APOE/Apolipo E, His, Mouse
APOE/Apolipo E, His, Mouse

APOE/Apolipo E, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

APOE/Apolipo E, His, Mouse

Mouse LILRB4, His Tag immobilized on CM5 Chip can bind APOE/Apolipo E, His, Mouse, His Tag with an affinity constant of 5.08 nM as determined in SPR assay (Biacore T200).

APOE/Apolipo E, His, Mouse

Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
Z06010
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Product Introduction
Species Mouse
Protein Construction
APOE/Apolipoprotein E (Glu19-Gln311)_x000D_
Accession # P08226		 His
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 35.1 kDa
Apparent Molecular Weight The protein has a predicted MW of 35.1 kDa same as Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Examples
  • APOE/Apolipo E, His, Mouse
    • APOE/Apolipo E, His, Mouse

    APOE/Apolipo E, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • APOE/Apolipo E, His, Mouse
    • APOE/Apolipo E, His, Mouse

    Mouse LILRB4, His Tag immobilized on CM5 Chip can bind APOE/Apolipo E, His, Mouse, His Tag with an affinity constant of 5.08 nM as determined in SPR assay (Biacore T200).


Background
Target Background Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).
Synonyms Apolipoprotein E; Apo-E; APOE; apolipo E

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.