NOGOR, His, Mouse
NOGOR, His, Mouse

The purity of NOGOR, His, Mouse is greater than 95% as determined by SEC-HPLC.

NOGOR, His, Mouse

NOGOR, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

NOGOR, His, Mouse

NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
Z06286
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Product Introduction
Species Mouse
Protein Construction
NOGOR (Cys27-Ser447)_x000D_
Accession # Q99PI8		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 46.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • NOGOR, His, Mouse
    • NOGOR, His, Mouse

    The purity of NOGOR, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • NOGOR, His, Mouse
    • NOGOR, His, Mouse

    NOGOR, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
Synonyms Nogo receptor; RTN4R; NOGOR; NgR1; Nogo-66 receptor; NGR

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.