GAS6, His, Mouse
GAS6, His, Mouse

Immobilized GAS6, His, Mouse, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human Axl, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA.

GAS6, His, Mouse

The purity of GAS6, His, Mouse is greater than 95% as determined by SEC-HPLC.

GAS6, His, Mouse

GAS6, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GAS6, His, Mouse

Mouse AXL, His Tag immobilized on CM5 Chip can bind GAS6, His, Mouse, His Tag with an affinity constant of 15.62 nM as determined in SPR assay (Biacore T200).

GAS6, His, Mouse

Mouse TYRO3, His Tag immobilized on CM5 Chip can bind GAS6, His, Mouse, His Tag with an affinity constant of 11.31 μM as determined in SPR assay (Biacore T200).

GAS6, His, Mouse

Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
Z06135
¥72,752.00

Ask us a question
Product Introduction
Species Mouse
Protein Construction
GAS6 (Val28-Pro674)
Accession # Q61592		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 73.09 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 74-90 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GAS6, His, Mouse
    • GAS6, His, Mouse

    Immobilized GAS6, His, Mouse, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human Axl, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA.

  • GAS6, His, Mouse
    • GAS6, His, Mouse

    The purity of GAS6, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • GAS6, His, Mouse
    • GAS6, His, Mouse

    GAS6, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • GAS6, His, Mouse
    • GAS6, His, Mouse

    Mouse AXL, His Tag immobilized on CM5 Chip can bind GAS6, His, Mouse, His Tag with an affinity constant of 15.62 nM as determined in SPR assay (Biacore T200).

  • GAS6, His, Mouse
    • GAS6, His, Mouse

    Mouse TYRO3, His Tag immobilized on CM5 Chip can bind GAS6, His, Mouse, His Tag with an affinity constant of 11.31 μM as determined in SPR assay (Biacore T200).


Background
Target Background Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
Synonyms GAS-6; AXLLG; GAS6; DKFZp666G247; FLJ34709

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.