B7-1/CD80, His, Mouse
B7-1/CD80, His, Mouse

The purity of B7-1/CD80, His, Mouse is greater than 95% as determined by SEC-HPLC.

B7-1/CD80, His, Mouse

B7-1/CD80, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

B7-1/CD80, His, Mouse

Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
Z06020
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Product Introduction
Species Mouse
Protein Construction
B7-1/CD80 (Val38-Asn246)_x000D_
Accession # Q00609-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 24.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • B7-1/CD80, His, Mouse
    • B7-1/CD80, His, Mouse

    The purity of B7-1/CD80, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • B7-1/CD80, His, Mouse
    • B7-1/CD80, His, Mouse

    B7-1/CD80, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
Synonyms CD80 molecule; B7; B71; B7-1; BB1; CD28LG1; CD80; B7.1; CD28LG1; LAB7

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.