LTBR hFc Chimera, Mouse
LTBR HFc Chimera, Mouse

The purity of LTBR hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

LTBR HFc Chimera, Mouse

LTBR hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

LTBR hFc Chimera, Mouse

Components of lymphotoxin beta receptor (LTBR)-associated signaling complexes, including TRAF2, TRAF3, NIK, IKK1, and IKK2 have been shown to participate in the coupling of LTBR to NFkappaB. TRAF3 functions as a negative regulator of LTBR signaling via both canonical and non-canonical NFkappaB pathways by two distinct mechanisms. These effects of TRAF3 depletion did not require LTBR signaling and were consistent with autonomous activation of the non-canonical NFkappaB pathway.
Z06252
¥35,443.00

Ask us a question
Product Introduction
Species Mouse
Protein Construction
LTBR (Gln31-Leu223)_x000D_
Accession # P50284		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
> 95% as determined by HPLC
Endotoxin Level Less than 1 EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 48.5 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • LTBR HFc Chimera, Mouse
    • LTBR HFc Chimera, Mouse

    The purity of LTBR hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

  • LTBR HFc Chimera, Mouse
    • LTBR HFc Chimera, Mouse

    LTBR hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Components of lymphotoxin beta receptor (LTBR)-associated signaling complexes, including TRAF2, TRAF3, NIK, IKK1, and IKK2 have been shown to participate in the coupling of LTBR to NFkappaB. TRAF3 functions as a negative regulator of LTBR signaling via both canonical and non-canonical NFkappaB pathways by two distinct mechanisms. These effects of TRAF3 depletion did not require LTBR signaling and were consistent with autonomous activation of the non-canonical NFkappaB pathway.
Synonyms TNFCR; TNFR3; TNFRSF3; LTBR; CD18; TNFR2-RP; TNFR-RP; LT-BETA-R; TNF-R-III; D12S370; LT-β-R

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.