin M/OSM, His, Mouse

    Oncostatin M/OSM, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Synonyms Oncostatin M; OSM; MGC20461; Oncostatin-M

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.