B7-H4, His, Mouse
B7-H4, His, Mouse

The purity of B7-H4, His, Mouse is greater than 95% as determined by SEC-HPLC.

B7-H4, His, Mouse

B7-H4, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

B7-H4, His, Mouse

B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status .
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Product Introduction
Species Mouse
Protein Construction
B7-H4 (Leu25-Gly257)_x000D_
Accession # Q7TSP5		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 26.70 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 48-68 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • B7-H4, His, Mouse
    • B7-H4, His, Mouse

    The purity of B7-H4, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • B7-H4, His, Mouse
    • B7-H4, His, Mouse

    B7-H4, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status .
Synonyms B7H4; B7-H4; B7S1; B7h.5; B7x; FLJ22418; VTCN1; PRO1291

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.