
The purity of Fc Epsilon RI alpha/FCER1a hFc Chimera, Mouse is greater than 95% as determined by SEC-HPLC.

Fc Epsilon RI alpha/FCER1a hFc Chimera, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Fc Epsilon RI alpha/FCER1a hFc Chimera, Mouse
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.
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