BCAM, His, Mouse
BCAM, His, Mouse

The purity of BCAM, His, Mouse is greater than 95% as determined by SEC-HPLC.

BCAM, His, Mouse

BCAM, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

BCAM, His, Mouse

Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
Z06030
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Product Introduction
Species Mouse
Protein Construction
BCAM (Glu26-Ala541)_x000D_
Accession # Q9R069		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 57.95 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • BCAM, His, Mouse
    • BCAM, His, Mouse

    The purity of BCAM, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • BCAM, His, Mouse
    • BCAM, His, Mouse

    BCAM, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.
Synonyms LU; MSK19; Gplu; CD239; Lutheran;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.