IL-3 R alpha/CD123, His, Mouse
IL-3 R Alpha/CD123, His, Mouse

The purity of IL-3 R alpha/CD123, His, Mouse is greater than 95% as determined by SEC-HPLC.

IL-3 R Alpha/CD123, His, Mouse

IL-3 R alpha/CD123, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-3 R alpha/CD123, His, Mouse

Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
Z06210
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Product Introduction
Species Mouse
Protein Construction
IL-3 R alpha/CD123 (Ser17-Lys331)_x000D_
Accession # P26952-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Loaded Mouse IL­3, hFc Tag on ProA­Biosensor can bind Mouse IL­3 R alpha, His Tag in BLI assay (Gator® Prime). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 36.12 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-3 R Alpha/CD123, His, Mouse
    • IL-3 R Alpha/CD123, His, Mouse

    The purity of IL-3 R alpha/CD123, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • IL-3 R Alpha/CD123, His, Mouse
    • IL-3 R Alpha/CD123, His, Mouse

    IL-3 R alpha/CD123, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.
Synonyms CD123; IL-3R subunit alpha; IL3R; IL3RA; IL-3Ra; IL3RAY; IL3RX; IL3RY; IL-3 R alpha

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.