L1CAM, His, Mouse
L1CAM, His, Mouse

The purity of L1CAM, His, Mouse is greater than 95% as determined by SEC-HPLC.

L1CAM, His, Mouse

L1CAM, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

L1CAM, His, Mouse

L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
Z06235
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Product Introduction
Species Mouse
Protein Construction
L1CAM (Ile20-Glu1123)_x000D_
Accession # P11627		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per ug by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 125.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 160-180 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • L1CAM, His, Mouse
    • L1CAM, His, Mouse

    The purity of L1CAM, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • L1CAM, His, Mouse
    • L1CAM, His, Mouse

    L1CAM, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
Synonyms N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5; CALL; CHL1; CHL-1; FLJ44930; L1CAM-2; MGC132578; HSAS; HSAS1; MASA; S10; SPG1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.