IL-2, His & Avi, Mouse
IL-2, His & Avi, Mouse

Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/mL. (QC Test)

IL-2, His & Avi, Mouse

The purity of IL-2, His & Avi, Mouse is greater than 95% as determined by SEC-HPLC.

IL-2, His & Avi, Mouse

IL-2, His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-2, His & Avi, Mouse

Mouse IL-2 R alpha, His Tag immobilized on CM5 Chip can bind IL-2, His & Avi, Mouse, His Tag with an affinity constant of 30.49 nM as determined in SPR assay (Biacore T200).

IL-2, His & Avi, Mouse

Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells.
Z06199
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Product Introduction
Species Mouse
Protein Construction
Avi His IL-2 (Ala21-Gln169)_x000D_
Accession # P04351-1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per ug by the LAL method.
Biological Activity Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 20.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 27-30 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-2, His & Avi, Mouse
    • IL-2, His & Avi, Mouse

    Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 0.5-2 ng/mL. (QC Test)

  • IL-2, His & Avi, Mouse
    • IL-2, His & Avi, Mouse

    The purity of IL-2, His & Avi, Mouse is greater than 95% as determined by SEC-HPLC.

  • IL-2, His & Avi, Mouse
    • IL-2, His & Avi, Mouse

    IL-2, His & Avi, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • IL-2, His & Avi, Mouse
    • IL-2, His & Avi, Mouse

    Mouse IL-2 R alpha, His Tag immobilized on CM5 Chip can bind IL-2, His & Avi, Mouse, His Tag with an affinity constant of 30.49 nM as determined in SPR assay (Biacore T200).


Background
Target Background Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells.
Synonyms IL2; T-cell growth factor; TCGF; Aldesleukin

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.