DSG-2/Desmoglein-2, His, Mouse
DSG-2/Desmoglein-2, His, Mouse

DSG-2/Desmoglein-2, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

DSG-2/Desmoglein-2, His, Mouse

Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
Z06090
¥63,425.00

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Product Introduction
Species Mouse
Protein Construction
DSG-2/Desmoglein-2 (Ala55-Ala618)_x000D_
Accession # O55111		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 63.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • DSG-2/Desmoglein-2, His, Mouse
    • DSG-2/Desmoglein-2, His, Mouse

    DSG-2/Desmoglein-2, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
Synonyms Desmoglein-2; HDGC; DSG2; CDHF5; ARVC10; CMD1BB; MGC117036; MGC117037

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.