GITR Ligand/TNFSF18 hFc Chimera, Mouse
GITR Ligand/TNFSF18 HFc Chimera, Mouse

GITR Ligand/TNFSF18 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GITR Ligand/TNFSF18 hFc Chimera, Mouse

Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.
Z06144
¥67,155.00

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Product Introduction
Species Mouse
Protein Construction
hFc GITR Ligand/TNFSF18 (Thr47-Ser173)_x000D_
Accession # Q7TS55
N-term C-term
Purity > 95% as determined by Bis-­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 41.8 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GITR Ligand/TNFSF18 HFc Chimera, Mouse
    • GITR Ligand/TNFSF18 HFc Chimera, Mouse

    GITR Ligand/TNFSF18 hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.
Synonyms TNFSF18; AITRL; TL6; GITRL; GITR Ligand

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.