IL-6 R alpha/CD126, His, Mouse
IL-6 R Alpha/CD126, His, Mouse

The purity of IL-6 R alpha/CD126, His, Mouse is greater than 95% as determined by SEC-HPLC.

IL-6 R Alpha/CD126, His, Mouse

IL-6 R alpha/CD126, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-6 R alpha/CD126, His, Mouse

The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.
Z06215
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Product Introduction
Species Mouse
Protein Construction
IL-6 R alpha/CD126 (Leu20-Pro364)_x000D_
Accession # P22272		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 39.21 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-6 R Alpha/CD126, His, Mouse
    • IL-6 R Alpha/CD126, His, Mouse

    The purity of IL-6 R alpha/CD126, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • IL-6 R Alpha/CD126, His, Mouse
    • IL-6 R Alpha/CD126, His, Mouse

    IL-6 R alpha/CD126, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expressed.
Synonyms IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; IL6R; CD126; IL6RQ; gp80

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.