IL-9, His, Mouse
IL-9, His, Mouse

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is < 3 ng/mL.

IL-9, His, Mouse

The purity of IL-9, His, Mouse is greater than 95% as determined by SEC-HPLC.

IL-9, His, Mouse

IL-9, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-9, His, Mouse

IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.
Z06217
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Product Introduction
Species Mouse
Protein Construction
IL-9 (Gln19-Pro144)
Accession # P15247		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 15.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-9, His, Mouse
    • IL-9, His, Mouse

    Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is < 3 ng/mL.

  • IL-9, His, Mouse
    • IL-9, His, Mouse

    The purity of IL-9, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • IL-9, His, Mouse
    • IL-9, His, Mouse

    IL-9, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma.
Synonyms Interleukin-9; IL-9; Cytokine P40; T-cell growth factor P40; HP40; P40

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.